Human NO66 (aa 141-272) Control Fragment Recombinant Protein | Invitrogen RP-105694 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Human NO66 (aa 141-272) Control Fragment Recombinant Protein

catalog :

RP-105694

quantity :

100 uL

price :

US 259.00

product information

Product Type :

Protein

Product Name :

Human NO66 (aa 141-272) Control Fragment Recombinant Protein

Catalog # :

RP-105694

Quantity :

100 uL

Price :

US 259.00

Clonality :

Recombinant

Purity :

purified

Reactivity :

Human

Applications :

Blocking Assay: Assay-dependent, Control: Assay-dependent

Species :

Human

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 'Lys-4' (H3K4me1) residues, while it has weaker activity for dimethylated H3 'Lys-36' (H3K36me2). Also catalyzes the hydroxylation of 60S ribosomal protein L8 on 'His-216'. Acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation. May also play a role in ribosome biogenesis and in the replication or remodeling of certain heterochromatic region. Participates in MYC-induced transcriptional activation. [UniProt]

Format :

Liquid

Applications w/Dilutions :

Blocking Assay: Assay-dependent, Control: Assay-dependent

Aliases :

2410016O06Rik; 60S ribosomal protein L8 histidine hydroxylase; bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66; C14orf169; chromosome 14 open reading frame 169; FLJ21802; histone lysine demethylase NO66; hsNO66; lysine-specific demethylase NO66; Mapjd; MNCb-7109; myc associated protein with JmjC domain; MYC-associated protein with JmjC domain; NO66; nucleolar protein 66; RGD1307704; Ribosomal oxygenase 1; Ribosomal oxygenase NO66; RIKEN cDNA 2410016O06 gene; Riox1; ROX; similar to RIKEN cDNA 2410016O06; up-regulated in lung cancer 2; URLC2