Reference |
---|
Johnson S, Ranxhi B, Libohova K, Tsou W, Todi S. Ubiquitin-interacting motifs of ataxin-3 regulate its polyglutamine toxicity through Hsc70-4-dependent aggregation. elife. 2020;9: pubmed publisher
|
Walsh M, Janzen E, Wingrove E, Hosseinibarkooie S, Muela N, Davidow L, et al. Genetic modifiers ameliorate endocytic and neuromuscular defects in a model of spinal muscular atrophy. BMC Biol. 2020;18:127 pubmed publisher
|
Kottmeier R, Bittern J, Schoofs A, Scheiwe F, Matzat T, Pankratz M, et al. Wrapping glia regulates neuronal signaling speed and precision in the peripheral nervous system of Drosophila. Nat Commun. 2020;11:4491 pubmed publisher
|
Buljan M, Ciuffa R, van Drogen A, Vichalkovski A, Mehnert M, Rosenberger G, et al. Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases. Mol Cell. 2020;79:504-520.e9 pubmed publisher
|
Magnussen S, Toraskar J, Wilhelm I, Haskó J, Figenschau S, Molnar J, et al. Nephronectin promotes breast cancer brain metastatic colonization via its integrin-binding domains. Sci Rep. 2020;10:12237 pubmed publisher
|
Bader I, McTiernan N, Darbakk C, Boltshauser E, Ree R, Ebner S, et al. Severe syndromic ID and skewed X-inactivation in a girl with NAA10 dysfunction and a novel heterozygous de novo NAA10 p.(His16Pro) variant - a case report. BMC Med Genet. 2020;21:153 pubmed publisher
|
Goodnight D, Rine J. S-phase-independent silencing establishment in Saccharomyces cerevisiae. elife. 2020;9: pubmed publisher
|
de Jonge W, Brok M, Kemmeren P, Holstege F. An Optimized Chromatin Immunoprecipitation Protocol for Quantification of Protein-DNA Interactions. STAR Protoc. 2020;1:100020 pubmed publisher
|
Brett J, Arjona M, Ikeda M, Quarta M, de Morrée A, Egner I, et al. Exercise rejuvenates quiescent skeletal muscle stem cells in old mice through restoration of Cyclin D1. Nat Metab. 2020;2:307-317 pubmed publisher
|
Santos J, Boucher D, Schneider L, Demarco B, Dilucca M, Shkarina K, et al. Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria. Nat Commun. 2020;11:3276 pubmed publisher
|
Rao C, Malaguti M, Mason J, Lowell S. The transcription factor E2A drives neural differentiation in pluripotent cells. Development. 2020;147: pubmed publisher
|
Adriaenssens E, Tedesco B, Mediani L, Asselbergh B, Crippa V, Antoniani F, et al. BAG3 Pro209 mutants associated with myopathy and neuropathy relocate chaperones of the CASA-complex to aggresomes. Sci Rep. 2020;10:8755 pubmed publisher
|
Kadota S, Ou J, Shi Y, Lee J, Sun J, Yildirim E. Nucleoporin 153 links nuclear pore complex to chromatin architecture by mediating CTCF and cohesin binding. Nat Commun. 2020;11:2606 pubmed publisher
|
Bernatik O, Paclíková P, Sri Ganji R, Bryja V. Activity of Smurf2 Ubiquitin Ligase Is Regulated by the Wnt Pathway Protein Dishevelled. Cells. 2020;9: pubmed publisher
|
Hoffmann M, Kleine Weber H, Pohlmann S. A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells. Mol Cell. 2020;78:779-784.e5 pubmed publisher
|
Zhang X, Xu Y, Chen B, Kang L. Long noncoding RNA PAHAL modulates locust behavioural plasticity through the feedback regulation of dopamine biosynthesis. PLoS Genet. 2020;16:e1008771 pubmed publisher
|
Soliman S, Stark A, Gardner M, Harshman S, Breece C, Amari F, et al. Tagging enhances histochemical and biochemical detection of Ran Binding Protein 9 in vivo and reveals its interaction with Nucleolin. Sci Rep. 2020;10:7138 pubmed publisher
|
Leech C, Flynn M, Arsenault H, Ou J, Liu H, Zhu L, et al. The coordinate actions of calcineurin and Hog1 mediate the stress response through multiple nodes of the cell cycle network. PLoS Genet. 2020;16:e1008600 pubmed publisher
|
Cammarata Mouchtouris A, Nguyen X, Acker A, Bonnay F, Goto A, Orian A, et al. Hyd ubiquitinates the NF-κB co-factor Akirin to operate an effective immune response in Drosophila. PLoS Pathog. 2020;16:e1008458 pubmed publisher
|
Glanz A, Chawla K, Fabry S, Subramanian G, Garcia J, Jay B, et al. High Throughput Screening of FDA-Approved Drug Library Reveals the Compounds that Promote IRF3-Mediated Pro-Apoptotic Pathway Inhibit Virus Replication. Viruses. 2020;12: pubmed publisher
|
Rebowski G, Boczkowska M, Drazic A, Ree R, Goris M, Arnesen T, et al. Mechanism of actin N-terminal acetylation. Sci Adv. 2020;6:eaay8793 pubmed publisher
|
Mueller W, Jakob P, Sun H, Clauder Münster S, Ghidelli Disse S, Ordonez D, et al. Loss of N-Glycanase 1 Alters Transcriptional and Translational Regulation in K562 Cell Lines. G3 (Bethesda). 2020;10:1585-1597 pubmed publisher
|
Choi M, Graves M, Matoo S, Storad Z, El Sheikh Idris R, Weck M, et al. The small EF-hand protein CALML4 functions as a critical myosin light chain within the intermicrovillar adhesion complex. J Biol Chem. 2020;295:9281-9296 pubmed publisher
|
Cao X, Lilla S, Cao Z, Pringle M, Oka O, Robinson P, et al. The mammalian cytosolic thioredoxin reductase pathway acts via a membrane protein to reduce ER-localised proteins. J Cell Sci. 2020;133: pubmed publisher
|
Coste de Bagneaux P, von Elsner L, Bierhals T, Campiglio M, Johannsen J, Obermair G, et al. A homozygous missense variant in CACNB4 encoding the auxiliary calcium channel beta4 subunit causes a severe neurodevelopmental disorder and impairs channel and non-channel functions. PLoS Genet. 2020;16:e1008625 pubmed publisher
|
Yorozu A, Yamamoto E, Niinuma T, Tsuyada A, Maruyama R, Kitajima H, et al. Upregulation of adipocyte enhancer-binding protein 1 in endothelial cells promotes tumor angiogenesis in colorectal cancer. Cancer Sci. 2020;111:1631-1644 pubmed publisher
|
Xue Y, Theisen T, Rastogi S, Ferrel A, Quake S, Boothroyd J. A single-parasite transcriptional atlas of Toxoplasma Gondii reveals novel control of antigen expression. elife. 2020;9: pubmed publisher
|
Luo C, Balsa E, Perry E, Liang J, Tavares C, Vazquez F, et al. H3K27me3-mediated PGC1α gene silencing promotes melanoma invasion through WNT5A and YAP. J Clin Invest. 2020;130:853-862 pubmed publisher
|
Miyake N, Takahashi H, Nakamura K, Isidor B, Hiraki Y, Koshimizu E, et al. Gain-of-Function MN1 Truncation Variants Cause a Recognizable Syndrome with Craniofacial and Brain Abnormalities. Am J Hum Genet. 2020;106:13-25 pubmed publisher
|
Li Z, Huan C, Wang H, Liu Y, Liu X, Su X, et al. TRIM21-mediated proteasomal degradation of SAMHD1 regulates its antiviral activity. EMBO Rep. 2020;21:e47528 pubmed publisher
|
Lee B, Sanstrum B, Liu Y, Kwon S. Distinct role of Sirtuin 1 (SIRT1) and Sirtuin 2 (SIRT2) in inhibiting cargo-loading and release of extracellular vesicles. Sci Rep. 2019;9:20049 pubmed publisher
|
Dzimianski J, Scholte F, Williams I, Langley C, Freitas B, Spengler J, et al. Determining the molecular drivers of species-specific interferon-stimulated gene product 15 interactions with nairovirus ovarian tumor domain proteases. PLoS ONE. 2019;14:e0226415 pubmed publisher
|
Lapart J, Gottardo M, Cortier E, Duteyrat J, Augière C, Mangé A, et al. Dzip1 and Fam92 form a ciliary transition zone complex with cell type specific roles in Drosophila. elife. 2019;8: pubmed publisher
|
Derrer C, Mancini R, Vallotton P, Huet S, Weis K, Dultz E. The RNA export factor Mex67 functions as a mobile nucleoporin. J Cell Biol. 2019;218:3967-3976 pubmed publisher
|
Pathria G, Lee J, Hasnis E, Tandoc K, Scott D, Verma S, et al. Translational reprogramming marks adaptation to asparagine restriction in cancer. Nat Cell Biol. 2019;21:1590-1603 pubmed publisher
|
Alleva B, Clausen S, Koury E, Hefel A, Smolikove S. CRL4 regulates recombination and synaptonemal complex aggregation in the Caenorhabditis elegans germline. PLoS Genet. 2019;15:e1008486 pubmed publisher
|
Sharma P, Mahen R, Rossmann M, Stokes J, Hardwick B, Huggins D, et al. A cryptic hydrophobic pocket in the polo-box domain of the polo-like kinase PLK1 regulates substrate recognition and mitotic chromosome segregation. Sci Rep. 2019;9:15930 pubmed publisher
|
Lear T, McKelvey A, EVANKOVICH J, Rajbhandari S, Coon T, Dunn S, et al. KIAA0317 regulates pulmonary inflammation through SOCS2 degradation. JCI Insight. 2019;4: pubmed publisher
|
Mettelman R, O Brien A, Whittaker G, Baker S. Generating and evaluating type I interferon receptor-deficient and feline TMPRSS2-expressing cells for propagating serotype I feline infectious peritonitis virus. Virology. 2019;537:226-236 pubmed publisher
|
Wang H, He M, Willard B, Wu Q. Cross-linking, Immunoprecipitation and Proteomic Analysis to Identify Interacting Proteins in Cultured Cells. Bio Protoc. 2019;9: pubmed publisher
|
Hansen A, Hsieh T, Cattoglio C, Pustova I, Saldaña Meyer R, Reinberg D, et al. Distinct Classes of Chromatin Loops Revealed by Deletion of an RNA-Binding Region in CTCF. Mol Cell. 2019;76:395-411.e13 pubmed publisher
|
Fragoza R, Das J, Wierbowski S, Liang J, Tran T, Liang S, et al. Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations. Nat Commun. 2019;10:4141 pubmed publisher
|
Orozco S, Daniels B, Yatim N, Messmer M, Quarato G, Chen Harris H, et al. RIPK3 Activation Leads to Cytokine Synthesis that Continues after Loss of Cell Membrane Integrity. Cell Rep. 2019;28:2275-2287.e5 pubmed publisher
|
Li M, Fine R, Dinda M, Bekiranov S, Smith J. A Sir2-regulated locus control region in the recombination enhancer of Saccharomyces cerevisiae specifies chromosome III structure. PLoS Genet. 2019;15:e1008339 pubmed publisher
|
Sriramachandran A, Meyer Teschendorf K, Pabst S, Ulrich H, Gehring N, Hofmann K, et al. Arkadia/RNF111 is a SUMO-targeted ubiquitin ligase with preference for substrates marked with SUMO1-capped SUMO2/3 chain. Nat Commun. 2019;10:3678 pubmed publisher
|
Rai L, Singha R, Sanchez H, Chakraborty T, Chand B, Bachellier Bassi S, et al. The Candida albicans biofilm gene circuit modulated at the chromatin level by a recent molecular histone innovation. PLoS Biol. 2019;17:e3000422 pubmed publisher
|
Ortiz M, Ahmed S, Burns M, Henssen A, Hollmann T, Macarthur I, et al. Prohibitin is a prognostic marker and therapeutic target to block chemotherapy resistance in Wilms' tumor. JCI Insight. 2019;4: pubmed publisher
|
Boso G, Shaffer E, Liu Q, Cavanna K, Buckler White A, Kozak C. Evolution of the rodent Trim5 cluster is marked by divergent paralogous expansions and independent acquisitions of TrimCyp fusions. Sci Rep. 2019;9:11263 pubmed publisher
|
Penserga T, Kudumala S, Poulos R, GODENSCHWEGE T. A Role for Drosophila Amyloid Precursor Protein in Retrograde Trafficking of L1-Type Cell Adhesion Molecule Neuroglian. Front Cell Neurosci. 2019;13:322 pubmed publisher
|
Bryant E, Sunjevaric I, Berchowitz L, Rothstein R, Reid R. Rad5 dysregulation drives hyperactive recombination at replication forks resulting in cisplatin sensitivity and genome instability. Nucleic Acids Res. 2019;47:9144-9159 pubmed publisher
|
Ahn N, Kim W, Kim N, Park H, Lee S, Yoo J. The Interferon-Inducible Proteoglycan Testican-2/SPOCK2 Functions as a Protective Barrier against Virus Infection of Lung Epithelial Cells. J Virol. 2019;93: pubmed publisher
|
Scholte F, Hua B, Spengler J, Dzimianski J, Coleman McCray J, Welch S, et al. Stable Occupancy of the Crimean-Congo Hemorrhagic Fever Virus-Encoded Deubiquitinase Blocks Viral Infection. MBio. 2019;10: pubmed publisher
|
Abdusselamoglu M, Eroglu E, Burkard T, Knoblich J. The transcription factor odd-paired regulates temporal identity in transit-amplifying neural progenitors via an incoherent feed-forward loop. elife. 2019;8: pubmed publisher
|
Moskovskich A, Goldmann U, Kartnig F, Lindinger S, Konecka J, Fiume G, et al. The transporters SLC35A1 and SLC30A1 play opposite roles in cell survival upon VSV virus infection. Sci Rep. 2019;9:10471 pubmed publisher
|
Jesinkey S, Madiraju A, Alves T, Yarborough O, Cardone R, Zhao X, et al. Mitochondrial GTP Links Nutrient Sensing to β Cell Health, Mitochondrial Morphology, and Insulin Secretion Independent of OxPhos. Cell Rep. 2019;28:759-772.e10 pubmed publisher
|
George J, Jacobs H. Minimal effects of spargel (PGC-1) overexpression in a Drosophila mitochondrial disease model. Biol Open. 2019;8: pubmed publisher
|
Kim E, Roche K, Kulej K, Spruce L, Seeholzer S, Coen D, et al. SAMHD1 Modulates Early Steps during Human Cytomegalovirus Infection by Limiting NF-κB Activation. Cell Rep. 2019;28:434-448.e6 pubmed publisher
|
Georg I, Díaz Barreiro A, Morell M, Pey A, Alarcon Riquelme M. BANK1 interacts with TRAF6 and MyD88 in innate immune signaling in B cells. Cell Mol Immunol. 2019;: pubmed publisher
|
Rodrigues I, Pereira L, Lisboa J, Pereira C, Oliveira P, dos Santos N, et al. Involvement of Hsp90 and cyclophilins in intoxication by AIP56, a metalloprotease toxin from Photobacterium damselae subsp. piscicida. Sci Rep. 2019;9:9019 pubmed publisher
|
Guajardo R, Luginbuhl D, Han S, Luo L, Li J. Functional divergence of Plexin B structural motifs in distinct steps of Drosophila olfactory circuit assembly. elife. 2019;8: pubmed publisher
|
Cattoglio C, Pustova I, Walther N, Ho J, Hantsche Grininger M, Inouye C, et al. Determining cellular CTCF and cohesin abundances to constrain 3D genome models. elife. 2019;8: pubmed publisher
|
Sharma Y, Miladi M, Dukare S, Boulay K, Caudron Herger M, Groß M, et al. A pan-cancer analysis of synonymous mutations. Nat Commun. 2019;10:2569 pubmed publisher
|
Chiramel A, Meyerson N, McNally K, Broeckel R, Montoya V, Méndez Solís O, et al. TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation. Cell Rep. 2019;27:3269-3283.e6 pubmed publisher
|
Wang H, Wang L, Li S, Dong N, Wu Q. N-Glycan-calnexin interactions in human factor VII secretion and deficiency. Int J Biochem Cell Biol. 2019;113:67-74 pubmed publisher
|
Chen D, Liu X, Xia T, Tekcham D, Wang W, Chen H, et al. A Multidimensional Characterization of E3 Ubiquitin Ligase and Substrate Interaction Network. iScience. 2019;16:177-191 pubmed publisher
|
Thalmensi J, Pliquet E, Liard C, Chamel G, Kreuz C, Bestetti T, et al. A DNA telomerase vaccine for canine cancer immunotherapy. Oncotarget. 2019;10:3361-3372 pubmed publisher
|
An D, Fujiki R, Iannitelli D, Smerdon J, Maity S, Rose M, et al. Stem cell-derived cranial and spinal motor neurons reveal proteostatic differences between ALS resistant and sensitive motor neurons. elife. 2019;8: pubmed publisher
|
Kozlova N, Mennerich D, Samoylenko A, Dimova E, Koivunen P, Biterova E, et al. The pro-oncogenic adaptor CIN85 acts as an inhibitory binding partner of hypoxia-inducible factor prolyl hydroxylase 2. Cancer Res. 2019;: pubmed publisher
|
Park J, Lee S, Jeong H, Kang M, Van Haute L, Minczuk M, et al. The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination. Nucleic Acids Res. 2019;47:7078-7093 pubmed publisher
|
Fazi B, Proserpio C, Galardi S, Annesi F, Cola M, Mangiola A, et al. The Expression of the Chemokine CXCL14 Correlates with Several Aggressive Aspects of Glioblastoma and Promotes Key Properties of Glioblastoma Cells. Int J Mol Sci. 2019;20: pubmed publisher
|
Kim L, Hong S, Choi K. Protein phosphatase 2A interacts with Verthandi/Rad21 to regulate mitosis and organ development in Drosophila. Sci Rep. 2019;9:7624 pubmed publisher
|
Paquin K, Mamrak N, Garzon J, Cantres Velez J, Azzinaro P, Vuono E, et al. FANCD2 binding to H4K20me2 via a methyl-binding domain is essential for efficient DNA crosslink repair. Mol Cell Biol. 2019;: pubmed publisher
|
Bailetti A, Negrón Piñeiro L, Dhruva V, Harsh S, Lu S, Bosula A, et al. Enhancer of Polycomb and the Tip60 complex repress hematological tumor initiation by negatively regulating JAK/STAT pathway activity. Dis Model Mech. 2019;12: pubmed publisher
|
Hickey S, Berto S, Konopka G. Chromatin Decondensation by FOXP2 Promotes Human Neuron Maturation and Expression of Neurodevelopmental Disease Genes. Cell Rep. 2019;27:1699-1711.e9 pubmed publisher
|
Tufi R, Gleeson T, von Stockum S, Hewitt V, Lee J, Terriente Félix A, et al. Comprehensive Genetic Characterization of Mitochondrial Ca2+ Uniporter Components Reveals Their Different Physiological Requirements In Vivo. Cell Rep. 2019;27:1541-1550.e5 pubmed publisher
|
Hampton Smith R, Davenport B, Nagarajan Y, Peet D. The conservation and functionality of the oxygen-sensing enzyme Factor Inhibiting HIF (FIH) in non-vertebrates. PLoS ONE. 2019;14:e0216134 pubmed publisher
|
Sales E, Heckman E, Warren T, Doe C. Regulation of subcellular dendritic synapse specificity by axon guidance cues. elife. 2019;8: pubmed publisher
