CD31 Monoclonal Antibody (390), FITC | Invitrogen RM5201 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD31 Monoclonal Antibody (390), FITC

catalog :

RM5201

quantity :

1 mL

price :

US 168.00

clonality :

monoclonal

host :

rat

conjugate :

FITC

clone name :

390

reactivity :

human, mouse, rat

application :

immunohistochemistry, flow cytometry, immunohistochemistry - frozen section, blocking or activating experiments

more info or order :

Invitrogen product webpage

citations: 16

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; 1:100; loading ...; fig 1b	Hemanthakumar K, Fang S, Anisimov A, Mäyränpää M, Mervaala E, Kivela R. Cardiovascular disease risk factors induce mesenchymal features and senescence in mouse cardiac endothelial cells. elife. 2021;10: pubmed publisher
flow cytometry; mouse; 1:100; loading ...; fig s6c	Diéguez Hurtado R, Kato K, Giaimo B, Nieminen Kelhä M, Arf H, Ferrante F, et al. Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes. Nat Commun. 2019;10:2817 pubmed publisher
flow cytometry; mouse; loading ...; fig 2d	Ganta V, Choi M, Kutateladze A, Annex B. VEGF165b Modulates Endothelial VEGFR1-STAT3 Signaling Pathway and Angiogenesis in Human and Experimental Peripheral Arterial Disease. Circ Res. 2017;120:282-295 pubmed publisher
flow cytometry; mouse; 1:25; loading ...	Lukjanenko L, Jung M, Hegde N, Perruisseau Carrier C, Migliavacca E, Rozo M, et al. Loss of fibronectin from the aged stem cell niche affects the regenerative capacity of skeletal muscle in mice. Nat Med. 2016;22:897-905 pubmed publisher
immunohistochemistry; mouse; fig 2	Ishida R, Kami D, Kusaba T, Kirita Y, Kishida T, Mazda O, et al. Kidney-specific Sonoporation-mediated Gene Transfer. Mol Ther. 2016;24:125-34 pubmed publisher
immunohistochemistry; mouse	Yeung H, Lo P, Ng D, Fong W. Anti-tumor immunity of BAM-SiPc-mediated vascular photodynamic therapy in a BALB/c mouse model. Cell Mol Immunol. 2017;14:223-234 pubmed publisher
flow cytometry; human; fig 1	Alessio A, Beltrame M, Nascimento M, Vicente C, de Godoy J, Silva J, et al. Circulating progenitor and mature endothelial cells in deep vein thrombosis. Int J Med Sci. 2013;10:1746-54 pubmed publisher
blocking or activating experiments; rat; 1:40; fig 1 immunohistochemistry - frozen section; rat	DeLisser H, Christofidou Solomidou M, Strieter R, Burdick M, Robinson C, Wexler R, et al. Involvement of endothelial PECAM-1/CD31 in angiogenesis. Am J Pathol. 1997;151:671-7 pubmed
	Duan Q, Zhang Q, Nie K, Huang R, Yang J, He P, et al. Myo1d promotes alpha-synuclein transfer from brain microvascular endothelial cells to pericytes through tunneling nanotubes. iScience. 2023;26:107458 pubmed publisher
	Huang Y, Cui D, Chen L, Tong H, Wu H, Muller G, et al. A pref-1-controlled non-inflammatory mechanism of insulin resistance. iScience. 2023;26:106923 pubmed publisher
	Daneva Z, Chen Y, Ta H, Manchikalapudi V, Bazaz A, Laubach V, et al. Endothelial IK and SK channel activation decreases pulmonary arterial pressure and vascular remodeling in pulmonary hypertension. Pulm Circ. 2023;13:e12186 pubmed publisher
	Redder E, Kirschnick N, Bobe S, Hägerling R, Hansmeier N, Kiefer F. Vegfr3-tdTomato, a reporter mouse for microscopic visualization of lymphatic vessel by multiple modalities. PLoS ONE. 2021;16:e0249256 pubmed publisher
	Dammone G, Karaz S, Lukjanenko L, Winkler C, Sizzano F, Jacot G, et al. PPARγ Controls Ectopic Adipogenesis and Cross-Talks with Myogenesis During Skeletal Muscle Regeneration. Int J Mol Sci. 2018;19: pubmed publisher
	Kato K, Diéguez Hurtado R, Park D, Hong S, Kato Azuma S, Adams S, et al. Pulmonary pericytes regulate lung morphogenesis. Nat Commun. 2018;9:2448 pubmed publisher
	Cao J, Ehling M, März S, Seebach J, Tarbashevich K, Sixta T, et al. Polarized actin and VE-cadherin dynamics regulate junctional remodelling and cell migration during sprouting angiogenesis. Nat Commun. 2017;8:2210 pubmed publisher
	Xue S, Yang H, Qiao J, Pu F, Jiang J, Hubbard K, et al. Protein MRI contrast agent with unprecedented metal selectivity and sensitivity for liver cancer imaging. Proc Natl Acad Sci U S A. 2015;112:6607-12 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD31 Monoclonal Antibody (390), FITC

Catalog # :

RM5201

Quantity :

1 mL

Price :

US 168.00

Clonality :

Monoclonal

Purity :

purified

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: Assay-dependent

Species :

Mouse

Clone :

390

Isotype :

IgG2a, kappa

Storage :

4 C, store in dark

Description :

CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.

Immunogen :

Mouse 32D leukocyte cell line.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-dependent

Aliases :

C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule

more info or order :

Invitrogen product webpage