Human TMEM52B (aa 127-183) Control Fragment Recombinant Protein | Invitrogen RP-104253 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Human TMEM52B (aa 127-183) Control Fragment Recombinant Protein

catalog :

RP-104253

quantity :

100 uL

price :

US 259.00

product information

Product Type :

Protein

Product Name :

Human TMEM52B (aa 127-183) Control Fragment Recombinant Protein

Catalog # :

RP-104253

Quantity :

100 uL

Price :

US 259.00

Clonality :

Recombinant

Purity :

purified

Reactivity :

Human

Applications :

Blocking Assay: Assay-dependent, Control: Assay-dependent

Species :

Human

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

The TMEM52B gene encodes a transmembrane protein that is widely expressed across various normal human tissues, suggesting its fundamental role in maintaining cellular integrity. TMEM52B is part of the transmembrane protein (TMEM) family, which contains proteins that span biological membranes, including the lipid bilayer of the plasma membrane and organelle membranes. This gene is notably involved in tumor biology, where it modulates cancer cell survival and invasion. Studies have shown that suppression of TMEM52B expression can enhance the aggressiveness of cancer cells, indicating its potential as a tumor suppressor gene. Specifically, TMEM52B isoforms such as P18 and P20 have been found to differentially influence tumor dynamics, particularly in the context of nasopharyngeal carcinoma (NPC). While its exact molecular mechanisms remain largely unknown, the regulation of TMEM52B is crucial for controlling tumor growth and metastasis. Therefore, understanding its role could provide insights into therapeutic strategies aimed at curbing cancer progression.

Format :

Liquid

Applications w/Dilutions :

Blocking Assay: Assay-dependent, Control: Assay-dependent

Aliases :

C12orf59; TMEM52B; Transmembrane protein 52B; UNQ5927/PRO19821