|
Rommelaere S, Boquete J, Piton J, Kondo S, Lemaitre B. The Exchangeable Apolipoprotein Nplp2 Sustains Lipid Flow and Heat Acclimation in Drosophila. Cell Rep. 2019;27:886-899.e6 pubmed publisher
|
Fukumoto T, Zhu H, Nacarelli T, Karakashev S, Fatkhutdinov N, Wu S, et al. N6-Methylation of Adenosine of FZD10 mRNA Contributes to PARP Inhibitor Resistance. Cancer Res. 2019;79:2812-2820 pubmed publisher
|
Chu B, Kon N, Chen D, Li T, Liu T, Jiang L, et al. ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway. Nat Cell Biol. 2019;21:579-591 pubmed publisher
|
Chua N, Hart Smith G, Brown A. Non-canonical ubiquitination of the cholesterol-regulated degron of squalene monooxygenase. J Biol Chem. 2019;294:8134-8147 pubmed publisher
|
Garg R, Jackson C, Rahman M, Khan A, Lewin A, McFadden G. Myxoma virus M013 protein antagonizes NF-κB and inflammasome pathways via distinct structural motifs. J Biol Chem. 2019;294:8480-8489 pubmed publisher
|
Yu J, Yan Y, Luan X, Qiao C, Liu Y, Zhao D, et al. Srlp is crucial for the self-renewal and differentiation of germline stem cells via RpL6 signals in Drosophila testes. Cell Death Dis. 2019;10:294 pubmed publisher
|
Deng X, Mettelman R, O Brien A, Thompson J, O Brien T, Baker S. Analysis of Coronavirus Temperature-Sensitive Mutants Reveals an Interplay between the Macrodomain and Papain-Like Protease Impacting Replication and Pathogenesis. J Virol. 2019;93: pubmed publisher
|
Du T, Dewey J, Wagner E, Cui R, Heo J, Park J, et al. LMO7 deficiency reveals the significance of the cuticular plate for hearing function. Nat Commun. 2019;10:1117 pubmed publisher
|
Han Y, Branon T, Martell J, Boassa D, Shechner D, Ellisman M, et al. Directed Evolution of Split APEX2 Peroxidase. ACS Chem Biol. 2019;14:619-635 pubmed publisher
|
Tye B, Commins N, Ryazanova L, Wühr M, Springer M, Pincus D, et al. Proteotoxicity from aberrant ribosome biogenesis compromises cell fitness. elife. 2019;8: pubmed publisher
|
Vatsa N, Kumar V, Singh B, Kumar S, Sharma A, Jana N. Down-Regulation of miRNA-708 Promotes Aberrant Calcium Signaling by Targeting Neuronatin in a Mouse Model of Angelman Syndrome. Front Mol Neurosci. 2019;12:35 pubmed publisher
|
Gopalakrishnan R, Marr S, Kingston R, Winston F. A conserved genetic interaction between Spt6 and Set2 regulates H3K36 methylation. Nucleic Acids Res. 2019;47:3888-3903 pubmed publisher
|
Kim A, Choi K. TRiC/CCT chaperonins are essential for organ growth by interacting with insulin/TOR signaling in Drosophila. Oncogene. 2019;38:4739-4754 pubmed publisher
|
Mitsuhashi H, Homma S, Beermann M, Ishimaru S, Takeda H, Yu B, et al. Efficient system for upstream mRNA trans-splicing to generate covalent, head-to-tail, protein multimers. Sci Rep. 2019;9:2274 pubmed publisher
|
Kunova Bosakova M, Nita A, Gregor T, Varecha M, Gudernová I, Fafilek B, et al. Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase. Proc Natl Acad Sci U S A. 2019;: pubmed publisher
|
Bertran M, Mouilleron S, Zhou Y, Bajaj R, Uliana F, Kumar G, et al. ASPP proteins discriminate between PP1 catalytic subunits through their SH3 domain and the PP1 C-tail. Nat Commun. 2019;10:771 pubmed publisher
|
Chen I, Moriyama M, Chang M, Ichinohe T. Severe Acute Respiratory Syndrome Coronavirus Viroporin 3a Activates the NLRP3 Inflammasome. Front Microbiol. 2019;10:50 pubmed publisher
|
Neurohr G, Terry R, Lengefeld J, Bonney M, Brittingham G, Moretto F, et al. Excessive Cell Growth Causes Cytoplasm Dilution And Contributes to Senescence. Cell. 2019;: pubmed publisher
|
Lee H, Willi M, Smith H, Miller S, Liu D, Liu C, et al. Simultaneous targeting of linked loci in mouse embryos using base editing. Sci Rep. 2019;9:1662 pubmed publisher
|
Kol M, Williams B, Toombs Ruane H, Franquelim H, Korneev S, Schroeer C, et al. Optical manipulation of sphingolipid biosynthesis using photoswitchable ceramides. elife. 2019;8: pubmed publisher
|
Fischer M, Jonkers W, Glass N. Integration of Self and Non-self Recognition Modulates Asexual Cell-to-Cell Communication in Neurospora crassa. Genetics. 2019;211:1255-1267 pubmed publisher
|
Ashley J, Sorrentino V, Lobb Rabe M, Nagarkar Jaiswal S, Tan L, Xu S, et al. Transsynaptic interactions between IgSF proteins DIP-α and Dpr10 are required for motor neuron targeting specificity. elife. 2019;8: pubmed publisher
|
Cheng S, Ashley J, Kurleto J, Lobb Rabe M, Park Y, Carrillo R, et al. Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila. elife. 2019;8: pubmed publisher
|
Spence E, Dube S, Uezu A, Locke M, Soderblom E, Soderling S. In vivo proximity proteomics of nascent synapses reveals a novel regulator of cytoskeleton-mediated synaptic maturation. Nat Commun. 2019;10:386 pubmed publisher
|
Haidar M, Asselbergh B, Adriaenssens E, de Winter V, Timmermans J, Auer Grumbach M, et al. Neuropathy-causing mutations in HSPB1 impair autophagy by disturbing the formation of SQSTM1/p62 bodies. Autophagy. 2019;15:1051-1068 pubmed publisher
|
Jiménez M, Urtasun R, Elizalde M, Azkona M, Latasa M, Uriarte I, et al. Splicing events in the control of genome integrity: role of SLU7 and truncated SRSF3 proteins. Nucleic Acids Res. 2019;47:3450-3466 pubmed publisher
|
Phillips C, Tsai C, Tsai M. The conserved aspartate ring of MCU mediates MICU1 binding and regulation in the mitochondrial calcium uniporter complex. elife. 2019;8: pubmed publisher
|
Sato K, Ito H, Yokoyama A, Toba G, Yamamoto D. Partial proteasomal degradation of Lola triggers the male-to-female switch of a dimorphic courtship circuit. Nat Commun. 2019;10:166 pubmed publisher
|
González de Cózar J, Gerards M, Teeri E, George J, Dufour E, Jacobs H, et al. RNase H1 promotes replication fork progression through oppositely transcribed regions of Drosophila mitochondrial DNA. J Biol Chem. 2019;294:4331-4344 pubmed publisher
|
Salehi Tabar R, Memari B, Wong H, Dimitrov V, Rochel N, White J. The Tumor Suppressor FBW7 and the Vitamin D Receptor Are Mutual Cofactors in Protein Turnover and Transcriptional Regulation. Mol Cancer Res. 2019;17:709-719 pubmed publisher
|
Aggarwal S, Gabrovsek L, Langeberg L, Golkowski M, Ong S, Smith F, et al. Depletion of dAKAP1-protein kinase A signaling islands from the outer mitochondrial membrane alters breast cancer cell metabolism and motility. J Biol Chem. 2019;294:3152-3168 pubmed publisher
|
Sawyer E, Joshi P, Jorgensen V, Yunus J, Berchowitz L, Unal E. Developmental regulation of an organelle tether coordinates mitochondrial remodeling in meiosis. J Cell Biol. 2019;218:559-579 pubmed publisher
|
Cummins N, Tweedie A, Zuryn S, Bertran Gonzalez J, Götz J. Disease-associated tau impairs mitophagy by inhibiting Parkin translocation to mitochondria. EMBO J. 2019;38: pubmed publisher
|
Zhou H, Zhang R, Anand P, Stomberski C, Qian Z, Hausladen A, et al. Metabolic reprogramming by the S-nitroso-CoA reductase system protects against kidney injury. Nature. 2019;565:96-100 pubmed publisher
|
Fauster A, Rebsamen M, Willmann K, César Razquin A, Girardi E, Bigenzahn J, et al. Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking. Cell Death Differ. 2019;26:1138-1155 pubmed publisher
|
Aviram R, Zaffryar Eilot S, Hubmacher D, Grunwald H, Maki J, Myllyharju J, et al. Interactions between lysyl oxidases and ADAMTS proteins suggest a novel crosstalk between two extracellular matrix families. Matrix Biol. 2019;75-76:114-125 pubmed publisher
|
Okamoto K, Ohishi T, Kuroiwa M, Iemura S, Natsume T, Seimiya H. MERIT40-dependent recruitment of tankyrase to damaged DNA and its implication for cell sensitivity to DNA-damaging anticancer drugs. Oncotarget. 2018;9:35844-35855 pubmed publisher
|
Bowie E, Norris R, Anderson K, Goetz S. Spinocerebellar ataxia type 11-associated alleles of Ttbk2 dominantly interfere with ciliogenesis and cilium stability. PLoS Genet. 2018;14:e1007844 pubmed publisher
|
O Neill A, Kyrousi C, Klaus J, Leventer R, Kirk E, Fry A, et al. A Primate-Specific Isoform of PLEKHG6 Regulates Neurogenesis and Neuronal Migration. Cell Rep. 2018;25:2729-2741.e6 pubmed publisher
|
Jeon Y, Kim T, Park D, Nuovo G, Rhee S, Joshi P, et al. miRNA-mediated TUSC3 deficiency enhances UPR and ERAD to promote metastatic potential of NSCLC. Nat Commun. 2018;9:5110 pubmed publisher
|
Dubbury S, Boutz P, Sharp P. CDK12 regulates DNA repair genes by suppressing intronic polyadenylation. Nature. 2018;564:141-145 pubmed publisher
|
Benhalevy D, Anastasakis D, Hafner M. Proximity-CLIP provides a snapshot of protein-occupied RNA elements in subcellular compartments. Nat Methods. 2018;15:1074-1082 pubmed publisher
|
Nojima T, Tellier M, Foxwell J, Ribeiro de Almeida C, Tan Wong S, Dhir S, et al. Deregulated Expression of Mammalian lncRNA through Loss of SPT6 Induces R-Loop Formation, Replication Stress, and Cellular Senescence. Mol Cell. 2018;72:970-984.e7 pubmed publisher
|
Singh A, Khare P, Obaid A, Conlon K, Basrur V, Depinho R, et al. SUMOylation of ROR-γt inhibits IL-17 expression and inflammation via HDAC2. Nat Commun. 2018;9:4515 pubmed publisher
|
Gibb N, Lazic S, Yuan X, Deshwar A, Leslie M, Wilson M, et al. Hey2 regulates the size of the cardiac progenitor pool during vertebrate heart development. Development. 2018;145: pubmed publisher
|
Zhao N, Liu C, Van Ingelgom A, Linares C, Kurti A, Knight J, et al. APOE ε2 is associated with increased tau pathology in primary tauopathy. Nat Commun. 2018;9:4388 pubmed publisher
|
Doris S, Chuang J, Viktorovskaya O, Murawska M, Spatt D, Churchman L, et al. Spt6 Is Required for the Fidelity of Promoter Selection. Mol Cell. 2018;72:687-699.e6 pubmed publisher
|
Vazquez M, Toro C, Castellano J, Ruiz Pino F, Roa J, Beiroa D, et al. SIRT1 mediates obesity- and nutrient-dependent perturbation of pubertal timing by epigenetically controlling Kiss1 expression. Nat Commun. 2018;9:4194 pubmed publisher
|
Tsusaka T, Kikuchi M, Shimazu T, Suzuki T, Sohtome Y, Akakabe M, et al. Tri-methylation of ATF7IP by G9a/GLP recruits the chromodomain protein MPP8. Epigenetics Chromatin. 2018;11:56 pubmed publisher
|
Di H, Morantz E, Sadhwani H, Madden J, Brinton M. Insertion position as well as the inserted TRS and gene sequences differentially affect the retention of foreign gene expression by simian hemorrhagic fever virus (SHFV). Virology. 2018;525:150-160 pubmed publisher
|
Jiang Z, Yue W, Chen L, Sheng Y, Yau K. Cyclic-Nucleotide- and HCN-Channel-Mediated Phototransduction in Intrinsically Photosensitive Retinal Ganglion Cells. Cell. 2018;175:652-664.e12 pubmed publisher
|
Boese C, Nye J, Buster D, McLamarrah T, Byrnes A, Slep K, et al. Asterless is a Polo-like kinase 4 substrate that both activates and inhibits kinase activity depending on its phosphorylation state. Mol Biol Cell. 2018;29:2874-2886 pubmed publisher
|
Li Z, Ning S, Su X, Liu X, Wang H, Liu Y, et al. Enterovirus 71 antagonizes the inhibition of the host intrinsic antiviral factor A3G. Nucleic Acids Res. 2018;46:11514-11527 pubmed publisher
|
Mouly L, Mamouni K, Gence R, Cristini A, Cherier J, Castinel A, et al. PARP-1-dependent RND1 transcription induced by topoisomerase I cleavage complexes confers cellular resistance to camptothecin. Cell Death Dis. 2018;9:931 pubmed publisher
|
Johnson T, Costa A, Ferguson A, Frezza C. Fumarate hydratase loss promotes mitotic entry in the presence of DNA damage after ionising radiation. Cell Death Dis. 2018;9:913 pubmed publisher
|
Zhang J, Guan X, Li Q, Meredith A, Pan H, Yan J. Glutamate-activated BK channel complexes formed with NMDA receptors. Proc Natl Acad Sci U S A. 2018;115:E9006-E9014 pubmed publisher
|
Ji S, Samara N, Revoredo L, Zhang L, Tran D, Muirhead K, et al. A molecular switch orchestrates enzyme specificity and secretory granule morphology. Nat Commun. 2018;9:3508 pubmed publisher
|
Otto N, Marelja Z, Schoofs A, Kranenburg H, Bittern J, Yildirim K, et al. The sulfite oxidase Shopper controls neuronal activity by regulating glutamate homeostasis in Drosophila ensheathing glia. Nat Commun. 2018;9:3514 pubmed publisher
|
Chakrabarty P, Li A, Ladd T, Strickland M, Koller E, Burgess J, et al. TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer's disease. J Exp Med. 2018;215:2247-2264 pubmed publisher
|
Lee S, Singh I, Tisdale S, Abdel Wahab O, Leslie C, Mayr C. Widespread intronic polyadenylation inactivates tumour suppressor genes in leukaemia. Nature. 2018;561:127-131 pubmed publisher
|
Kaci A, Keindl M, Solheim M, Njølstad P, Bjørkhaug L, Aukrust I. The E3 SUMO ligase PIAS? is a novel interaction partner regulating the activity of diabetes associated hepatocyte nuclear factor-1?. Sci Rep. 2018;8:12780 pubmed publisher
|
Li J, Guajardo R, Xu C, Wu B, Li H, Li T, et al. Stepwise wiring of the Drosophila olfactory map requires specific Plexin B levels. elife. 2018;7: pubmed publisher
|
Lang J, Barber A, Biggins S. An assay for de novo kinetochore assembly reveals a key role for the CENP-T pathway in budding yeast. elife. 2018;7: pubmed publisher
|
Maksimov V, Oya E, Tanaka M, Kawaguchi T, Hachisuka A, Ekwall K, et al. The binding of Chp2's chromodomain to methylated H3K9 is essential for Chp2's role in heterochromatin assembly in fission yeast. PLoS ONE. 2018;13:e0201101 pubmed publisher
|
Wang P, Ye Z, Deng J, Siu K, Gao W, Chaudhary V, et al. Inhibition of AIM2 inflammasome activation by a novel transcript isoform of IFI16. EMBO Rep. 2018;19: pubmed publisher
|
Zhang P, Lu H, Peixoto R, Pines M, Ge Y, Oku S, et al. Heparan Sulfate Organizes Neuronal Synapses through Neurexin Partnerships. Cell. 2018;174:1450-1464.e23 pubmed publisher
|
Wang B, Underwood R, Kamath A, Britain C, McFerrin M, McLean P, et al. 14-3-3 Proteins Reduce Cell-to-Cell Transfer and Propagation of Pathogenic α-Synuclein. J Neurosci. 2018;38:8211-8232 pubmed publisher
|
Lommel M, Strompen J, Hellewell A, Balasubramanian G, Christofidou E, Thomson A, et al. Hydra Mesoglea Proteome Identifies Thrombospondin as a Conserved Component Active in Head Organizer Restriction. Sci Rep. 2018;8:11753 pubmed publisher
|
Yoon S, Kook T, Min H, Kwon D, Cho Y, Kim M, et al. PP2A negatively regulates the hypertrophic response by dephosphorylating HDAC2 S394 in the heart. Exp Mol Med. 2018;50:83 pubmed publisher
|
Schleicher T, Yang J, Freudzon M, Rembisz A, Craft S, Hamilton M, et al. A mosquito salivary gland protein partially inhibits Plasmodium sporozoite cell traversal and transmission. Nat Commun. 2018;9:2908 pubmed publisher
|
Chiu H, Chiu H, Yang C, Lee Y, Chiu F, Kuo H, et al. Inhibition of Japanese encephalitis virus infection by the host zinc-finger antiviral protein. PLoS Pathog. 2018;14:e1007166 pubmed publisher
|
Fang L, Teng H, Wang Y, Liao G, Weng L, Li Y, et al. SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis. Cancer Cell. 2018;34:103-118.e9 pubmed publisher
|
Masuko K, Furuhashi H, Komaba K, Numao E, Nakajima R, Fuse N, et al. Nuclear Lamin is required for Winged Eye-mediated transdetermination of Drosophila imaginal disc. Genes Cells. 2018;: pubmed publisher
|
Piacentino M, Bronner M. Intracellular attenuation of BMP signaling via CKIP-1/Smurf1 is essential during neural crest induction. PLoS Biol. 2018;16:e2004425 pubmed publisher
|
Verma N, Hurlburt A, Wolfe A, Kim M, Kang Y, Kang J, et al. Bdp1 interacts with SNAPc bound to a U6, but not U1, snRNA gene promoter element to establish a stable protein-DNA complex. FEBS Lett. 2018;592:2489-2498 pubmed publisher
|
Varland S, Arnesen T. Investigating the functionality of a ribosome-binding mutant of NAA15 using Saccharomyces cerevisiae. BMC Res Notes. 2018;11:404 pubmed publisher
|
Lin G, Lee P, Chen K, Mao D, Tan K, Zuo Z, et al. Phospholipase PLA2G6, a Parkinsonism-Associated Gene, Affects Vps26 and Vps35, Retromer Function, and Ceramide Levels, Similar to ?-Synuclein Gain. Cell Metab. 2018;: pubmed publisher
|
Chen S, Fragoza R, Klei L, Liu Y, Wang J, Roeder K, et al. An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders. Nat Genet. 2018;50:1032-1040 pubmed publisher
|
Wang H, Li S, Wang J, Chen S, Sun X, Wu Q. N-glycosylation in the protease domain of trypsin-like serine proteases mediates calnexin-assisted protein folding. elife. 2018;7: pubmed publisher
|
T Abshire E, Chasseur J, Bohn J, Del Rizzo P, Freddolino P, Goldstrohm A, et al. The structure of human Nocturnin reveals a conserved ribonuclease domain that represses target transcript translation and abundance in cells. Nucleic Acids Res. 2018;46:6257-6270 pubmed publisher
|
Bao L, Chen Y, Lai H, Wu S, Wang J, Hatanpaa K, et al. Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration. Nucleic Acids Res. 2018;46:6576-6591 pubmed publisher
|
Fernandez L, Sánchez Martínez R, Vargas T, Herranz J, Martin Hernandez R, Mendiola M, et al. The role of glycosyltransferase enzyme GCNT3 in colon and ovarian cancer prognosis and chemoresistance. Sci Rep. 2018;8:8485 pubmed publisher
|
Gupta A, Evans R, Koch L, Littleton A, Biggins S. Purification of kinetochores from the budding yeast Saccharomyces cerevisiae. Methods Cell Biol. 2018;144:349-370 pubmed publisher
|
Kasowitz S, Ma J, Anderson S, Leu N, Xu Y, Gregory B, et al. Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development. PLoS Genet. 2018;14:e1007412 pubmed publisher
|
Lebrun M, Lambert J, Riva L, Thelen N, Rambout X, Blondeau C, et al. Varicella-Zoster Virus ORF9p Binding to Cellular Adaptor Protein Complex 1 Is Important for Viral Infectivity. J Virol. 2018;92: pubmed publisher
|
Pan J, Meyers R, Michel B, Mashtalir N, Sizemore A, Wells J, et al. Interrogation of Mammalian Protein Complex Structure, Function, and Membership Using Genome-Scale Fitness Screens. Cell Syst. 2018;6:555-568.e7 pubmed publisher
|
Jordán Pla A, Yu S, Waldholm J, Källman T, Ostlund Farrants A, Visa N. SWI/SNF regulates half of its targets without the need of ATP-driven nucleosome remodeling by Brahma. BMC Genomics. 2018;19:367 pubmed publisher
|
Alapin J, Dines M, Vassiliev M, Tamir T, Ram A, Locke C, et al. Activation of EphB2 Forward Signaling Enhances Memory Consolidation. Cell Rep. 2018;23:2014-2025 pubmed publisher
|
Horard B, Sapey Triomphe L, Bonnefoy E, Loppin B. ASF1 is required to load histones on the HIRA complex in preparation of paternal chromatin assembly at fertilization. Epigenetics Chromatin. 2018;11:19 pubmed publisher
|
Shen J, Ju Z, Zhao W, Wang L, Peng Y, Ge Z, et al. ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade. Nat Med. 2018;24:556-562 pubmed publisher
|
Vasiliauskaite L, Berrens R, Ivanova I, Carrieri C, Reik W, Enright A, et al. Defective germline reprogramming rewires the spermatogonial transcriptome. Nat Struct Mol Biol. 2018;25:394-404 pubmed publisher
|
Matsumoto N, Sekiya M, Tohyama K, Ishiyama Matsuura E, Sun Wada G, Wada Y, et al. Essential Role of the a3 Isoform of V-ATPase in Secretory Lysosome Trafficking via Rab7 Recruitment. Sci Rep. 2018;8:6701 pubmed publisher
|
Tan K, Haelterman N, Kwartler C, Regalado E, Lee P, Nagarkar Jaiswal S, et al. Ari-1 Regulates Myonuclear Organization Together with Parkin and Is Associated with Aortic Aneurysms. Dev Cell. 2018;45:226-244.e8 pubmed publisher
|
Ichiakwa Y, Kaufman P. Biochemical Analysis of Dimethyl Suberimidate-crosslinked Yeast Nucleosomes. Bio Protoc. 2018;8: pubmed publisher
|
Engelke A, Gonsberg A, Thapa S, Jung S, Ulbrich S, Seidel R, et al. Dimerization of the cellular prion protein inhibits propagation of scrapie prions. J Biol Chem. 2018;293:8020-8031 pubmed publisher
|
Song H, Feng X, Zhang M, Jin X, Xu X, Wang L, et al. Crosstalk between lysine methylation and phosphorylation of ATG16L1 dictates the apoptosis of hypoxia/reoxygenation-induced cardiomyocytes. Autophagy. 2018;14:825-844 pubmed publisher
|
Mitsuhashi H, Ishimaru S, Homma S, Yu B, Honma Y, Beermann M, et al. Functional domains of the FSHD-associated DUX4 protein. Biol Open. 2018;7: pubmed publisher
|
Zhang H, Zhu Q, Cui J, Wang Y, Chen M, Guo X, et al. Structure and evolution of the Fam20 kinases. Nat Commun. 2018;9:1218 pubmed publisher
|
Mazel Sanchez B, Boal Carvalho I, Silva F, Dijkman R, Schmolke M. H5N1 Influenza A Virus PB1-F2 Relieves HAX-1-Mediated Restriction of Avian Virus Polymerase PA in Human Lung Cells. J Virol. 2018;92: pubmed publisher
|
Zhang L, Köhler S, Rillo Bohn R, Dernburg A. A compartmentalized signaling network mediates crossover control in meiosis. elife. 2018;7: pubmed publisher
|
Kramer N, Haney M, Morgens D, Jovicic A, Couthouis J, Li A, et al. CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity. Nat Genet. 2018;50:603-612 pubmed publisher
|
Poirier E, Goic B, Tomé Poderti L, Frangeul L, Boussier J, Gausson V, et al. Dicer-2-Dependent Generation of Viral DNA from Defective Genomes of RNA Viruses Modulates Antiviral Immunity in Insects. Cell Host Microbe. 2018;23:353-365.e8 pubmed publisher
|
Lee K, Cho K, Kim B, Jang I, Nam K, Kwon Y, et al. Inflammation-Modulated Metabolic Reprogramming Is Required for DUOX-Dependent Gut Immunity in Drosophila. Cell Host Microbe. 2018;23:338-352.e5 pubmed publisher
|
Bussey K, Lau U, Schumann S, Gallo A, Osbelt L, Stempel M, et al. The interferon-stimulated gene product oligoadenylate synthetase-like protein enhances replication of Kaposi's sarcoma-associated herpesvirus (KSHV) and interacts with the KSHV ORF20 protein. PLoS Pathog. 2018;14:e1006937 pubmed publisher
|
Gao Y, Chang M, McKay D, Na N, Zhou B, Yaeger R, et al. Allele-Specific Mechanisms of Activation of MEK1 Mutants Determine Their Properties. Cancer Discov. 2018;8:648-661 pubmed publisher
|
Iliadi K, Gluscencova O, Iliadi N, Boulianne G. Mutations in the Drosophila homolog of human PLA2G6 give rise to age-dependent loss of psychomotor activity and neurodegeneration. Sci Rep. 2018;8:2939 pubmed publisher
|
Seguel A, Jelenska J, Herrera Vásquez A, Marr S, Joyce M, Gagesch K, et al. PROHIBITIN3 Forms Complexes with ISOCHORISMATE SYNTHASE1 to Regulate Stress-Induced Salicylic Acid Biosynthesis in Arabidopsis. Plant Physiol. 2018;176:2515-2531 pubmed publisher
|
Leibowitz B, Yang L, Wei L, Buchanan M, Rachid M, Parise R, et al. Targeting p53-dependent stem cell loss for intestinal chemoprotection. Sci Transl Med. 2018;10: pubmed publisher
|
Aoki H, Yamamoto E, Takasawa A, Niinuma T, Yamano H, Harada T, et al. Epigenetic silencing of SMOC1 in traditional serrated adenoma and colorectal cancer. Oncotarget. 2018;9:4707-4721 pubmed publisher
|
Hasegawa Minato J, Toyoshima M, Ishibashi M, Zhang X, Shigeta S, Grandori C, et al. Novel cooperative pathway of c-Myc and Furin, a pro-protein convertase, in cell proliferation as a therapeutic target in ovarian cancers. Oncotarget. 2018;9:3483-3496 pubmed publisher
|
Tacchelly Benites O, Wang Z, Yang E, Benchabane H, Tian A, Randall M, et al. Axin phosphorylation in both Wnt-off and Wnt-on states requires the tumor suppressor APC. PLoS Genet. 2018;14:e1007178 pubmed publisher
|
Limsakul P, Peng Q, Wu Y, Allen M, Liang J, Remacle A, et al. Directed Evolution to Engineer Monobody for FRET Biosensor Assembly and Imaging at Live-Cell Surface. Cell Chem Biol. 2018;25:370-379.e4 pubmed publisher
|
Logue J, Cartagena Rivera A, Chadwick R. c-Src activity is differentially required by cancer cell motility modes. Oncogene. 2018;37:2104-2121 pubmed publisher
|
Korge S, Maier B, Brüning F, Ehrhardt L, Korte T, Mann M, et al. The non-classical nuclear import carrier Transportin 1 modulates circadian rhythms through its effect on PER1 nuclear localization. PLoS Genet. 2018;14:e1007189 pubmed publisher
|
Molinarolo S, Lee S, Leisle L, Lueck J, Granata D, Carnevale V, et al. Cross-kingdom auxiliary subunit modulation of a voltage-gated sodium channel. J Biol Chem. 2018;293:4981-4992 pubmed publisher
|
Astigarraga S, DOUTHIT J, Tarnogorska D, Creamer M, Mano O, Clark D, et al. Drosophila Sidekick is required in developing photoreceptors to enable visual motion detection. Development. 2018;145: pubmed publisher
|
Lyraki R, Lokaj M, Soares D, Little A, Vermeren M, Marsh J, et al. Characterization of a novel RP2-OSTF1 interaction and its implication for actin remodelling. J Cell Sci. 2018;131: pubmed publisher
|
Kunova Bosakova M, Varecha M, Hampl M, Durán I, Nita A, Buchtová M, et al. Regulation of ciliary function by fibroblast growth factor signaling identifies FGFR3-related disorders achondroplasia and thanatophoric dysplasia as ciliopathies. Hum Mol Genet. 2018;27:1093-1105 pubmed publisher
|
Koh A, Miller E, Buenrostro J, Moskowitz D, Wang J, Greenleaf W, et al. Rapid chromatin repression by Aire provides precise control of immune tolerance. Nat Immunol. 2018;19:162-172 pubmed publisher
|
Shi B, Xue J, Zhou J, Kasowitz S, Zhang Y, Liang G, et al. MORC2B is essential for meiotic progression and fertility. PLoS Genet. 2018;14:e1007175 pubmed publisher
|
Lee J, Mand M, Kao C, Zhou Y, Ryu S, Richards A, et al. ATM directs DNA damage responses and proteostasis via genetically separable pathways. Sci Signal. 2018;11: pubmed publisher
|
Cronin J, Loftus S, Baxter L, Swatkoski S, Gucek M, Pavan W. Identification and functional analysis of SOX10 phosphorylation sites in melanoma. PLoS ONE. 2018;13:e0190834 pubmed publisher
|
Kidana K, Tatebe T, Ito K, Hara N, Kakita A, Saito T, et al. Loss of kallikrein-related peptidase 7 exacerbates amyloid pathology in Alzheimer's disease model mice. EMBO Mol Med. 2018;10: pubmed publisher
|
Ding D, Bergmaier P, Sachs P, Klangwart M, Rückert T, Bartels N, et al. The CUE1 domain of the SNF2-like chromatin remodeler SMARCAD1 mediates its association with KRAB-associated protein 1 (KAP1) and KAP1 target genes. J Biol Chem. 2018;293:2711-2724 pubmed publisher
|
Riedel F, Galindo A, Muschalik N, Munro S. The two TRAPP complexes of metazoans have distinct roles and act on different Rab GTPases. J Cell Biol. 2018;217:601-617 pubmed publisher
|
Chiang C, Pauli E, Biryukov J, Feister K, Meng M, White E, et al. The Human Papillomavirus E6 Oncoprotein Targets USP15 and TRIM25 To Suppress RIG-I-Mediated Innate Immune Signaling. J Virol. 2018;92: pubmed publisher
|
Norppa A, Kauppala T, Heikkinen H, Verma B, Iwai H, Frilander M. Mutations in the U11/U12-65K protein associated with isolated growth hormone deficiency lead to structural destabilization and impaired binding of U12 snRNA. RNA. 2018;24:396-409 pubmed publisher
|
Howley B, Link L, Grelet S, El Sabban M, Howe P. A CREB3-regulated ER-Golgi trafficking signature promotes metastatic progression in breast cancer. Oncogene. 2018;37:1308-1325 pubmed publisher
|
Liu C, Zhang C, Zhou Y, Wong W, Lee L, Ong W, et al. APP upregulation contributes to retinal ganglion cell degeneration via JNK3. Cell Death Differ. 2018;25:661-676 pubmed publisher
|
Kashlan O, Kinlough C, MYERBURG M, Shi S, Chen J, Blobner B, et al. N-linked glycans are required on epithelial Na+ channel subunits for maturation and surface expression. Am J Physiol Renal Physiol. 2018;314:F483-F492 pubmed publisher
|
Bhide G, Zapater J, Colley K. Autopolysialylation of polysialyltransferases is required for polysialylation and polysialic acid chain elongation on select glycoprotein substrates. J Biol Chem. 2018;293:701-716 pubmed publisher
|
Chen S, Wang H, Li H, Zhang Y, Wu Q. Functional analysis of corin protein domains required for PCSK6-mediated activation. Int J Biochem Cell Biol. 2018;94:31-39 pubmed publisher
|
Haupt J, Xu M, Shore E. Variable signaling activity by FOP ACVR1 mutations. Bone. 2018;109:232-240 pubmed publisher
|
Zhang X, Kitatani K, Toyoshima M, Ishibashi M, Usui T, Minato J, et al. Ceramide Nanoliposomes as a MLKL-Dependent, Necroptosis-Inducing, Chemotherapeutic Reagent in Ovarian Cancer. Mol Cancer Ther. 2018;17:50-59 pubmed publisher
|
Broix L, Asselin L, Silva C, Ivanova E, Tilly P, Gilet J, et al. Ciliogenesis and cell cycle alterations contribute to KIF2A-related malformations of cortical development. Hum Mol Genet. 2018;27:224-238 pubmed publisher
|
Zhang X, Choi P, FRANCIS J, Gao G, Campbell J, Ramachandran A, et al. Somatic Superenhancer Duplications and Hotspot Mutations Lead to Oncogenic Activation of the KLF5 Transcription Factor. Cancer Discov. 2018;8:108-125 pubmed publisher
|
Hammond J, Zhou L, Lamichhane R, Chu H, Millar D, Gerace L, et al. A Survey of DDX21 Activity During Rev/RRE Complex Formation. J Mol Biol. 2018;430:537-553 pubmed publisher
|
Gudernová I, Balek L, Varecha M, Kucerova J, Kunova Bosakova M, Fafilek B, et al. Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480. Oncotarget. 2017;8:109319-109331 pubmed publisher
|
Chen R, Xu M, Nagati J, Garcia J. Coordinate regulation of stress signaling and epigenetic events by Acss2 and HIF-2 in cancer cells. PLoS ONE. 2017;12:e0190241 pubmed publisher
|
Biscontin A, Wallach T, Sales G, Grudziecki A, Janke L, Sartori E, et al. Functional characterization of the circadian clock in the Antarctic krill, Euphausia superba. Sci Rep. 2017;7:17742 pubmed publisher
|
Huang T, Niesman P, Arasu D, Lee D, De La Cruz A, Callejas A, et al. Tracing neuronal circuits in transgenic animals by transneuronal control of transcription (TRACT). elife. 2017;6: pubmed publisher
|
Scortegagna M, Berthon A, Settas N, Giannakou A, Garcia G, Li J, et al. The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion. JCI Insight. 2017;2: pubmed publisher
|
Kim M, Morales L, Baek M, Slaga T, DiGiovanni J, Kim D. UVB-induced nuclear translocation of TC-PTP by AKT/14-3-3? axis inhibits keratinocyte survival and proliferation. Oncotarget. 2017;8:90674-90692 pubmed publisher
|
Ovsiy I, Riabov V, Manousaridis I, Michel J, Moganti K, Yin S, et al. IL-4 driven transcription factor FoxQ1 is expressed by monocytes in atopic dermatitis and stimulates monocyte migration. Sci Rep. 2017;7:16847 pubmed publisher
|
Takagi S, Cocanougher B, Niki S, Miyamoto D, Kohsaka H, Kazama H, et al. Divergent Connectivity of Homologous Command-like Neurons Mediates Segment-Specific Touch Responses in Drosophila. Neuron. 2017;96:1373-1387.e6 pubmed publisher
|
Vazquez Fonseca L, Doimo M, Calderan C, Desbats M, Acosta M, Cerqua C, et al. Mutations in COQ8B (ADCK4) found in patients with steroid resistant nephrotic syndrome alter COQ8B function. Hum Mutat. 2017;: pubmed publisher
|
Kim M, Wang W, Sánchez M, Coukos R, von Zastrow M, Ting A. Time-gated detection of protein-protein interactions with transcriptional readout. elife. 2017;6: pubmed publisher
|
Usui N, Araujo D, Kulkarni A, Co M, Ellegood J, Harper M, et al. Foxp1 regulation of neonatal vocalizations via cortical development. Genes Dev. 2017;31:2039-2055 pubmed publisher
|
Casey A, Moehlman A, Zhang J, Servage K, KRAMER H, Orth K. Fic-mediated deAMPylation is not dependent on homodimerization and rescues toxic AMPylation in flies. J Biol Chem. 2017;292:21193-21204 pubmed publisher
|
Liu J, Rao Y, Cheung M, Hui M, Wu M, Chan L, et al. Asymmetric localization of DLC1 defines avian trunk neural crest polarity for directional delamination and migration. Nat Commun. 2017;8:1185 pubmed publisher
|
Gonsberg A, Jung S, Ulbrich S, Origi A, Ziska A, Baier M, et al. The Sec61/SecY complex is inherently deficient in translocating intrinsically disordered proteins. J Biol Chem. 2017;292:21383-21396 pubmed publisher
|
Zhang L, Rajbhandari P, Priest C, Sandhu J, Wu X, TEMEL R, et al. Inhibition of cholesterol biosynthesis through RNF145-dependent ubiquitination of SCAP. elife. 2017;6: pubmed publisher
|
Liu Y, Mattila J, Ventelä S, Yadav L, Zhang W, Lamichane N, et al. PWP1 Mediates Nutrient-Dependent Growth Control through Nucleolar Regulation of Ribosomal Gene Expression. Dev Cell. 2017;43:240-252.e5 pubmed publisher
|
Thirunavukkarasan M, Wang C, Rao A, Hind T, Teo Y, Siddiquee A, et al. Short-chain fatty acid receptors inhibit invasive phenotypes in breast cancer cells. PLoS ONE. 2017;12:e0186334 pubmed publisher
|
Kim A, Choi E, Kim M, Choi K. Angiotensin-converting enzyme Ance is cooperatively regulated by Mad and Pannier in Drosophila imaginal discs. Sci Rep. 2017;7:13174 pubmed publisher
|
Singh P, Roukounakis A, Frank D, Kirschnek S, Das K, Neumann S, et al. Dynein light chain 1 induces assembly of large Bim complexes on mitochondria that stabilize Mcl-1 and regulate apoptosis. Genes Dev. 2017;31:1754-1769 pubmed publisher
|
Lear T, Dunn S, McKelvey A, Mir A, Evankovich J, Chen B, et al. RING finger protein 113A regulates C-X-C chemokine receptor type 4 stability and signaling. Am J Physiol Cell Physiol. 2017;313:C584-C592 pubmed publisher
|
Chua N, Howe V, Jatana N, Thukral L, Brown A. A conserved degron containing an amphipathic helix regulates the cholesterol-mediated turnover of human squalene monooxygenase, a rate-limiting enzyme in cholesterol synthesis. J Biol Chem. 2017;292:19959-19973 pubmed publisher
|
Chen Y, Khoo S, Leach R, Wang K. MTA3 Regulates Extravillous Trophoblast Invasion Through NuRD Complex. AIMS Med Sci. 2017;4:17-27 pubmed publisher
|
Sepp M, Vihma H, Nurm K, Urb M, Page S, Roots K, et al. The Intellectual Disability and Schizophrenia Associated Transcription Factor TCF4 Is Regulated by Neuronal Activity and Protein Kinase A. J Neurosci. 2017;37:10516-10527 pubmed publisher
|
Kim H, Raffler J, Lu W, Lee J, Abbey D, Saleheen D, et al. Fine Mapping and Functional Analysis Reveal a Role of SLC22A1 in Acylcarnitine Transport. Am J Hum Genet. 2017;101:489-502 pubmed publisher
|
Ha Kim K, Sadikot R, Yeon Lee J, Jeong H, Oh Y, Blackwell T, et al. Suppressed ubiquitination of Nrf2 by p47phox contributes to Nrf2 activation. Free Radic Biol Med. 2017;113:48-58 pubmed publisher
|
Yim C, Bikorimana E, Khan E, Warzecha J, Shin L, Rodriguez J, et al. G0S2 represses PI3K/mTOR signaling and increases sensitivity to PI3K/mTOR pathway inhibitors in breast cancer. Cell Cycle. 2017;16:2146-2155 pubmed publisher
|
Merrill N, Schipper J, Karnes J, Kauffman A, Martin K, Mackeigan J. PI3K-C2? knockdown decreases autophagy and maturation of endocytic vesicles. PLoS ONE. 2017;12:e0184909 pubmed publisher
|
Weir N, Kamber R, Martenson J, Denic V. The AAA protein Msp1 mediates clearance of excess tail-anchored proteins from the peroxisomal membrane. elife. 2017;6: pubmed publisher
|
Chen J, Tresenrider A, Chia M, McSwiggen D, Spedale G, Jorgensen V, et al. Kinetochore inactivation by expression of a repressive mRNA. elife. 2017;6: pubmed publisher
|
Bartolomé A, García Aguilar A, Asahara S, Kido Y, Guillen C, Pajvani U, et al. MTORC1 Regulates both General Autophagy and Mitophagy Induction after Oxidative Phosphorylation Uncoupling. Mol Cell Biol. 2017;37: pubmed publisher
|
Goodman L, Zallocchi M. Integrin α8 and Pcdh15 act as a complex to regulate cilia biogenesis in sensory cells. J Cell Sci. 2017;130:3698-3712 pubmed publisher
|
Cole C, Russler Germain D, Ketkar S, Verdoni A, Smith A, Bangert C, et al. Haploinsufficiency for DNA methyltransferase 3A predisposes hematopoietic cells to myeloid malignancies. J Clin Invest. 2017;127:3657-3674 pubmed publisher
|
Xu Q, Jitkaew S, Choksi S, Kadigamuwa C, Qu J, Choe M, et al. The cytoplasmic nuclear receptor RAR? controls RIP1 initiated cell death when cIAP activity is inhibited. Nat Commun. 2017;8:425 pubmed publisher
|
Read K, Powell M, Baker C, Sreekumar B, Ringel Scaia V, Bachus H, et al. Integrated STAT3 and Ikaros Zinc Finger Transcription Factor Activities Regulate Bcl-6 Expression in CD4+ Th Cells. J Immunol. 2017;199:2377-2387 pubmed publisher
|
Sleigh J, Gómez Martín A, Wei N, Bai G, Yang X, Schiavo G. Neuropilin 1 sequestration by neuropathogenic mutant glycyl-tRNA synthetase is permissive to vascular homeostasis. Sci Rep. 2017;7:9216 pubmed publisher
|
Romero Pozuelo J, Demetriades C, Schroeder P, Teleman A. CycD/Cdk4 and Discontinuities in Dpp Signaling Activate TORC1 in the Drosophila Wing Disc. Dev Cell. 2017;42:376-387.e5 pubmed publisher
|
Holler C, Taylor G, Deng Q, Kukar T. Intracellular Proteolysis of Progranulin Generates Stable, Lysosomal Granulins that Are Haploinsufficient in Patients with Frontotemporal Dementia Caused by GRN Mutations. Eneuro. 2017;4: pubmed publisher
|
Fu L, Liu K, Sun M, Tian C, Sun R, Morales Betanzos C, et al. Systematic and Quantitative Assessment of Hydrogen Peroxide Reactivity With Cysteines Across Human Proteomes. Mol Cell Proteomics. 2017;16:1815-1828 pubmed publisher
|
Mezzadra R, Sun C, Jae L, Gomez Eerland R, de Vries E, Wu W, et al. Identification of CMTM6 and CMTM4 as PD-L1 protein regulators. Nature. 2017;549:106-110 pubmed publisher
|
Hiraike Y, Waki H, Yu J, Nakamura M, Miyake K, Nagano G, et al. NFIA co-localizes with PPARγ and transcriptionally controls the brown fat gene program. Nat Cell Biol. 2017;19:1081-1092 pubmed publisher
|
Thomas A, Sulli C, Davidson E, Berdougo E, Phillips M, Puffer B, et al. The Bitter Taste Receptor TAS2R16 Achieves High Specificity and Accommodates Diverse Glycoside Ligands by using a Two-faced Binding Pocket. Sci Rep. 2017;7:7753 pubmed publisher
|
Stoyle C, Stephens P, Humphreys D, Heywood S, Cain K, Bulleid N. IgG light chain-independent secretion of heavy chain dimers: consequence for therapeutic antibody production and design. Biochem J. 2017;474:3179-3188 pubmed publisher
|
Yao Z, Yaeger R, Rodrik Outmezguine V, Tao A, Torres N, Chang M, et al. Tumours with class 3 BRAF mutants are sensitive to the inhibition of activated RAS. Nature. 2017;548:234-238 pubmed publisher
|
Kim K, Boo K, Yu Y, Oh S, Kim H, Jeon Y, et al. ROR? controls hepatic lipid homeostasis via negative regulation of PPAR? transcriptional network. Nat Commun. 2017;8:162 pubmed publisher
|
Romagnuolo R, Scipione C, Marcovina S, Gemin M, Seidah N, Boffa M, et al. Roles of the low density lipoprotein receptor and related receptors in inhibition of lipoprotein(a) internalization by proprotein convertase subtilisin/kexin type 9. PLoS ONE. 2017;12:e0180869 pubmed publisher
|
French B, Westhorpe F, Limouse C, Straight A. Xenopus laevis M18BP1 Directly Binds Existing CENP-A Nucleosomes to Promote Centromeric Chromatin Assembly. Dev Cell. 2017;42:190-199.e10 pubmed publisher
|
Lin D, Cherepanova N, Bozzacco L, Macdonald M, Gilmore R, Tai A. Dengue Virus Hijacks a Noncanonical Oxidoreductase Function of a Cellular Oligosaccharyltransferase Complex. MBio. 2017;8: pubmed publisher
|
Zufferey R, Pirani K, Cheung See Kit M, Lee S, Williams T, Chen D, et al. The Trypanosoma brucei dihydroxyacetonephosphate acyltransferase TbDAT is dispensable for normal growth but important for synthesis of ether glycerophospholipids. PLoS ONE. 2017;12:e0181432 pubmed publisher
|
Xue Y, Martelotto L, Baslan T, Vides A, SOLOMON M, Mai T, et al. An approach to suppress the evolution of resistance in BRAFV600E-mutant cancer. Nat Med. 2017;23:929-937 pubmed publisher
|
Hansen J, Lotta L, Eberhardt A, Schor N, Li X. EYA1 expression and subcellular localization in neuroblastoma and its association with prognostic markers. J Cancer Res Ther (Manch). 2016;4:11-18 pubmed publisher
|
Murray A, Varela F, Hyland T, Schoenbeck A, White J, Tanabe L, et al. Phosphorylation of the type II transmembrane serine protease, TMPRSS13, in hepatocyte growth factor activator inhibitor-1 and -2-mediated cell-surface localization. J Biol Chem. 2017;292:14867-14884 pubmed publisher
|
Raab M, Lu Y, Köhler K, Smith X, Strebhardt K, Rudd C. LFA-1 activates focal adhesion kinases FAK1/PYK2 to generate LAT-GRB2-SKAP1 complexes that terminate T-cell conjugate formation. Nat Commun. 2017;8:16001 pubmed publisher
|
Batinovic S, McHugh E, Chisholm S, Matthews K, Liu B, Dumont L, et al. An exported protein-interacting complex involved in the trafficking of virulence determinants in Plasmodium-infected erythrocytes. Nat Commun. 2017;8:16044 pubmed publisher
|
Hautbergue G, Castelli L, Ferraiuolo L, Sanchez Martinez A, Cooper Knock J, Higginbottom A, et al. SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits. Nat Commun. 2017;8:16063 pubmed publisher
|
Paclíková P, Bernatik O, Radaszkiewicz T, Bryja V. The N-Terminal Part of the Dishevelled DEP Domain Is Required for Wnt/β-Catenin Signaling in Mammalian Cells. Mol Cell Biol. 2017;37: pubmed publisher
|
Giese A, Tang Y, Sinha G, Bowl M, Goldring A, Parker A, et al. CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells. Nat Commun. 2017;8:43 pubmed publisher
|
Cabukusta B, Nettebrock N, Kol M, Hilderink A, Tafesse F, Holthuis J. Ceramide phosphoethanolamine synthase SMSr is a target of caspase-6 during apoptotic cell death. Biosci Rep. 2017;37: pubmed publisher
|
Izuogu A, McNally K, Harris S, Youseff B, Presloid J, Burlak C, et al. Interferon signaling in Peromyscus leucopus confers a potent and specific restriction to vector-borne flaviviruses. PLoS ONE. 2017;12:e0179781 pubmed publisher
|
Nakamura F, Okada T, Shishikura M, Uetani N, Taniguchi M, Yagi T, et al. Protein Tyrosine Phosphatase δ Mediates the Sema3A-Induced Cortical Basal Dendritic Arborization through the Activation of Fyn Tyrosine Kinase. J Neurosci. 2017;37:7125-7139 pubmed publisher
|
Li P, Jin H, Koch B, Abblett R, Han X, Yates J, et al. Cleavage of the SUN-domain protein Mps3 at its N-terminus regulates centrosome disjunction in budding yeast meiosis. PLoS Genet. 2017;13:e1006830 pubmed publisher
|
Brown K, Filuta A, Ludwig M, Seuwen K, Jaros J, Vidal S, et al. Epithelial Gpr116 regulates pulmonary alveolar homeostasis via Gq/11 signaling. JCI Insight. 2017;2: pubmed publisher
|
Ngo K, Andrade I, Hartenstein V. Spatio-temporal pattern of neuronal differentiation in the Drosophila visual system: A user's guide to the dynamic morphology of the developing optic lobe. Dev Biol. 2017;428:1-24 pubmed publisher
|
Mendoza E, Scharff C. Protein-Protein Interaction Among the FoxP Family Members and their Regulation of Two Target Genes, VLDLR and CNTNAP2 in the Zebra Finch Song System. Front Mol Neurosci. 2017;10:112 pubmed publisher
|
Kang H, Oka S, Lee D, Park J, Aponte A, Jung Y, et al. Sirt1 carboxyl-domain is an ATP-repressible domain that is transferrable to other proteins. Nat Commun. 2017;8:15560 pubmed publisher
|
Saha M, Mitsuhashi S, Jones M, Manko K, Reddy H, Bruels C, et al. Consequences of MEGF10 deficiency on myoblast function and Notch1 interactions. Hum Mol Genet. 2017;26:2984-3000 pubmed publisher
|
Xu Y, Greenberg R, Schonbrunn E, Wang P. Meiosis-specific proteins MEIOB and SPATA22 cooperatively associate with the single-stranded DNA-binding replication protein A complex and DNA double-strand breaks. Biol Reprod. 2017;96:1096-1104 pubmed publisher
|
Ehrhardt N, Doche M, Chen S, Mao H, Walsh M, Bedoya C, et al. Hepatic Tm6sf2 overexpression affects cellular ApoB-trafficking, plasma lipid levels, hepatic steatosis and atherosclerosis. Hum Mol Genet. 2017;26:2719-2731 pubmed publisher
|
Hung V, Lam S, Udeshi N, Svinkina T, Guzman G, Mootha V, et al. Proteomic mapping of cytosol-facing outer mitochondrial and ER membranes in living human cells by proximity biotinylation. elife. 2017;6: pubmed publisher
|
Ando M, Fiesel F, Hudec R, Caulfield T, Ogaki K, Górka Skoczylas P, et al. The PINK1 p.I368N mutation affects protein stability and ubiquitin kinase activity. Mol Neurodegener. 2017;12:32 pubmed publisher
|
Orr A, Rutaganira F, de Roulet D, Huang E, Hertz N, Shokat K, et al. Long-term oral kinetin does not protect against ?-synuclein-induced neurodegeneration in rodent models of Parkinson's disease. Neurochem Int. 2017;109:106-116 pubmed publisher
|
Cui J, Zhu Q, Zhang H, Cianfrocco M, Leschziner A, Dixon J, et al. Structure of Fam20A reveals a pseudokinase featuring a unique disulfide pattern and inverted ATP-binding. elife. 2017;6: pubmed publisher
|
Mesrouze Y, Bokhovchuk F, Meyerhofer M, Fontana P, Zimmermann C, Martin T, et al. Dissection of the interaction between the intrinsically disordered YAP protein and the transcription factor TEAD. elife. 2017;6: pubmed publisher
|
Sullivan K, Rojas K, Cerione R, Nakano I, Wilson K. The stem cell/cancer stem cell marker ALDH1A3 regulates the expression of the survival factor tissue transglutaminase, in mesenchymal glioma stem cells. Oncotarget. 2017;8:22325-22343 pubmed publisher
|
Zykova T, Zhu F, Wang L, Li H, Bai R, Lim D, et al. The T-LAK Cell-originated Protein Kinase Signal Pathway Promotes Colorectal Cancer Metastasis. EBioMedicine. 2017;18:73-82 pubmed publisher
|
Zhou C, Li C, Zhou B, Sun H, Koullourou V, Holt I, et al. Novel nesprin-1 mutations associated with dilated cardiomyopathy cause nuclear envelope disruption and defects in myogenesis. Hum Mol Genet. 2017;26:2258-2276 pubmed publisher
|
Lee J, Yoo E, Lee H, Park K, Hur J, Lim C. LSM12 and ME31B/DDX6 Define Distinct Modes of Posttranscriptional Regulation by ATAXIN-2 Protein Complex in Drosophila Circadian Pacemaker Neurons. Mol Cell. 2017;66:129-140.e7 pubmed publisher
|
Pan B, Wang X, Nishioka C, Honda G, Yokoyama A, Zeng L, et al. G-protein coupled receptor 15 mediates angiogenesis and cytoprotective function of thrombomodulin. Sci Rep. 2017;7:692 pubmed publisher
|
Timblin G, Xie L, Tjian R, Schlissel M. Dual Mechanism of Rag Gene Repression by c-Myb during Pre-B Cell Proliferation. Mol Cell Biol. 2017;37: pubmed publisher
|
Földi I, Anthoney N, Harrison N, Gangloff M, Verstak B, Nallasivan M, et al. Three-tier regulation of cell number plasticity by neurotrophins and Tolls in Drosophila. J Cell Biol. 2017;216:1421-1438 pubmed publisher
|
Wu C, Wang Y, Choe K. F-Box Protein XREP-4 Is a New Regulator of the Oxidative Stress Response in Caenorhabditis elegans. Genetics. 2017;206:859-871 pubmed publisher
|
Luganini A, Cavaletto N, Raimondo S, Geuna S, Gribaudo G. Loss of the Human Cytomegalovirus US16 Protein Abrogates Virus Entry into Endothelial and Epithelial Cells by Reducing the Virion Content of the Pentamer. J Virol. 2017;91: pubmed publisher
|
Yadav L, Tamene F, Göös H, van Drogen A, Katainen R, Aebersold R, et al. Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics. Cell Syst. 2017;4:430-444.e5 pubmed publisher
|
Sarper M, Allen M, Gomm J, Haywood L, Decock J, Thirkettle S, et al. Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function. Breast Cancer Res. 2017;19:33 pubmed publisher
|
Alok A, Lei Z, Jagannathan N, Kaur S, Harmston N, Rozen S, et al. Wnt proteins synergize to activate ?-catenin signaling. J Cell Sci. 2017;130:1532-1544 pubmed publisher
|
Iwahori S, Umaña A, VanDeusen H, Kalejta R. Human cytomegalovirus-encoded viral cyclin-dependent kinase (v-CDK) UL97 phosphorylates and inactivates the retinoblastoma protein-related p107 and p130 proteins. J Biol Chem. 2017;292:6583-6599 pubmed publisher
|
Satake T, Yamashita K, Hayashi K, Miyatake S, Tamura Nakano M, Doi H, et al. MTCL1 plays an essential role in maintaining Purkinje neuron axon initial segment. EMBO J. 2017;36:1227-1242 pubmed publisher
|
Koole C, Reynolds C, Mobarec J, Hick C, Sexton P, Sakmar T. Genetically encoded photocross-linkers determine the biological binding site of exendin-4 peptide in the N-terminal domain of the intact human glucagon-like peptide-1 receptor (GLP-1R). J Biol Chem. 2017;292:7131-7144 pubmed publisher
|
Snyder J, Rochelle L, Ray C, Pack T, Bock C, Lubkov V, et al. Inhibiting clathrin-mediated endocytosis of the leucine-rich G protein-coupled receptor-5 diminishes cell fitness. J Biol Chem. 2017;292:7208-7222 pubmed publisher
|
Wang J, Rajbhandari P, Damianov A, Han A, Sallam T, Waki H, et al. RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs. J Clin Invest. 2017;127:987-1004 pubmed publisher
|
Morelli F, Mediani L, Heldens L, Bertacchini J, Bigi I, Carrà A, et al. An interaction study in mammalian cells demonstrates weak binding of HSPB2 to BAG3, which is regulated by HSPB3 and abrogated by HSPB8. Cell Stress Chaperones. 2017;22:531-540 pubmed publisher
|
Geier A, Macias R, Bettinger D, Weiss J, Bantel H, Jahn D, et al. The lack of the organic cation transporter OCT1 at the plasma membrane of tumor cells precludes a positive response to sorafenib in patients with hepatocellular carcinoma. Oncotarget. 2017;8:15846-15857 pubmed publisher
|
Pan B, Wang X, Kojima S, Nishioka C, Yokoyama A, Honda G, et al. The Fifth Epidermal Growth Factor-like Region of Thrombomodulin Alleviates Murine Graft-versus-Host Disease in a G-Protein Coupled Receptor 15 Dependent Manner. Biol Blood Marrow Transplant. 2017;23:746-756 pubmed publisher
|
Nounamo B, Li Y, O Byrne P, Kearney A, Khan A, Liu J. An interaction domain in human SAMD9 is essential for myxoma virus host-range determinant M062 antagonism of host anti-viral function. Virology. 2017;503:94-102 pubmed publisher
|
Mukherjee A, Wang Z, Kinlough C, Poland P, Marciszyn A, Montalbetti N, et al. Specific Palmitoyltransferases Associate with and Activate the Epithelial Sodium Channel. J Biol Chem. 2017;292:4152-4163 pubmed publisher
|
Sterky F, Trotter J, Lee S, Recktenwald C, Du X, Zhou B, et al. Carbonic anhydrase-related protein CA10 is an evolutionarily conserved pan-neurexin ligand. Proc Natl Acad Sci U S A. 2017;114:E1253-E1262 pubmed publisher
|
Cabukusta B, Kol M, Kneller L, Hilderink A, Bickert A, Mina J, et al. ER residency of the ceramide phosphoethanolamine synthase SMSr relies on homotypic oligomerization mediated by its SAM domain. Sci Rep. 2017;7:41290 pubmed publisher
