This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
protein
product name :
Human CHD5 (aa 1574-1659) Control Fragment Recombinant Protein
catalog :
RP-103713
quantity :
100 uL
price :
US 259.00
product information
Product Type :
Protein
Product Name :
Human CHD5 (aa 1574-1659) Control Fragment Recombinant Protein
Catalog # :
RP-103713
Quantity :
100 uL
Price :
US 259.00
Clonality :
Recombinant
Purity :
purified
Reactivity :
Human
Applications :
Blocking Assay: Assay-dependent, Control: Assay-dependent
Species :
Human
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
CHD5 (Chromodomain helicase DNA binding protein 5) is a member of the SNF2/RAD54 helicase family of chromatin remodeling and DNA-binding proteins (CDH proteins). Heavily expressed in both fetal and adult brain, CHD5 plays a role in nervous system development and acts as a tumor suppressor via the Arf/p53 pathway. CHD5, along with other chromo-domain proteins, forms remodeling complexes, such as NuRD, that promote normal neuroblast maturation and are thought to prevent overexpression of neuronal cells. Errors in these chromatin remodeling complexes can leave the cell in a perpetual state of growth, preventing differentiation and leading to tumor formation. Due to the importance of the CHD proteins in proper brain development, deletions in the gene encoding CHD5 are commonly found in neuroblastomas, suggesting that CHD5 deficiency may lead to malignant cell transformation and metastasis.
Format :
Liquid
Applications w/Dilutions :
Blocking Assay: Assay-dependent, Control: Assay-dependent
Aliases :
4930532L22Rik; ATP-dependent helicase CHD5; AW060752; B230399N07Rik; CHD5; CHD-5; chromodomain helicase DNA binding protein 5; chromodomain-helicase-DNA-binding protein 5; KIAA0444
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA