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protein

Human RAB5C (aa 156-216) Control Fragment Recombinant Protein

RP-102038

100 uL

US 259.00

Human RAB5C (aa 156-216) Control Fragment Recombinant Protein

RP-102038

100 uL

US 259.00

Recombinant

purified

Human

Blocking Assay: Assay-dependent, Control: Assay-dependent

Human

-20 C, Avoid Freeze/Thaw Cycles

The Ras-related superfamily of guanine nucleotide binding proteins, which includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies, exhibit 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the SEC4 protein, which is 40% homologous to Rab proteins, is associated with secretory vesicles.

Liquid

Blocking Assay: Assay-dependent, Control: Assay-dependent

AI326010; L1880; RAB; RAB5B; RAB5B, member RAS oncogene family; RAB5C; Rab5c protein; RAB5C, member of RAS oncogene family; RAB5C, member RAS oncogene family; RAB5C, member RAS oncogene family isoform b; RAB5CL; RAB5L; RABL; Ras-related protein Rab-5C; small GTPase; wu:fb98b08; wu:fi16g01