|
Lennemann N, Coyne C. Dengue and Zika viruses subvert reticulophagy by NS2B3-mediated cleavage of FAM134B. Autophagy. 2017;13:322-332 pubmed publisher
|
Jelinic P, Eccles L, Tseng J, Cybulska P, Wielgos M, Powell S, et al. The EMSY threonine 207 phospho-site is required for EMSYdriven suppression of DNA damage repair. Oncotarget. 2017;8:13792-13804 pubmed publisher
|
van den Berg D, Azzarelli R, Oishi K, Martynoga B, Urbán N, Dekkers D, et al. Nipbl Interacts with Zfp609 and the Integrator Complex to Regulate Cortical Neuron Migration. Neuron. 2017;93:348-361 pubmed publisher
|
Kozlova N, Wottawa M, Katschinski D, Kristiansen G, Kietzmann T. Hypoxia-inducible factor prolyl hydroxylase 2 (PHD2) is a direct regulator of epidermal growth factor receptor (EGFR) signaling in breast cancer. Oncotarget. 2017;8:9885-9898 pubmed publisher
|
Girouard M, Pool M, Alchini R, Rambaldi I, Fournier A. RhoA Proteolysis Regulates the Actin Cytoskeleton in Response to Oxidative Stress. PLoS ONE. 2016;11:e0168641 pubmed publisher
|
Urbanus M, Quaile A, Stogios P, Morar M, Rao C, Di Leo R, et al. Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila. Mol Syst Biol. 2016;12:893 pubmed publisher
|
Kadoch C, Williams R, Calarco J, Miller E, Weber C, Braun S, et al. Dynamics of BAF-Polycomb complex opposition on heterochromatin in normal and oncogenic states. Nat Genet. 2017;49:213-222 pubmed publisher
|
Velasco S, Ibrahim M, Kakumanu A, Garipler G, Aydin B, Al Sayegh M, et al. A Multi-step Transcriptional and Chromatin State Cascade Underlies Motor Neuron Programming from Embryonic Stem Cells. Cell Stem Cell. 2017;20:205-217.e8 pubmed publisher
|
Homma S, Beermann M, Yu B, BOYCE F, Miller J. Nuclear bodies reorganize during myogenesis in vitro and are differentially disrupted by expression of FSHD-associated DUX4. Skelet Muscle. 2016;6:42 pubmed
|
Singh R, Dhanyamraju P, Lauth M. DYRK1B blocks canonical and promotes non-canonical Hedgehog signaling through activation of the mTOR/AKT pathway. Oncotarget. 2017;8:833-845 pubmed publisher
|
Singh R, Dagnino L. CDH1 regulates E2F1 degradation in response to differentiation signals in keratinocytes. Oncotarget. 2017;8:4977-4993 pubmed publisher
|
Jaitner C, Reddy C, Abentung A, Whittle N, Rieder D, Delekate A, et al. Satb2 determines miRNA expression and long-term memory in the adult central nervous system. elife. 2016;5: pubmed publisher
|
Burg L, Zhang K, Bonawitz T, Grajevskaja V, Bellipanni G, Waring R, et al. Internal epitope tagging informed by relative lack of sequence conservation. Sci Rep. 2016;6:36986 pubmed publisher
|
Ü Basmanav F, Cau L, Tafazzoli A, Méchin M, Wolf S, Romano M, et al. Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome. Am J Hum Genet. 2016;99:1292-1304 pubmed publisher
|
Kostrzak A, Caval V, Escande M, Pliquet E, Thalmensi J, Bestetti T, et al. APOBEC3A intratumoral DNA electroporation in mice. Gene Ther. 2017;24:74-83 pubmed publisher
|
Magallón Tejada A, Machevo S, Cisteró P, Lavstsen T, Aide P, Rubio M, et al. Cytoadhesion to gC1qR through Plasmodium falciparum Erythrocyte Membrane Protein 1 in Severe Malaria. PLoS Pathog. 2016;12:e1006011 pubmed publisher
|
Zimmer A, Koshland D. Differential roles of the RNases H in preventing chromosome instability. Proc Natl Acad Sci U S A. 2016;113:12220-12225 pubmed
|
Wu C, Deonarine A, Przybysz A, Strange K, Choe K. The Skp1 Homologs SKR-1/2 Are Required for the Caenorhabditis elegans SKN-1 Antioxidant/Detoxification Response Independently of p38 MAPK. PLoS Genet. 2016;12:e1006361 pubmed publisher
|
Balenga N, Azimzadeh P, Hogue J, Staats P, Shi Y, Koh J, et al. Orphan Adhesion GPCR GPR64/ADGRG2 Is Overexpressed in Parathyroid Tumors and Attenuates Calcium-Sensing Receptor-Mediated Signaling. J Bone Miner Res. 2017;32:654-666 pubmed publisher
|
Ly K, Essalmani R, Desjardins R, Seidah N, Day R. An Unbiased Mass Spectrometry Approach Identifies Glypican-3 as an Interactor of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) and Low Density Lipoprotein Receptor (LDLR) in Hepatocellular Carcinoma Cells. J Biol Chem. 2016;291:24676-24687 pubmed
|
Głąb B, Beganovic M, Anaokar S, Hao M, Rasmusson A, Patton Vogt J, et al. Cloning of Glycerophosphocholine Acyltransferase (GPCAT) from Fungi and Plants: A NOVEL ENZYME IN PHOSPHATIDYLCHOLINE SYNTHESIS. J Biol Chem. 2016;291:25066-25076 pubmed
|
Hinds T, Burns K, Hosick P, McBeth L, Nestor Kalinoski A, Drummond H, et al. Biliverdin Reductase A Attenuates Hepatic Steatosis by Inhibition of Glycogen Synthase Kinase (GSK) 3? Phosphorylation of Serine 73 of Peroxisome Proliferator-activated Receptor (PPAR) ?. J Biol Chem. 2016;291:25179-25191 pubmed
|
Rowley P, Ho B, Bushong S, Johnson A, Sawyer S. XRN1 Is a Species-Specific Virus Restriction Factor in Yeasts. PLoS Pathog. 2016;12:e1005890 pubmed publisher
|
Zhang D, Bergsneider M, Wang M, Heaney A. Targeting the ERK pathway for the treatment of Cushing's disease. Oncotarget. 2016;7:69149-69158 pubmed publisher
|
Arvind T, Rangarajan P. Mouse Apolipoprotein L9 is a phosphatidylethanolamine-binding protein. Biochem Biophys Res Commun. 2016;479:636-642 pubmed publisher
|
Broix L, Jagline H, Ivanova E, Schmucker S, Drouot N, Clayton Smith J, et al. Mutations in the HECT domain of NEDD4L lead to AKT-mTOR pathway deregulation and cause periventricular nodular heterotopia. Nat Genet. 2016;48:1349-1358 pubmed publisher
|
Pashkova N, Peterson T, Krishnamani V, Breheny P, Stamnes M, Piper R. DEEPN as an Approach for Batch Processing of Yeast 2-Hybrid Interactions. Cell Rep. 2016;17:303-315 pubmed publisher
|
Miyake N, Fukai R, Ohba C, Chihara T, Miura M, Shimizu H, et al. Biallelic TBCD Mutations Cause Early-Onset Neurodegenerative Encephalopathy. Am J Hum Genet. 2016;99:950-961 pubmed publisher
|
Mobin M, Gerstberger S, Teupser D, Campana B, Charisse K, Heim M, et al. The RNA-binding protein vigilin regulates VLDL secretion through modulation of Apob mRNA translation. Nat Commun. 2016;7:12848 pubmed publisher
|
Edwards A, Meijer D, Guerra R, Molenaar R, Alberta J, Bernal F, et al. Challenges in Targeting a Basic Helix-Loop-Helix Transcription Factor with Hydrocarbon-Stapled Peptides. ACS Chem Biol. 2016;11:3146-3153 pubmed
|
Hashimoto A, Hashimoto S, Sugino H, Yoshikawa A, Onodera Y, Handa H, et al. ZEB1 induces EPB41L5 in the cancer mesenchymal program that drives ARF6-based invasion, metastasis and drug resistance. Oncogenesis. 2016;5:e259 pubmed publisher
|
Ouyang Q, Nakayama T, Baytas O, Davidson S, Yang C, Schmidt M, et al. Mutations in mitochondrial enzyme GPT2 cause metabolic dysfunction and neurological disease with developmental and progressive features. Proc Natl Acad Sci U S A. 2016;113:E5598-607 pubmed publisher
|
Mitchell A, Javidfar B, Bicks L, Neve R, Garbett K, Lander S, et al. Longitudinal assessment of neuronal 3D genomes in mouse prefrontal cortex. Nat Commun. 2016;7:12743 pubmed publisher
|
Eberhardt A, Hansen J, Koster J, Lotta L, Wang S, Livingstone E, et al. Protein arginine methyltransferase 1 is a novel regulator of MYCN in neuroblastoma. Oncotarget. 2016;7:63629-63639 pubmed publisher
|
Loh K, Stawski P, Draycott A, Udeshi N, Lehrman E, Wilton D, et al. Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts. Cell. 2016;166:1295-1307.e21 pubmed publisher
|
Duffy S, Fam H, Wang Y, Styles E, Kim J, Ang J, et al. Overexpression screens identify conserved dosage chromosome instability genes in yeast and human cancer. Proc Natl Acad Sci U S A. 2016;113:9967-76 pubmed publisher
|
Hegarty J, Krzeminski J, Sharma A, Guzman Villanueva D, Weissig V, Stewart D. Bolaamphiphile-based nanocomplex delivery of phosphorothioate gapmer antisense oligonucleotides as a treatment for Clostridium difficile. Int J Nanomedicine. 2016;11:3607-19 pubmed publisher
|
Kolar M, Kamat S, Parsons W, Homan E, Maher T, Peroni O, et al. Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase. Biochemistry. 2016;55:4636-41 pubmed publisher
|
Filatova A, Seidel S, Bogurcu N, Graf S, Garvalov B, Acker T. Acidosis Acts through HSP90 in a PHD/VHL-Independent Manner to Promote HIF Function and Stem Cell Maintenance in Glioma. Cancer Res. 2016;76:5845-5856 pubmed
|
Bürgi J, Xue B, Uversky V, van der Goot F. Intrinsic Disorder in Transmembrane Proteins: Roles in Signaling and Topology Prediction. PLoS ONE. 2016;11:e0158594 pubmed publisher
|
Rautengarten C, Ebert B, Liu L, Stonebloom S, Smith Moritz A, Pauly M, et al. The Arabidopsis Golgi-localized GDP-L-fucose transporter is required for plant development. Nat Commun. 2016;7:12119 pubmed publisher
|
Bonner J, Choi K, Xue X, Torres N, Szakal B, Wei L, et al. Smc5/6 Mediated Sumoylation of the Sgs1-Top3-Rmi1 Complex Promotes Removal of Recombination Intermediates. Cell Rep. 2016;16:368-378 pubmed publisher
|
Chen K, Lin G, Haelterman N, Ho T, Li T, Li Z, et al. Loss of Frataxin induces iron toxicity, sphingolipid synthesis, and Pdk1/Mef2 activation, leading to neurodegeneration. elife. 2016;5: pubmed publisher
|
Ortiz D, Glassbrook J, Pellett P. Protein-Protein Interactions Suggest Novel Activities of Human Cytomegalovirus Tegument Protein pUL103. J Virol. 2016;90:7798-810 pubmed publisher
|
Dick M, Sborgi L, Rühl S, Hiller S, Broz P. ASC filament formation serves as a signal amplification mechanism for inflammasomes. Nat Commun. 2016;7:11929 pubmed publisher
|
Kathania M, Khare P, Zeng M, Cantarel B, Zhang H, Ueno H, et al. Itch inhibits IL-17-mediated colon inflammation and tumorigenesis by ROR-?t ubiquitination. Nat Immunol. 2016;17:997-1004 pubmed publisher
|
Gómez Sánchez R, Yakhine Diop S, Bravo San Pedro J, Pizarro Estrella E, Rodríguez Arribas M, Climent V, et al. PINK1 deficiency enhances autophagy and mitophagy induction. Mol Cell Oncol. 2016;3:e1046579 pubmed publisher
|
Faber E, Gripp E, Maurischat S, Kaspers B, Tedin K, Menz S, et al. Novel Immunomodulatory Flagellin-Like Protein FlaC in Campylobacter jejuni and Other Campylobacterales. mSphere. 2016;1: pubmed publisher
|
Bendris N, Stearns C, Reis C, Rodriguez Canales J, Liu H, Witkiewicz A, et al. Sorting nexin 9 negatively regulates invadopodia formation and function in cancer cells. J Cell Sci. 2016;129:2804-16 pubmed publisher
|
Backhaus P, Langenhan T, Neuser K. Effects of transgenic expression of botulinum toxins in Drosophila. J Neurogenet. 2016;30:22-31 pubmed publisher
|
Palmer E, Jarrett K, Sachdev R, Al Zahrani F, Hashem M, Ibrahim N, et al. Neuronal deficiency of ARV1 causes an autosomal recessive epileptic encephalopathy. Hum Mol Genet. 2016;25:3042-3054 pubmed
|
Bahia P, Parks T, Stanford K, Mitchell D, Varma S, Stevens S, et al. The exceptionally high reactivity of Cys 621 is critical for electrophilic activation of the sensory nerve ion channel TRPA1. J Gen Physiol. 2016;147:451-65 pubmed publisher
|
Wang T, Xu W, Qin M, Yang Y, Bao P, Shen F, et al. Pathogenic Mutations in the Valosin-containing Protein/p97(VCP) N-domain Inhibit the SUMOylation of VCP and Lead to Impaired Stress Response. J Biol Chem. 2016;291:14373-84 pubmed publisher
|
Marzahn M, Marada S, Lee J, Nourse A, Kenrick S, Zhao H, et al. Higher-order oligomerization promotes localization of SPOP to liquid nuclear speckles. EMBO J. 2016;35:1254-75 pubmed publisher
|
Sun Y, Hu W, Yu X, Liu Z, Tarran R, Ravid K, et al. Actinin-1 binds to the C-terminus of A2B adenosine receptor (A2BAR) and enhances A2BAR cell-surface expression. Biochem J. 2016;473:2179-86 pubmed publisher
|
Ni T, Kuperwasser C. Premature polyadenylation of MAGI3 produces a dominantly-acting oncogene in human breast cancer. elife. 2016;5: pubmed publisher
|
Speer S, Li Z, Buta S, Payelle Brogard B, Qian L, Vigant F, et al. ISG15 deficiency and increased viral resistance in humans but not mice. Nat Commun. 2016;7:11496 pubmed publisher
|
Link S, Grund S, Diederichs S. Alternative splicing affects the subcellular localization of Drosha. Nucleic Acids Res. 2016;44:5330-43 pubmed publisher
|
Lee S, Kang M, Park J, Lee G, Ting A, Rhee H. APEX Fingerprinting Reveals the Subcellular Localization of Proteins of Interest. Cell Rep. 2016;15:1837-47 pubmed publisher
|
Chen S, Lee B, Lee A, Modzelewski A, He L. Highly Efficient Mouse Genome Editing by CRISPR Ribonucleoprotein Electroporation of Zygotes. J Biol Chem. 2016;291:14457-67 pubmed publisher
|
Messina G, Atterrato M, Fanti L, Giordano E, Dimitri P. Expression of human Cfdp1 gene in Drosophila reveals new insights into the function of the evolutionarily conserved BCNT protein family. Sci Rep. 2016;6:25511 pubmed publisher
|
Fryland T, Christensen J, Pallesen J, Mattheisen M, Palmfeldt J, Bak M, et al. Identification of the BRD1 interaction network and its impact on mental disorder risk. Genome Med. 2016;8:53 pubmed publisher
|
Peng Q, Wang Y, Li M, Yuan D, Xu M, Li C, et al. cGMP-Dependent Protein Kinase Encoded by foraging Regulates Motor Axon Guidance in Drosophila by Suppressing Lola Function. J Neurosci. 2016;36:4635-46 pubmed publisher
|
Saunier C, Støve S, Popp B, Gerard B, Blenski M, AhMew N, et al. Expanding the Phenotype Associated with NAA10-Related N-Terminal Acetylation Deficiency. Hum Mutat. 2016;37:755-64 pubmed publisher
|
Blas Rus N, Bustos Morán E, Perez de Castro I, de Carcer G, Borroto A, Camafeita E, et al. Aurora A drives early signalling and vesicle dynamics during T-cell activation. Nat Commun. 2016;7:11389 pubmed publisher
|
Kumar A, Chalamalasetty R, Kennedy M, Thomas S, Inala S, Garriock R, et al. Zfp703 Is a Wnt/?-Catenin Feedback Suppressor Targeting the ?-Catenin/Tcf1 Complex. Mol Cell Biol. 2016;36:1793-802 pubmed publisher
|
Kurkinen K, Marttinen M, Turner L, Natunen T, Mäkinen P, Haapalinna F, et al. SEPT8 modulates ?-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1. J Cell Sci. 2016;129:2224-38 pubmed publisher
|
Nagashima H, Okuyama Y, Hayashi T, Ishii N, So T. TNFR-Associated Factors 2 and 5 Differentially Regulate the Instructive IL-6 Receptor Signaling Required for Th17 Development. J Immunol. 2016;196:4082-9 pubmed publisher
|
Kuzuya A, Zoltowska K, Post K, Arimon M, Li X, Svirsky S, et al. Identification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid beta. BMC Biol. 2016;14:25 pubmed publisher
|
Cheng H, Bao X, Rao H. The F-box Protein Rcy1 Is Involved in the Degradation of Histone H3 Variant Cse4 and Genome Maintenance. J Biol Chem. 2016;291:10372-7 pubmed publisher
|
Hasegawa K, Yasuda T, Shiraishi C, Fujiwara K, Przedborski S, Mochizuki H, et al. Promotion of mitochondrial biogenesis by necdin protects neurons against mitochondrial insults. Nat Commun. 2016;7:10943 pubmed publisher
|
Lakisic G, Lebreton A, Pourpre R, Wendling O, Libertini E, Radford E, et al. Role of the BAHD1 Chromatin-Repressive Complex in Placental Development and Regulation of Steroid Metabolism. PLoS Genet. 2016;12:e1005898 pubmed publisher
|
Krisko J, Begum N, Baker C, Foster J, Garcia J. APOBEC3G and APOBEC3F Act in Concert To Extinguish HIV-1 Replication. J Virol. 2016;90:4681-4695 pubmed publisher
|
Militi S, Maywood E, Sandate C, Chesham J, Barnard A, Parsons M, et al. Early doors (Edo) mutant mouse reveals the importance of period 2 (PER2) PAS domain structure for circadian pacemaking. Proc Natl Acad Sci U S A. 2016;113:2756-61 pubmed publisher
|
Maine E, Westcott J, Prechtl A, Dang T, Whitehurst A, Pearson G. The cancer-testis antigens SPANX-A/C/D and CTAG2 promote breast cancer invasion. Oncotarget. 2016;7:14708-26 pubmed publisher
|
Gawron D, Ndah E, Gevaert K, Van Damme P. Positional proteomics reveals differences in N-terminal proteoform stability. Mol Syst Biol. 2016;12:858 pubmed publisher
|
Prabhu A, Luu W, Sharpe L, Brown A. Cholesterol-mediated Degradation of 7-Dehydrocholesterol Reductase Switches the Balance from Cholesterol to Vitamin D Synthesis. J Biol Chem. 2016;291:8363-73 pubmed publisher
|
Bhide G, Fernandes N, Colley K. Sequence Requirements for Neuropilin-2 Recognition by ST8SiaIV and Polysialylation of Its O-Glycans. J Biol Chem. 2016;291:9444-57 pubmed publisher
|
Lehmann W, Mossmann D, Kleemann J, Mock K, Meisinger C, Brummer T, et al. ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types. Nat Commun. 2016;7:10498 pubmed publisher
|
