This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
protein
product name :
Human MEL18 (aa 244-286) Control Fragment Recombinant Protein
catalog :
RP-107245
quantity :
100 uL
price :
US 259.00
product information
Product Type :
Protein
Product Name :
Human MEL18 (aa 244-286) Control Fragment Recombinant Protein
Catalog # :
RP-107245
Quantity :
100 uL
Price :
US 259.00
Clonality :
Recombinant
Purity :
purified
Reactivity :
Human
Applications :
Blocking Assay: Assay-dependent, Control: Assay-dependent
Species :
Human
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses.
Format :
Liquid
Applications w/Dilutions :
Blocking Assay: Assay-dependent, Control: Assay-dependent
Aliases :
DNA-binding protein Mel-18; Mel18; Mel-18; Melanoma nuclear protein 18; MGC10545; Pcgf2; polycomb group ring finger 2; polycomb group RING finger protein 2; RING finger protein 110; RNF110; Zfp144; Zfp-144; Zinc finger protein 144; zinc finger protein 144 (Mel-18) (human homolog); ZNF144
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA