Human AKAP5 Control Fragment Recombinant Protein | Invitrogen RP-103170 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Human AKAP5 Control Fragment Recombinant Protein

catalog :

RP-103170

quantity :

100 uL

price :

US 259.00

product information

Product Type :

Protein

Product Name :

Human AKAP5 Control Fragment Recombinant Protein

Catalog # :

RP-103170

Quantity :

100 uL

Price :

US 259.00

Clonality :

Recombinant

Purity :

purified

Reactivity :

Human

Applications :

Blocking Assay: Assay-dependent, Control: Assay-dependent

Species :

Human

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

AKAPs (A-kinase anchoring proteins), as their name implies, are a family of scaffolding proteins that bind regulatory subunits of Protein Kinase A (PKA) thus localizing PKA activity to distinct regions of the cell. Beyond a common amphipathic alpha helix that is responsible for recruiting the PKA regulatory subunit (RI alpha, RII alpha, RI beta, or RII beta), individual AKAPs contain additional domains responsible for the recrutiment of additional signaling proteins (phosphodiesterases, phosphatases, cytoskeletal components, other kinase, etc.) or restricting AKAP to a specific subcellular location. AKAP5 (also known as P75, AKAP75, or AKAP79) is predominantly expressed in neuronal tissues and cells where it serves to localize type II PKA to post-synaptic densities. AKAP5 specifically binds to the regulatory subunit of PKAII beta, anchoring the enzyme to the plasma membrane and sites of cytoskeletal/membrane junctions. The other binding domains of AKAP5 have been shown to interact with calmodulin, PP2B, and calcineurin suggesting that AKAP5 may act to coordinate the cAMP- and Ca2+-sensing pathways in various cell types.

Format :

Liquid

Applications w/Dilutions :

Blocking Assay: Assay-dependent, Control: Assay-dependent

Aliases :

3526401B18Rik; A kinase (PRKA) anchor protein 5; AKAP 150; AKAP 5; AKAP 79; AKAP150; AKAP5; AKAP-5; AKAP75; AKAP79; A-kinase anchor protein 150 kDa; A-kinase anchor protein 5; A-kinase anchor protein 79 kDa; A-kinase anchoring protein 5; A-kinase anchoring protein 75/79; BB098886; cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein; Gm258; H21; P150; RII-B-binding protein