Woehlbier U, Colombo A, Saaranen M, Pérez V, Ojeda J, Bustos F, et al. ALS-linked protein disulfide isomerase variants cause motor dysfunction. EMBO J. 2016;35:845-65 pubmed publisher
|
Kim N, Kim M, Sung P, Bae Y, Shin E, Yoo J. Interferon-inducible protein SCOTIN interferes with HCV replication through the autolysosomal degradation of NS5A. Nat Commun. 2016;7:10631 pubmed publisher
|
Hung V, Udeshi N, Lam S, Loh K, Cox K, Pedram K, et al. Spatially resolved proteomic mapping in living cells with the engineered peroxidase APEX2. Nat Protoc. 2016;11:456-75 pubmed publisher
|
Wei L, Zhao X. A new MCM modification cycle regulates DNA replication initiation. Nat Struct Mol Biol. 2016;23:209-16 pubmed publisher
|
Chatterjee G, Sankaranarayanan S, Guin K, Thattikota Y, Padmanabhan S, Siddharthan R, et al. Repeat-Associated Fission Yeast-Like Regional Centromeres in the Ascomycetous Budding Yeast Candida tropicalis. PLoS Genet. 2016;12:e1005839 pubmed publisher
|
Asadzadeh J, Neligan N, Kramer S, Labrador J. Tinman Regulates NetrinB in the Cardioblasts of the Drosophila Dorsal Vessel. PLoS ONE. 2016;11:e0148526 pubmed publisher
|
Luo W, Chen I, Chen Y, Alkam D, Wang Y, Semenza G. PRDX2 and PRDX4 are negative regulators of hypoxia-inducible factors under conditions of prolonged hypoxia. Oncotarget. 2016;7:6379-97 pubmed publisher
|
Jansen J, Cirak S, van Scherpenzeel M, Timal S, Reunert J, Rust S, et al. CCDC115 Deficiency Causes a Disorder of Golgi Homeostasis with Abnormal Protein Glycosylation. Am J Hum Genet. 2016;98:310-21 pubmed publisher
|
Jansen J, Timal S, van Scherpenzeel M, Michelakakis H, Vicogne D, Ashikov A, et al. TMEM199 Deficiency Is a Disorder of Golgi Homeostasis Characterized by Elevated Aminotransferases, Alkaline Phosphatase, and Cholesterol and Abnormal Glycosylation. Am J Hum Genet. 2016;98:322-30 pubmed publisher
|
DÃaz Barreiro A, Bernal Quirós M, Georg I, Marañón C, Alarcón Riquelme M, Castillejo López C. The SLE variant Ala71Thr of BLK severely decreases protein abundance and binding to BANK1 through impairment of the SH3 domain function. Genes Immun. 2016;17:128-38 pubmed publisher
|
Crawley S, Weck M, Grega Larson N, Shifrin D, Tyska M. ANKS4B Is Essential for Intermicrovillar Adhesion Complex Formation. Dev Cell. 2016;36:190-200 pubmed publisher
|
Santhanam A, Torricelli A, Wu J, Marino G, Wilson S. Differential expression of epithelial basement membrane components nidogens and perlecan in corneal stromal cells in vitro. Mol Vis. 2015;21:1318-27 pubmed
|
Heynen G, Nevedomskaya E, Palit S, Jagalur Basheer N, Lieftink C, Schlicker A, et al. Mastermind-Like 3 Controls Proliferation and Differentiation in Neuroblastoma. Mol Cancer Res. 2016;14:411-22 pubmed publisher
|
Rebbapragada I, Birkus G, Perry J, Xing W, Kwon H, Pflanz S. Molecular Determinants of GS-9620-Dependent TLR7 Activation. PLoS ONE. 2016;11:e0146835 pubmed publisher
|
Vais H, Mallilankaraman K, Mak D, Hoff H, Payne R, Tanis J, et al. EMRE Is a Matrix Ca(2+) Sensor that Governs Gatekeeping of the Mitochondrial Ca(2+) Uniporter. Cell Rep. 2016;14:403-410 pubmed publisher
|
McDonald P, Read K, Baker C, Anderson A, Powell M, Ballesteros Tato A, et al. IL-7 signalling represses Bcl-6 and the TFH gene program. Nat Commun. 2016;7:10285 pubmed publisher
|
Carroll B, Maetzel D, Maddocks O, Otten G, Ratcliff M, Smith G, et al. Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity. elife. 2016;5: pubmed publisher
|
Yu C, Liang J, Li J, Lee Y, Chang B, Su C, et al. Dengue Virus Impairs Mitochondrial Fusion by Cleaving Mitofusins. PLoS Pathog. 2015;11:e1005350 pubmed publisher
|
Gallego Ortega D, Ledger A, Roden D, Law A, Magenau A, Kikhtyak Z, et al. ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells. PLoS Biol. 2015;13:e1002330 pubmed publisher
|
Li R, Liao G, Nirujogi R, Pinto S, Shaw P, Huang T, et al. Phosphoproteomic Profiling Reveals Epstein-Barr Virus Protein Kinase Integration of DNA Damage Response and Mitotic Signaling. PLoS Pathog. 2015;11:e1005346 pubmed publisher
|
Trzeciecka A, Klossowski S, Bajor M, Zagozdzon R, Gaj P, Muchowicz A, et al. Dimeric peroxiredoxins are druggable targets in human Burkitt lymphoma. Oncotarget. 2016;7:1717-31 pubmed publisher
|
Faltermeier C, Drake J, Clark P, Smith B, Zong Y, Volpe C, et al. Functional screen identifies kinases driving prostate cancer visceral and bone metastasis. Proc Natl Acad Sci U S A. 2016;113:E172-81 pubmed publisher
|
Hansen C, Ng Y, Lam W, Plouffe S, Guan K. The Hippo pathway effectors YAP and TAZ promote cell growth by modulating amino acid signaling to mTORC1. Cell Res. 2015;25:1299-313 pubmed publisher
|
Barneda D, Planas Iglesias J, Gaspar M, Mohammadyani D, Prasannan S, Dormann D, et al. The brown adipocyte protein CIDEA promotes lipid droplet fusion via a phosphatidic acid-binding amphipathic helix. elife. 2015;4:e07485 pubmed publisher
|
Kim M, Kim M, Park S, Lee C, Lim D. Role of Angiomotin-like 2 mono-ubiquitination on YAP inhibition. EMBO Rep. 2016;17:64-78 pubmed publisher
|
Stadhouders R, Cico A, Stephen T, Thongjuea S, Kolovos P, Baymaz H, et al. Control of developmentally primed erythroid genes by combinatorial co-repressor actions. Nat Commun. 2015;6:8893 pubmed publisher
|
Luberg K, Park R, Aleksejeva E, Timmusk T. Novel transcripts reveal a complex structure of the human TRKA gene and imply the presence of multiple protein isoforms. BMC Neurosci. 2015;16:78 pubmed publisher
|
Freischmidt A, Schöpflin M, Feiler M, Fleck A, Ludolph A, Weishaupt J. Profilin 1 with the amyotrophic lateral sclerosis associated mutation T109M displays unaltered actin binding and does not affect the actin cytoskeleton. BMC Neurosci. 2015;16:77 pubmed publisher
|
Hu Z, Hu J, Shen W, Kraemer F, Azhar S. A Novel Role of Salt-Inducible Kinase 1 (SIK1) in the Post-Translational Regulation of Scavenger Receptor Class B Type 1 Activity. Biochemistry. 2015;54:6917-30 pubmed publisher
|
Maxfield K, Taus P, Corcoran K, Wooten J, Macion J, Zhou Y, et al. Comprehensive functional characterization of cancer-testis antigens defines obligate participation in multiple hallmarks of cancer. Nat Commun. 2015;6:8840 pubmed publisher
|
Casey J, Støve S, McGorrian C, Galvin J, Blenski M, Dunne A, et al. NAA10 mutation causing a novel intellectual disability syndrome with Long QT due to N-terminal acetyltransferase impairment. Sci Rep. 2015;5:16022 pubmed publisher
|
He W, Bai G, Zhou H, Wei N, White N, Lauer J, et al. CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase. Nature. 2015;526:710-4 pubmed publisher
|
Niemelä E, Verbeeren J, Singha P, Nurmi V, Frilander M. Evolutionarily conserved exon definition interactions with U11 snRNP mediate alternative splicing regulation on U11-48K and U11/U12-65K genes. RNA Biol. 2015;12:1256-64 pubmed publisher
|
van der Kant R, Jonker C, Wijdeven R, Bakker J, Janssen L, Klumperman J, et al. Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity. J Biol Chem. 2015;290:30280-90 pubmed publisher
|
Görtz D, Braun G, Maruta Y, Djudjaj S, van Roeyen C, Martin I, et al. Anti-interleukin-6 therapy through application of a monogenic protein inhibitor via gene delivery. Sci Rep. 2015;5:14685 pubmed publisher
|
Hu D, Gur M, Zhou Z, Gamper A, Hung M, Fujita N, et al. Interplay between arginine methylation and ubiquitylation regulates KLF4-mediated genome stability and carcinogenesis. Nat Commun. 2015;6:8419 pubmed publisher
|
Sun S, Reddy B, Irvine K. Localization of Hippo signalling complexes and Warts activation in vivo. Nat Commun. 2015;6:8402 pubmed publisher
|
Marks M, Pennimpede T, Lange L, Grote P, Herrmann B, Wittler L. Analysis of the Fam181 gene family during mouse development reveals distinct strain-specific expression patterns, suggesting a role in nervous system development and function. Gene. 2016;575:438-451 pubmed publisher
|
Eberle A, Jordán Pla A, Gañez Zapater A, Hessle V, Silberberg G, von Euler A, et al. An Interaction between RRP6 and SU(VAR)3-9 Targets RRP6 to Heterochromatin and Contributes to Heterochromatin Maintenance in Drosophila melanogaster. PLoS Genet. 2015;11:e1005523 pubmed publisher
|
Hardies K, de Kovel C, Weckhuysen S, Asselbergh B, Geuens T, Deconinck T, et al. Recessive mutations in SLC13A5 result in a loss of citrate transport and cause neonatal epilepsy, developmental delay and teeth hypoplasia. Brain. 2015;138:3238-50 pubmed publisher
|
Liu X, Dai F, Guo E, Li K, Ma L, Tian L, et al. 20-Hydroxyecdysone (20E) Primary Response Gene E93 Modulates 20E Signaling to Promote Bombyx Larval-Pupal Metamorphosis. J Biol Chem. 2015;290:27370-83 pubmed publisher
|
Baker C, Petkova P, Walker M, Flachs P, Mihola O, Trachtulec Z, et al. Multimer Formation Explains Allelic Suppression of PRDM9 Recombination Hotspots. PLoS Genet. 2015;11:e1005512 pubmed publisher
|
Kitatani K, Usui T, Sriraman S, Toyoshima M, Ishibashi M, Shigeta S, et al. Ceramide limits phosphatidylinositol-3-kinase C2β-controlled cell motility in ovarian cancer: potential of ceramide as a metastasis-suppressor lipid. Oncogene. 2016;35:2801-12 pubmed publisher
|
Komaba S, Coluccio L. Myosin 1b Regulates Amino Acid Transport by Associating Transporters with the Apical Plasma Membrane of Kidney Cells. PLoS ONE. 2015;10:e0138012 pubmed publisher
|
Hasan M, Fermaintt C, Gao N, Sakai T, Miyazaki T, Jiang S, et al. Cytosolic Nuclease TREX1 Regulates Oligosaccharyltransferase Activity Independent of Nuclease Activity to Suppress Immune Activation. Immunity. 2015;43:463-74 pubmed publisher
|
Cavaletto N, Luganini A, Gribaudo G. Inactivation of the Human Cytomegalovirus US20 Gene Hampers Productive Viral Replication in Endothelial Cells. J Virol. 2015;89:11092-106 pubmed publisher
|
McDermott S, Guo X, Carnes J, Stuart K. Differential Editosome Protein Function between Life Cycle Stages of Trypanosoma brucei. J Biol Chem. 2015;290:24914-31 pubmed publisher
|
Fasolo J, Im H, Snyder M. Probing High-density Functional Protein Microarrays to Detect Protein-protein Interactions. J Vis Exp. 2015;:e51872 pubmed publisher
|
Lee H, Park Y, Cho M, Chae S, Yoo Y, Kwon M, et al. The chromatin remodeller RSF1 is essential for PLK1 deposition and function at mitotic kinetochores. Nat Commun. 2015;6:7904 pubmed publisher
|
Chen S, Cao P, Dong N, Peng J, Zhang C, Wang H, et al. PCSK6-mediated corin activation is essential for normal blood pressure. Nat Med. 2015;21:1048-53 pubmed publisher
|
Pon J, Wong J, Saberi S, Alder O, Moksa M, Grace Cheng S, et al. MEF2B mutations in non-Hodgkin lymphoma dysregulate cell migration by decreasing MEF2B target gene activation. Nat Commun. 2015;6:7953 pubmed publisher
|
Li Y, Peng L, Seto E. Histone Deacetylase 10 Regulates the Cell Cycle G2/M Phase Transition via a Novel Let-7-HMGA2-Cyclin A2 Pathway. Mol Cell Biol. 2015;35:3547-65 pubmed publisher
|
Ohsawa Y, Takayama K, Nishimatsu S, Okada T, Fujino M, Fukai Y, et al. The Inhibitory Core of the Myostatin Prodomain: Its Interaction with Both Type I and II Membrane Receptors, and Potential to Treat Muscle Atrophy. PLoS ONE. 2015;10:e0133713 pubmed publisher
|
Khalil H, Loukili N, Regamey A, Cuesta Marbán A, Santori E, Huber M, et al. The caspase-3-p120-RasGAP module generates a NF-κB repressor in response to cellular stress. J Cell Sci. 2015;128:3502-13 pubmed publisher
|
Papke C, Tsunezumi J, Ringuette L, Nagaoka H, Terajima M, Yamashiro Y, et al. Loss of fibulin-4 disrupts collagen synthesis and maturation: implications for pathology resulting from EFEMP2 mutations. Hum Mol Genet. 2015;24:5867-79 pubmed publisher
|
Graham D, Becker C, Doan A, Goel G, Villablanca E, Knights D, et al. Functional genomics identifies negative regulatory nodes controlling phagocyte oxidative burst. Nat Commun. 2015;6:7838 pubmed publisher
|
Murray A, Chen W, Antonopoulos A, Hanson S, Wiseman R, Dell A, et al. Enhanced Aromatic Sequons Increase Oligosaccharyltransferase Glycosylation Efficiency and Glycan Homogeneity. Chem Biol. 2015;22:1052-62 pubmed publisher
|
Ãdám C, Fekete A, BÅ‘gel G, Németh Z, TÅ‘kési N, Ovádi J, et al. Accumulation of the PX domain mutant Frank-ter Haar syndrome protein Tks4 in aggresomes. Cell Commun Signal. 2015;13:33 pubmed publisher
|
Macvicar T, Mannack L, Lees R, Lane J. Targeted siRNA Screens Identify ER-to-Mitochondrial Calcium Exchange in Autophagy and Mitophagy Responses in RPE1 Cells. Int J Mol Sci. 2015;16:13356-80 pubmed publisher
|
Kaur G, Pinggera A, Ortner N, Lieb A, Sinnegger Brauns M, Yarov Yarovoy V, et al. A Polybasic Plasma Membrane Binding Motif in the I-II Linker Stabilizes Voltage-gated CaV1.2 Calcium Channel Function. J Biol Chem. 2015;290:21086-100 pubmed publisher
|
Iwahori S, Hakki M, Chou S, Kalejta R. Molecular Determinants for the Inactivation of the Retinoblastoma Tumor Suppressor by the Viral Cyclin-dependent Kinase UL97. J Biol Chem. 2015;290:19666-80 pubmed publisher
|
Whiting J, Nygren P, Tunquist B, Langeberg L, Seternes O, Scott J. Protein Kinase A Opposes the Phosphorylation-dependent Recruitment of Glycogen Synthase Kinase 3β to A-kinase Anchoring Protein 220. J Biol Chem. 2015;290:19445-57 pubmed publisher
|
Schmidt S, Moncada M, Burger S, Geyer J. Expression, sorting and transport studies for the orphan carrier SLC10A4 in neuronal and non-neuronal cell lines and in Xenopus laevis oocytes. BMC Neurosci. 2015;16:35 pubmed publisher
|
Song H, Pu J, Wang L, Wu L, Xiao J, Liu Q, et al. ATG16L1 phosphorylation is oppositely regulated by CSNK2/casein kinase 2 and PPP1/protein phosphatase 1 which determines the fate of cardiomyocytes during hypoxia/reoxygenation. Autophagy. 2015;11:1308-25 pubmed publisher
|
Panneer Selvam S, De Palma R, Oaks J, Oleinik N, Peterson Y, Stahelin R, et al. Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation. Sci Signal. 2015;8:ra58 pubmed publisher
|
May M, Hwang K, MILES J, Williams C, Niranjan T, Kahler S, et al. ZC4H2, an XLID gene, is required for the generation of a specific subset of CNS interneurons. Hum Mol Genet. 2015;24:4848-61 pubmed publisher
|
Sandau M, Goodman J, Thomas A, Rucker J, Rawson N. A functional comparison of the domestic cat bitter receptors Tas2r38 and Tas2r43 with their human orthologs. BMC Neurosci. 2015;16:33 pubmed publisher
|
Ting P, Johnson C, Fang C, Cao X, Graeber T, Mattos C, et al. Tyrosine phosphorylation of RAS by ABL allosterically enhances effector binding. FASEB J. 2015;29:3750-61 pubmed publisher
|
Grice S, Sleigh J, Motley W, Liu J, Burgess R, Talbot K, et al. Dominant, toxic gain-of-function mutations in gars lead to non-cell autonomous neuropathology. Hum Mol Genet. 2015;24:4397-406 pubmed publisher
|
Ibsen M, Gad H, Andersen L, Hornung V, Julkunen I, Sarkar S, et al. Structural and functional analysis reveals that human OASL binds dsRNA to enhance RIG-I signaling. Nucleic Acids Res. 2015;43:5236-48 pubmed publisher
|
Pilli V, Gupta K, Kotha B, Aradhyam G. Snail-mediated Cripto-1 repression regulates the cell cycle and epithelial-mesenchymal transition-related gene expression. FEBS Lett. 2015;589:1249-56 pubmed publisher
|
Tebbi A, Guittet O, Tuphile K, Cabrié A, Lepoivre M. Caspase-dependent Proteolysis of Human Ribonucleotide Reductase Small Subunits R2 and p53R2 during Apoptosis. J Biol Chem. 2015;290:14077-90 pubmed publisher
|
Koppel I, Tuvikene J, Lekk I, Timmusk T. Efficient use of a translation start codon in BDNF exon I. J Neurochem. 2015;134:1015-25 pubmed publisher
|
Nakayama T, Al Maawali A, El Quessny M, Rajab A, Khalil S, Stoler J, et al. Mutations in PYCR2, Encoding Pyrroline-5-Carboxylate Reductase 2, Cause Microcephaly and Hypomyelination. Am J Hum Genet. 2015;96:709-19 pubmed publisher
|
Okatsu K, Koyano F, Kimura M, Kosako H, Saeki Y, Tanaka K, et al. Phosphorylated ubiquitin chain is the genuine Parkin receptor. J Cell Biol. 2015;209:111-28 pubmed publisher
|
Dayer C, Stamenkovic I. Recruitment of Matrix Metalloproteinase-9 (MMP-9) to the Fibroblast Cell Surface by Lysyl Hydroxylase 3 (LH3) Triggers Transforming Growth Factor-β (TGF-β) Activation and Fibroblast Differentiation. J Biol Chem. 2015;290:13763-78 pubmed publisher
|
Eisner A, Pazyra Murphy M, Durresi E, Zhou P, Zhao X, Chadwick E, et al. The Eya1 phosphatase promotes Shh signaling during hindbrain development and oncogenesis. Dev Cell. 2015;33:22-35 pubmed publisher
|
Cui J, Xiao J, Tagliabracci V, Wen J, Rahdar M, Dixon J. A secretory kinase complex regulates extracellular protein phosphorylation. elife. 2015;4:e06120 pubmed publisher
