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protein

Human ZCCHC9 (aa 178-250) Control Fragment Recombinant Protein

RP-106780

100 uL

US 259.00

Human ZCCHC9 (aa 178-250) Control Fragment Recombinant Protein

RP-106780

100 uL

US 259.00

Recombinant

purified

Human

Blocking Assay: Assay-dependent, Control: Assay-dependent

Human

-20 C, Avoid Freeze/Thaw Cycles

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZCCHC9 (zinc finger, CCHC domain containing 9) is a 271 amino acid protein that contains four CCHC-type zinc finger, suggesting a role in transcriptional regulation. The gene encoding ZCCHC9 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

Liquid

Blocking Assay: Assay-dependent, Control: Assay-dependent

PPP1R41; protein phosphatase 1, regulatory subunit 41; ZCCHC9; Zinc finger CCHC domain-containing protein 9; zinc finger CCHC-type containing 9; zinc finger, CCHC domain containing 9