|
Aguilera Ã, González Sancho J, Zazo S, Rincón R, Fernández A, Tapia O, et al. Nuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer. Oncotarget. 2015;6:5903-17 pubmed
|
Friebe S, Deuquet J, van der Goot F. Differential dependence on N-glycosylation of anthrax toxin receptors CMG2 and TEM8. PLoS ONE. 2015;10:e0119864 pubmed publisher
|
Fjeld K, Weiss F, Lasher D, Rosendahl J, Chen J, Johansson B, et al. A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis. Nat Genet. 2015;47:518-522 pubmed publisher
|
Lan X, Koutelou E, Schibler A, Chen Y, Grant P, Dent S. Poly(Q) Expansions in ATXN7 Affect Solubility but Not Activity of the SAGA Deubiquitinating Module. Mol Cell Biol. 2015;35:1777-87 pubmed publisher
|
Goel S, Palmkvist M, Moll K, Joannin N, Lara P, Akhouri R, et al. RIFINs are adhesins implicated in severe Plasmodium falciparum malaria. Nat Med. 2015;21:314-7 pubmed publisher
|
Wang K, Chen Y, Ferguson S, Leach R. MTA1 and MTA3 Regulate HIF1a Expression in Hypoxia-Treated Human Trophoblast Cell Line HTR8/Svneo. Med J Obstet Gynecol. 2013;1: pubmed
|
Wang L, Burmeister B, Johnson K, Baillie G, Karginov A, Skidgel R, et al. UCR1C is a novel activator of phosphodiesterase 4 (PDE4) long isoforms and attenuates cardiomyocyte hypertrophy. Cell Signal. 2015;27:908-22 pubmed publisher
|
Kärblane K, Gerassimenko J, Nigul L, Piirsoo A, Smialowska A, Vinkel K, et al. ABCE1 is a highly conserved RNA silencing suppressor. PLoS ONE. 2015;10:e0116702 pubmed publisher
|
Kathania M, Zeng M, Yadav V, Moghaddam S, Yang B, Venuprasad K. Ndfip1 regulates itch ligase activity and airway inflammation via UbcH7. J Immunol. 2015;194:2160-7 pubmed publisher
|
Sia D, Losic B, Moeini A, Cabellos L, Hao K, Revill K, et al. Massive parallel sequencing uncovers actionable FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma. Nat Commun. 2015;6:6087 pubmed publisher
|
Mauger O, Klinck R, Chabot B, Muchardt C, Allemand E, Batsché E. Alternative splicing regulates the expression of G9A and SUV39H2 methyltransferases, and dramatically changes SUV39H2 functions. Nucleic Acids Res. 2015;43:1869-82 pubmed publisher
|
Takahashi C, Kusakabe M, Suzuki T, Miyatake K, Nishida E. mab21-l3 regulates cell fate specification of multiciliate cells and ionocytes. Nat Commun. 2015;6:6017 pubmed publisher
|
Huber R, Lucas J, Gomez Sarosi L, Coleman I, Zhao S, Coleman R, et al. DNA damage induces GDNF secretion in the tumor microenvironment with paracrine effects promoting prostate cancer treatment resistance. Oncotarget. 2015;6:2134-47 pubmed
|
Mendoza E, Tokarev K, Düring D, Retamosa E, Weiss M, Arpenik N, et al. Differential coexpression of FoxP1, FoxP2, and FoxP4 in the Zebra Finch (Taeniopygia guttata) song system. J Comp Neurol. 2015;523:1318-40 pubmed publisher
|
Inagaki T, Iwasaki S, Matsumura Y, Kawamura T, Tanaka T, Abe Y, et al. The FBXL10/KDM2B scaffolding protein associates with novel polycomb repressive complex-1 to regulate adipogenesis. J Biol Chem. 2015;290:4163-77 pubmed publisher
|
Méreau A, Anquetil V, Lerivray H, Viet J, Schirmer C, Audic Y, et al. A posttranscriptional mechanism that controls Ptbp1 abundance in the Xenopus epidermis. Mol Cell Biol. 2015;35:758-68 pubmed publisher
|
Myklebust L, Van Damme P, Støve S, Dörfel M, Abboud A, Kalvik T, et al. Biochemical and cellular analysis of Ogden syndrome reveals downstream Nt-acetylation defects. Hum Mol Genet. 2015;24:1956-76 pubmed publisher
|
Menon M, Chuang P, Li Z, Wei C, Zhang W, Luan Y, et al. Intronic locus determines SHROOM3 expression and potentiates renal allograft fibrosis. J Clin Invest. 2015;125:208-21 pubmed publisher
|
Wang H, Lv G, Zhou X, Li Z, Liu X, Yu X, et al. Requirement of HIV-1 Vif C-terminus for Vif-CBF-β interaction and assembly of CUL5-containing E3 ligase. BMC Microbiol. 2014;14:290 pubmed publisher
|
Garvalov B, Foss F, Henze A, Bethani I, Gräf Höchst S, Singh D, et al. PHD3 regulates EGFR internalization and signalling in tumours. Nat Commun. 2014;5:5577 pubmed publisher
|
Lam S, Martell J, Kamer K, Deerinck T, Ellisman M, Mootha V, et al. Directed evolution of APEX2 for electron microscopy and proximity labeling. Nat Methods. 2015;12:51-4 pubmed publisher
|
Marques Howarth M, Simpson D, Ngok S, Nieves B, Chen R, Siprashvili Z, et al. Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis. J Clin Invest. 2014;124:5275-90 pubmed publisher
|
Voss M, Künzel U, Higel F, Kuhn P, Colombo A, Fukumori A, et al. Shedding of glycan-modifying enzymes by signal peptide peptidase-like 3 (SPPL3) regulates cellular N-glycosylation. EMBO J. 2014;33:2890-905 pubmed publisher
|
Olmsted Z, Colliver A, Riehlman T, Paluh J. Kinesin-14 and kinesin-5 antagonistically regulate microtubule nucleation by γ-TuRC in yeast and human cells. Nat Commun. 2014;5:5339 pubmed publisher
|
Fang N, Chan G, Zhu M, Comyn S, Persaud A, Deshaies R, et al. Rsp5/Nedd4 is the main ubiquitin ligase that targets cytosolic misfolded proteins following heat stress. Nat Cell Biol. 2014;16:1227-37 pubmed publisher
|
Sabag A, Smolkin T, Mumblat Y, Ueffing M, Kessler O, Gloeckner C, et al. The role of the plexin-A2 receptor in Sema3A and Sema3B signal transduction. J Cell Sci. 2014;127:5240-52 pubmed publisher
|
Couthouis J, Raphael A, Daneshjou R, Gitler A. Targeted exon capture and sequencing in sporadic amyotrophic lateral sclerosis. PLoS Genet. 2014;10:e1004704 pubmed publisher
|
Pereira L, Pinto R, Silva D, Moreira A, Beitzinger C, Oliveira P, et al. Intracellular trafficking of AIP56, an NF-κB-cleaving toxin from Photobacterium damselae subsp. piscicida. Infect Immun. 2014;82:5270-85 pubmed publisher
|
Kumar A, Varendi K, Peränen J, Andressoo J. Tristetraprolin is a novel regulator of BDNF. Springerplus. 2014;3:502 pubmed publisher
|
Gabaev I, Elbasani E, Ameres S, Steinbrück L, Stanton R, Döring M, et al. Expression of the human cytomegalovirus UL11 glycoprotein in viral infection and evaluation of its effect on virus-specific CD8 T cells. J Virol. 2014;88:14326-39 pubmed publisher
|
Balasuriya D, D Sa L, Talker R, Dupuis E, Maurin F, Martin P, et al. A direct interaction between the sigma-1 receptor and the hERG voltage-gated K+ channel revealed by atomic force microscopy and homogeneous time-resolved fluorescence (HTRF®). J Biol Chem. 2014;289:32353-63 pubmed publisher
|
Wang S, Celic I, Choi S, Riccomagno M, Wang Q, Sun L, et al. Dlg5 regulates dendritic spine formation and synaptogenesis by controlling subcellular N-cadherin localization. J Neurosci. 2014;34:12745-61 pubmed publisher
|
Van Damme P, Plasman K, Vandemoortele G, Jonckheere V, Maurer Stroh S, Gevaert K. Importance of extended protease substrate recognition motifs in steering BNIP-2 cleavage by human and mouse granzymes B. BMC Biochem. 2014;15:21 pubmed publisher
|
Wang F, Soprano K, Soprano D. Role of Acinus in regulating retinoic acid-responsive gene pre-mRNA splicing. J Cell Physiol. 2015;230:791-801 pubmed publisher
|
Kast J, Hanecker P, Beaufort N, Giese A, Joutel A, Dichgans M, et al. Sequestration of latent TGF-β binding protein 1 into CADASIL-related Notch3-ECD deposits. Acta Neuropathol Commun. 2014;2:96 pubmed publisher
|
Zhang Y, Jansen West K, Xu Y, Gendron T, Bieniek K, Lin W, et al. Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress. Acta Neuropathol. 2014;128:505-24 pubmed publisher
|
Torsvik J, Johansson B, Dalva M, Marie M, Fjeld K, Johansson S, et al. Endocytosis of secreted carboxyl ester lipase in a syndrome of diabetes and pancreatic exocrine dysfunction. J Biol Chem. 2014;289:29097-111 pubmed publisher
|
Cherepanova N, Shrimal S, Gilmore R. Oxidoreductase activity is necessary for N-glycosylation of cysteine-proximal acceptor sites in glycoproteins. J Cell Biol. 2014;206:525-39 pubmed publisher
|
He Q, Wen D, Jia Q, Cui C, Wang J, Palli S, et al. Heat shock protein 83 (Hsp83) facilitates methoprene-tolerant (Met) nuclear import to modulate juvenile hormone signaling. J Biol Chem. 2014;289:27874-85 pubmed publisher
|
Xu M, Nagati J, Xie J, Li J, Walters H, Moon Y, et al. An acetate switch regulates stress erythropoiesis. Nat Med. 2014;20:1018-26 pubmed publisher
|
Bosch J, Sumabat T, Hafezi Y, Pellock B, Gandhi K, Hariharan I. The Drosophila F-box protein Fbxl7 binds to the protocadherin fat and regulates Dachs localization and Hippo signaling. elife. 2014;3:e03383 pubmed publisher
|
Bartman C, Egelston J, Ren X, Das R, Phiel C. A simple and efficient method for transfecting mouse embryonic stem cells using polyethylenimine. Exp Cell Res. 2015;330:178-85 pubmed publisher
|
Vilar M, Sung T, Chen Z, García Carpio I, Fernandez E, Xu J, et al. Heterodimerization of p45-p75 modulates p75 signaling: structural basis and mechanism of action. PLoS Biol. 2014;12:e1001918 pubmed publisher
|
Wang F, Wendling K, Soprano K, Soprano D. The SAP motif and C-terminal RS- and RD/E-rich region influences the sub-nuclear localization of Acinus isoforms. J Cell Biochem. 2014;115:2165-74 pubmed publisher
|
Marusyk A, Tabassum D, Altrock P, Almendro V, Michor F, Polyak K. Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity. Nature. 2014;514:54-8 pubmed publisher
|
Lima W, Vickers T, Nichols J, Li C, Crooke S. Defining the factors that contribute to on-target specificity of antisense oligonucleotides. PLoS ONE. 2014;9:e101752 pubmed publisher
|
Smith C, Matheson T, Trombly D, Sun X, Campeau E, Han X, et al. A separable domain of the p150 subunit of human chromatin assembly factor-1 promotes protein and chromosome associations with nucleoli. Mol Biol Cell. 2014;25:2866-81 pubmed publisher
|
Ghiaci P, Norbeck J, Larsson C. 2-Butanol and butanone production in Saccharomyces cerevisiae through combination of a B12 dependent dehydratase and a secondary alcohol dehydrogenase using a TEV-based expression system. PLoS ONE. 2014;9:e102774 pubmed publisher
|
Rauskolb C, Sun S, Sun G, Pan Y, Irvine K. Cytoskeletal tension inhibits Hippo signaling through an Ajuba-Warts complex. Cell. 2014;158:143-156 pubmed publisher
|
Bernatik O, Sedova K, Schille C, Ganji R, Cervenka I, Trantirek L, et al. Functional analysis of dishevelled-3 phosphorylation identifies distinct mechanisms driven by casein kinase 1ϵ and frizzled5. J Biol Chem. 2014;289:23520-33 pubmed publisher
|
Zheng X, Zhai B, Koivunen P, Shin S, Lu G, Liu J, et al. Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase. Genes Dev. 2014;28:1429-44 pubmed publisher
|
Petrini I, Meltzer P, Kim I, Lucchi M, Park K, Fontanini G, et al. A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors. Nat Genet. 2014;46:844-9 pubmed publisher
|
Jefferson M, Donaszi Ivanov A, Pollen S, Dalmay T, Saalbach G, Powell P. Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex. J Virol. 2014;88:10340-53 pubmed publisher
|
Chew Y, Fan X, Götz J, Nicholas H. Regulation of age-related structural integrity in neurons by protein with tau-like repeats (PTL-1) is cell autonomous. Sci Rep. 2014;4:5185 pubmed publisher
|
Yücel D, Hoe M, Llamosas E, Kant S, Jamieson C, Young P, et al. SUMV-1 antagonizes the activity of synthetic multivulva genes in Caenorhabditis elegans. Dev Biol. 2014;392:266-82 pubmed publisher
|
Zhou H, Wan B, Grubisic I, Kaplan T, Tjian R. TAF7L modulates brown adipose tissue formation. elife. 2014;3: pubmed publisher
|
Hait N, Wise L, Allegood J, O Brien M, Avni D, Reeves T, et al. Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory. Nat Neurosci. 2014;17:971-80 pubmed publisher
|
Ugbode C, Hirst W, Rattray M. Neuronal influences are necessary to produce mitochondrial co-localization with glutamate transporters in astrocytes. J Neurochem. 2014;130:668-77 pubmed publisher
|
Wang H, Liu B, Liu X, Li Z, Yu X, Zhang W. Identification of HIV-1 Vif regions required for CBF-? interaction and APOBEC3 suppression. PLoS ONE. 2014;9:e95738 pubmed publisher
|
Lee C, Freinkman E, Sabatini D, Ploegh H. The protein synthesis inhibitor blasticidin s enters mammalian cells via leucine-rich repeat-containing protein 8D. J Biol Chem. 2014;289:17124-31 pubmed publisher
|
Lo D, Zhang Y, Dai M, Sun X, Zeng S, Lu H. Nucleostemin stabilizes ARF by inhibiting the ubiquitin ligase ULF. Oncogene. 2015;34:1688-97 pubmed publisher
|
Mitra S, G mez Raja J, Larriba G, Dubey D, Sanyal K. Rad51-Rad52 mediated maintenance of centromeric chromatin in Candida albicans. PLoS Genet. 2014;10:e1004344 pubmed publisher
|
Yamanaka T, Wong H, Tosaki A, Bauer P, Wada K, Kurosawa M, et al. Large-scale RNA interference screening in mammalian cells identifies novel regulators of mutant huntingtin aggregation. PLoS ONE. 2014;9:e93891 pubmed publisher
|
Ogara M, Belluscio L, de la Fuente V, Berardino B, Sonzogni S, Byk L, et al. CDK5-mediated phosphorylation of p19INK4d avoids DNA damage-induced neurodegeneration in mouse hippocampus and prevents loss of cognitive functions. Biochim Biophys Acta. 2014;1843:1309-24 pubmed publisher
|
Tsai S, Chang D, Hong C, Xia P, Senadheera D, Trump L, et al. Induced overexpression of OCT4A in human embryonic stem cells increases cloning efficiency. Am J Physiol Cell Physiol. 2014;306:C1108-18 pubmed publisher
|
Nguyen V, Chen J, Petrus M, Goldman C, Kruhlak M, Bamford R, et al. A new domain in the Toll/IL-1R domain-containing adaptor inducing interferon-β factor protein amino terminus is important for tumor necrosis factor-α receptor-associated factor 3 association, protein stabilization and interferon signaling. J Innate Immun. 2014;6:377-93 pubmed publisher
|
Imamura K, Maeda S, Kawamura I, Matsuyama K, Shinohara N, Yahiro Y, et al. Human immunodeficiency virus type 1 enhancer-binding protein 3 is essential for the expression of asparagine-linked glycosylation 2 in the regulation of osteoblast and chondrocyte differentiation. J Biol Chem. 2014;289:9865-79 pubmed publisher
|
Gough S, Lee F, Yang F, Walker R, Zhu Y, Pineda M, et al. NUP98-PHF23 is a chromatin-modifying oncoprotein that causes a wide array of leukemias sensitive to inhibition of PHD histone reader function. Cancer Discov. 2014;4:564-77 pubmed publisher
|
Kozlitina J, Smagris E, Stender S, Nordestgaard B, Zhou H, Tybjærg Hansen A, et al. Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease. Nat Genet. 2014;46:352-6 pubmed publisher
|
Cuartero S, Fresán U, Reina O, Planet E, Espinàs M. Ibf1 and Ibf2 are novel CP190-interacting proteins required for insulator function. EMBO J. 2014;33:637-47 pubmed publisher
|
Steinhauf D, Rodriguez A, Vlachakis D, Virgo G, Maksimov V, Kristell C, et al. Silencing motifs in the Clr2 protein from fission yeast, Schizosaccharomyces pombe. PLoS ONE. 2014;9:e86948 pubmed publisher
|
Zhu D, Hölz S, Metzger E, Pavlovic M, Jandausch A, Jilg C, et al. Lysine-specific demethylase 1 regulates differentiation onset and migration of trophoblast stem cells. Nat Commun. 2014;5:3174 pubmed publisher
|
Evans S, SchOn A, Gao Q, Han X, Zhou X, Freire E, et al. HIV-1 Vif N-terminal motif is required for recruitment of Cul5 to suppress APOBEC3. Retrovirology. 2014;11:4 pubmed publisher
|
Maxson J, Luty S, Macmaniman J, Abel M, Druker B, Tyner J. Ligand independence of the T618I mutation in the colony-stimulating factor 3 receptor (CSF3R) protein results from loss of O-linked glycosylation and increased receptor dimerization. J Biol Chem. 2014;289:5820-7 pubmed publisher
|
Myatt S, Kongsema M, Man C, Kelly D, Gomes A, Khongkow P, et al. SUMOylation inhibits FOXM1 activity and delays mitotic transition. Oncogene. 2014;33:4316-29 pubmed publisher
|
Balko J, Giltnane J, Wang K, Schwarz L, Young C, Cook R, et al. Molecular profiling of the residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets. Cancer Discov. 2014;4:232-45 pubmed publisher
|
Larman H, Liang A, Elledge S, Zhu J. Discovery of protein interactions using parallel analysis of translated ORFs (PLATO). Nat Protoc. 2014;9:90-103 pubmed publisher
|
Kim I, Wang Y, Park K, Tang Y, Teoh J, Vinson J, et al. β-arrestin1-biased β1-adrenergic receptor signaling regulates microRNA processing. Circ Res. 2014;114:833-44 pubmed publisher
|
Clement L, Macé C, Avila Casado C, Joles J, Kersten S, Chugh S. Circulating angiopoietin-like 4 links proteinuria with hypertriglyceridemia in nephrotic syndrome. Nat Med. 2014;20:37-46 pubmed publisher
|
Walker A, Soo K, Sundaramoorthy V, Parakh S, Ma Y, Farg M, et al. ALS-associated TDP-43 induces endoplasmic reticulum stress, which drives cytoplasmic TDP-43 accumulation and stress granule formation. PLoS ONE. 2013;8:e81170 pubmed publisher
|
Choi J, Landrette S, Wang T, Evans P, Bacchiocchi A, Bjornson R, et al. Identification of PLX4032-resistance mechanisms and implications for novel RAF inhibitors. Pigment Cell Melanoma Res. 2014;27:253-62 pubmed publisher
|
Boisvert R, Rego M, Azzinaro P, Mauro M, Howlett N. Coordinate nuclear targeting of the FANCD2 and FANCI proteins via a FANCD2 nuclear localization signal. PLoS ONE. 2013;8:e81387 pubmed publisher
|
Forteza R, Wald F, Mashukova A, Kozhekbaeva Z, SALAS P. Par-complex aPKC and Par3 cross-talk with innate immunity NF-κB pathway in epithelial cells. Biol Open. 2013;2:1264-9 pubmed publisher
|
Johannessen C, Johnson L, Piccioni F, Townes A, Frederick D, Donahue M, et al. A melanocyte lineage program confers resistance to MAP kinase pathway inhibition. Nature. 2013;504:138-42 pubmed publisher
|
Bar Shir A, Liu G, Greenberg M, Bulte J, Gilad A. Synthesis of a probe for monitoring HSV1-tk reporter gene expression using chemical exchange saturation transfer MRI. Nat Protoc. 2013;8:2380-91 pubmed publisher
|
Sato S, Zhao Y, Imai M, Simister P, Feller S, Trackman P, et al. Inhibition of CIN85-mediated invasion by a novel SH3 domain binding motif in the lysyl oxidase propeptide. PLoS ONE. 2013;8:e77288 pubmed publisher
|
Mahadevan S, Wen S, Wan Y, Peng H, Otta S, Liu Z, et al. NLRP7 affects trophoblast lineage differentiation, binds to overexpressed YY1 and alters CpG methylation. Hum Mol Genet. 2014;23:706-16 pubmed publisher
|
Horiuchi K, Kawamura T, Iwanari H, Ohashi R, Naito M, Kodama T, et al. Identification of Wilms' tumor 1-associating protein complex and its role in alternative splicing and the cell cycle. J Biol Chem. 2013;288:33292-302 pubmed publisher
|
Oliveira C, Querido B, Sluijter M, de Groot A, van der Zee R, Rabelink M, et al. New role of signal peptide peptidase to liberate C-terminal peptides for MHC class I presentation. J Immunol. 2013;191:4020-8 pubmed publisher
|
Wiradjaja F, Cottle D, Jones L, Smyth I. Regulation of PDGFC signalling and extracellular matrix composition by FREM1 in mice. Dis Model Mech. 2013;6:1426-33 pubmed publisher
|
Himeda C, Barro M, Emerson C. Pax3 synergizes with Gli2 and Zic1 in transactivating the Myf5 epaxial somite enhancer. Dev Biol. 2013;383:7-14 pubmed publisher
|
Tenten V, Menzel S, Kunter U, Sicking E, van Roeyen C, Sanden S, et al. Albumin is recycled from the primary urine by tubular transcytosis. J Am Soc Nephrol. 2013;24:1966-80 pubmed publisher
|
Tiwari A, Schneider M, Fiorino A, Haider R, Okoniewski M, Roschitzki B, et al. Early insights into the function of KIAA1199, a markedly overexpressed protein in human colorectal tumors. PLoS ONE. 2013;8:e69473 pubmed publisher
|
Fekete A, Bogel G, Pesti S, Péterfi Z, Geiszt M, Buday L. EGF regulates tyrosine phosphorylation and membrane-translocation of the scaffold protein Tks5. J Mol Signal. 2013;8:8 pubmed publisher
|
McIlroy G, Földi I, Aurikko J, Wentzell J, Lim M, Fenton J, et al. Toll-6 and Toll-7 function as neurotrophin receptors in the Drosophila melanogaster CNS. Nat Neurosci. 2013;16:1248-56 pubmed publisher
|
Mason J, Das I, Arlt M, Patel N, Kraftson S, Glover T, et al. The SNM1B/APOLLO DNA nuclease functions in resolution of replication stress and maintenance of common fragile site stability. Hum Mol Genet. 2013;22:4901-13 pubmed publisher
|
Nishimoto Y, Nakagawa S, Hirose T, Okano H, Takao M, Shibata S, et al. The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis. Mol Brain. 2013;6:31 pubmed publisher
|
Han X, Poon R. Critical differences between isoforms of securin reveal mechanisms of separase regulation. Mol Cell Biol. 2013;33:3400-15 pubmed publisher
|
Nishioka C, Ikezoe T, Yang J, Nobumoto A, Kataoka S, Tsuda M, et al. CD82 regulates STAT5/IL-10 and supports survival of acute myelogenous leukemia cells. Int J Cancer. 2014;134:55-64 pubmed publisher
|
Balasuriya D, Goetze T, Barrera N, Stewart A, Suzuki Y, Edwardson J. ?-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) and N-methyl-D-aspartate (NMDA) receptors adopt different subunit arrangements. J Biol Chem. 2013;288:21987-98 pubmed publisher
|
Agra N, Cidre F, GarcÃa GarcÃa L, de la Parra J, Alonso J. Lysyl oxidase is downregulated by the EWS/FLI1 oncoprotein and its propeptide domain displays tumor supressor activities in Ewing sarcoma cells. PLoS ONE. 2013;8:e66281 pubmed publisher
|
Jain T, Wager Miller J, Mackie K, Straiker A. Diacylglycerol lipase? (DAGL?) and DAGL? cooperatively regulate the production of 2-arachidonoyl glycerol in autaptic hippocampal neurons. Mol Pharmacol. 2013;84:296-302 pubmed publisher
|
Frazier S, Cohen B, Lester H. An engineered glutamate-gated chloride (GluCl) channel for sensitive, consistent neuronal silencing by ivermectin. J Biol Chem. 2013;288:21029-42 pubmed publisher
|
Sato T, Kaneda A, Tsuji S, Isagawa T, Yamamoto S, Fujita T, et al. PRC2 overexpression and PRC2-target gene repression relating to poorer prognosis in small cell lung cancer. Sci Rep. 2013;3:1911 pubmed publisher
|
Terweij M, van Welsem T, van Deventer S, Verzijlbergen K, Menendez Benito V, Ontoso D, et al. Recombination-induced tag exchange (RITE) cassette series to monitor protein dynamics in Saccharomyces cerevisiae. G3 (Bethesda). 2013;3:1261-72 pubmed publisher
|
Chowdhury S, Chen Y, Yao T, Ajami K, Wang X, Popov Y, et al. Regulation of dipeptidyl peptidase 8 and 9 expression in activated lymphocytes and injured liver. World J Gastroenterol. 2013;19:2883-93 pubmed publisher
|
Shin H, Reich N. Dynamic trafficking of STAT5 depends on an unconventional nuclear localization signal. J Cell Sci. 2013;126:3333-43 pubmed publisher
|
Soldano A, Okray Z, Janovská P, Tmejová K, Reynaud E, Claeys A, et al. The Drosophila homologue of the amyloid precursor protein is a conserved modulator of Wnt PCP signaling. PLoS Biol. 2013;11:e1001562 pubmed publisher
|
Oku S, Takahashi N, Fukata Y, Fukata M. In silico screening for palmitoyl substrates reveals a role for DHHC1/3/10 (zDHHC1/3/11)-mediated neurochondrin palmitoylation in its targeting to Rab5-positive endosomes. J Biol Chem. 2013;288:19816-29 pubmed publisher
|
Viswanathan J, Haapasalo A, Kurkinen K, Natunen T, Mäkinen P, Bertram L, et al. Ubiquilin-1 modulates ?-secretase-mediated ?-site cleavage in neuronal cells. Biochemistry. 2013;52:3899-912 pubmed publisher
|
Bubenik J, Miniard A, Driscoll D. Alternative transcripts and 3'UTR elements govern the incorporation of selenocysteine into selenoprotein S. PLoS ONE. 2013;8:e62102 pubmed publisher
|
Michaloglou C, Lehmann W, Martin T, Delaunay C, Hueber A, Barys L, et al. The tyrosine phosphatase PTPN14 is a negative regulator of YAP activity. PLoS ONE. 2013;8:e61916 pubmed publisher
|
Morrison J, Laurent Rolle M, Maestre A, Rajsbaum R, Pisanelli G, Simon V, et al. Dengue virus co-opts UBR4 to degrade STAT2 and antagonize type I interferon signaling. PLoS Pathog. 2013;9:e1003265 pubmed publisher
|
Chew Y, Fan X, Götz J, Nicholas H. PTL-1 regulates neuronal integrity and lifespan in C. elegans. J Cell Sci. 2013;126:2079-91 pubmed publisher
|
Cheng J, Rozenblatt Rosen O, Paulson K, Nghiem P, DeCaprio J. Merkel cell polyomavirus large T antigen has growth-promoting and inhibitory activities. J Virol. 2013;87:6118-26 pubmed publisher
|
Zhu J, Larman H, Gao G, Somwar R, Zhang Z, Laserson U, et al. Protein interaction discovery using parallel analysis of translated ORFs (PLATO). Nat Biotechnol. 2013;31:331-334 pubmed publisher
|
Ahmed J, Ali R, Warr N, Wilson H, Bellchambers H, Barratt K, et al. A murine Zic3 transcript with a premature termination codon evades nonsense-mediated decay during axis formation. Dis Model Mech. 2013;6:755-67 pubmed publisher
|
Orenstein S, Kuo S, Tasset I, Arias E, Koga H, Fernandez Carasa I, et al. Interplay of LRRK2 with chaperone-mediated autophagy. Nat Neurosci. 2013;16:394-406 pubmed publisher
|
Ling L, Voskas D, Woodgett J. Activation of PDK-1 maintains mouse embryonic stem cell self-renewal in a PKB-dependent manner. Oncogene. 2013;32:5397-408 pubmed publisher
|
Christmann M, Schmaler T, Gordon C, Huang X, Bayram Ö, Schinke J, et al. Control of multicellular development by the physically interacting deneddylases DEN1/DenA and COP9 signalosome. PLoS Genet. 2013;9:e1003275 pubmed publisher
|
Zhou L, Luo H. Replication protein a links cell cycle progression and the onset of neurogenesis in Drosophila optic lobe development. J Neurosci. 2013;33:2873-88 pubmed publisher
|
Scotti E, Calamai M, Goulbourne C, Zhang L, Hong C, Lin R, et al. IDOL stimulates clathrin-independent endocytosis and multivesicular body-mediated lysosomal degradation of the low-density lipoprotein receptor. Mol Cell Biol. 2013;33:1503-14 pubmed publisher
|
Caldon C, Sergio C, Burgess A, Deans A, Sutherland R, Musgrove E. Cyclin E2 induces genomic instability by mechanisms distinct from cyclin E1. Cell Cycle. 2013;12:606-17 pubmed publisher
|
Dettmer U, Newman A, Luth E, Bartels T, Selkoe D. In vivo cross-linking reveals principally oligomeric forms of ?-synuclein and ?-synuclein in neurons and non-neural cells. J Biol Chem. 2013;288:6371-85 pubmed publisher
|
Kalyuga M, Gallego Ortega D, Lee H, Roden D, Cowley M, Caldon C, et al. ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. PLoS Biol. 2012;10:e1001461 pubmed publisher
|
Ver Heul A, Fowler C, Ramaswamy S, Piper R. Ubiquitin regulates caspase recruitment domain-mediated signaling by nucleotide-binding oligomerization domain-containing proteins NOD1 and NOD2. J Biol Chem. 2013;288:6890-902 pubmed publisher
|
Riva L, Thiry M, Bontems S, Joris A, Piette J, Lebrun M, et al. ORF9p phosphorylation by ORF47p is crucial for the formation and egress of varicella-zoster virus viral particles. J Virol. 2013;87:2868-81 pubmed publisher
|
Rannikko E, Vesterager L, Shaik J, Weber S, Cornejo Castro E, Fog K, et al. Loss of DJ-1 protein stability and cytoprotective function by Parkinson's disease-associated proline-158 deletion. J Neurochem. 2013;125:314-27 pubmed publisher
|
Pesti S, Balázs A, Udupa R, Szabo B, Fekete A, Bogel G, et al. Complex formation of EphB1/Nck/Caskin1 leads to tyrosine phosphorylation and structural changes of the Caskin1 SH3 domain. Cell Commun Signal. 2012;10:36 pubmed publisher
|
Arbab M, Mahony S, Cho H, Chick J, Rolfe P, van Hoff J, et al. A multi-parametric flow cytometric assay to analyze DNA-protein interactions. Nucleic Acids Res. 2013;41:e38 pubmed publisher
|
Saavedra Y, Day R, Seidah N. The M2 module of the Cys-His-rich domain (CHRD) of PCSK9 protein is needed for the extracellular low-density lipoprotein receptor (LDLR) degradation pathway. J Biol Chem. 2012;287:43492-501 pubmed publisher
|
Guan B, Gao M, Wu C, Wang T, Shih I. Functional analysis of in-frame indel ARID1A mutations reveals new regulatory mechanisms of its tumor suppressor functions. Neoplasia. 2012;14:986-93 pubmed
|
Song Y, Fang G, Shen H, Li H, Yang W, Pan B, et al. Human surfactant protein A2 gene mutations impair dimmer/trimer assembly leading to deficiency in protein sialylation and secretion. PLoS ONE. 2012;7:e46559 pubmed publisher
|
Nishioka C, Ikezoe T, Furihata M, Yang J, Serada S, Naka T, et al. CD34?/CD38? acute myelogenous leukemia cells aberrantly express CD82 which regulates adhesion and survival of leukemia stem cells. Int J Cancer. 2013;132:2006-19 pubmed publisher
|
Shao L, Tekedereli I, Wang J, Yuca E, Tsang S, Sood A, et al. Highly specific targeting of the TMPRSS2/ERG fusion gene using liposomal nanovectors. Clin Cancer Res. 2012;18:6648-57 pubmed publisher
|
Tuzer F, Madani N, Kamanna K, Zentner I, LaLonde J, Holmes A, et al. HIV-1 Env gp120 structural determinants for peptide triazole dual receptor site antagonism. Proteins. 2013;81:271-90 pubmed publisher
|
Giehl K, Eckstein G, Pasternack S, Praetzel Wunder S, Ruzicka T, Lichtner P, et al. Nonsense mutations in AAGAB cause punctate palmoplantar keratoderma type Buschke-Fischer-Brauer. Am J Hum Genet. 2012;91:754-9 pubmed publisher
|
Balaji K, Mooser C, Janson C, Bliss J, Hojjat H, Colicelli J. RIN1 orchestrates the activation of RAB5 GTPases and ABL tyrosine kinases to determine the fate of EGFR. J Cell Sci. 2012;125:5887-96 pubmed publisher
|
Sugimoto M, Sugimoto Y. Variant in the 5' untranslated region of insulin-like growth factor 1 receptor is associated with susceptibility to mastitis in cattle. G3 (Bethesda). 2012;2:1077-84 pubmed publisher
|
Shimizu K, Takahama S, Endo Y, Sawasaki T. Stress-inducible caspase substrate TRB3 promotes nuclear translocation of procaspase-3. PLoS ONE. 2012;7:e42721 pubmed publisher
|
Zhen A, Du J, Zhou X, Xiong Y, Yu X. Reduced APOBEC3H variant anti-viral activities are associated with altered RNA binding activities. PLoS ONE. 2012;7:e38771 pubmed publisher
|
Bogel G, Gujdár A, Geiszt M, Lanyi A, Fekete A, Sipeki S, et al. Frank-ter Haar syndrome protein Tks4 regulates epidermal growth factor-dependent cell migration. J Biol Chem. 2012;287:31321-9 pubmed publisher
|
Perez Mancera P, Rust A, van der Weyden L, Kristiansen G, Li A, Sarver A, et al. The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma. Nature. 2012;486:266-70 pubmed publisher
|
Yang J, O Donnell L, Durocher D, Brown G. RMI1 promotes DNA replication fork progression and recovery from replication fork stress. Mol Cell Biol. 2012;32:3054-64 pubmed publisher
|
Lee Y, Miller L, Chan X, Black M, Pang B, Ong C, et al. JMJD6 is a driver of cellular proliferation and motility and a marker of poor prognosis in breast cancer. Breast Cancer Res. 2012;14:R85 pubmed
|
Pruunsild P, Timmusk T. Subcellular localization and transcription regulatory potency of KCNIP/Calsenilin/DREAM/KChIP proteins in cultured primary cortical neurons do not provide support for their role in CRE-dependent gene expression. J Neurochem. 2012;123:29-43 pubmed publisher
|
Bentmann E, Neumann M, Tahirovic S, Rodde R, Dormann D, Haass C. Requirements for stress granule recruitment of fused in sarcoma (FUS) and TAR DNA-binding protein of 43 kDa (TDP-43). J Biol Chem. 2012;287:23079-94 pubmed publisher
|
Marazita M, Ogara M, Sonzogni S, Marti M, Dusetti N, Pignataro O, et al. CDK2 and PKA mediated-sequential phosphorylation is critical for p19INK4d function in the DNA damage response. PLoS ONE. 2012;7:e35638 pubmed publisher
|
Tan M, White E, Sowa M, Harper J, Aster J, Howley P. Cutaneous ?-human papillomavirus E6 proteins bind Mastermind-like coactivators and repress Notch signaling. Proc Natl Acad Sci U S A. 2012;109:E1473-80 pubmed publisher
|
Chhatriwala M, Cipolat S, Sevilla L, Nachat R, Watt F. Exons 5-15 of kazrin are dispensable for murine epidermal morphogenesis and homeostasis. J Invest Dermatol. 2012;132:1977-87 pubmed publisher
|
Harris G, Creason M, Brulte G, Herr D. In vitro and in vivo antagonism of a G protein-coupled receptor (S1P3) with a novel blocking monoclonal antibody. PLoS ONE. 2012;7:e35129 pubmed publisher
|
Nelersa C, Barreras H, Runko E, Ricard J, Shi Y, Glass S, et al. High-content analysis of proapoptotic EphA4 dependence receptor functions using small-molecule libraries. J Biomol Screen. 2012;17:785-95 pubmed publisher
|
Heldens L, van Genesen S, Hanssen L, Hageman J, Kampinga H, Lubsen N. Protein refolding in peroxisomes is dependent upon an HSF1-regulated function. Cell Stress Chaperones. 2012;17:603-13 pubmed publisher
|
Yu Z, Sato S, Trackman P, Kirsch K, Sonenshein G. Blimp1 activation by AP-1 in human lung cancer cells promotes a migratory phenotype and is inhibited by the lysyl oxidase propeptide. PLoS ONE. 2012;7:e33287 pubmed publisher
|
Oestreich K, Mohn S, Weinmann A. Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile. Nat Immunol. 2012;13:405-11 pubmed publisher
|
Grou C, Francisco T, Rodrigues T, Freitas M, Pinto M, Carvalho A, et al. Identification of ubiquitin-specific protease 9X (USP9X) as a deubiquitinase acting on ubiquitin-peroxin 5 (PEX5) thioester conjugate. J Biol Chem. 2012;287:12815-27 pubmed publisher
|
Uras I, List T, Nijman S. Ubiquitin-specific protease 4 inhibits mono-ubiquitination of the master growth factor signaling kinase PDK1. PLoS ONE. 2012;7:e31003 pubmed publisher
|
Gariano G, Dell Oste V, Bronzini M, Gatti D, Luganini A, de Andrea M, et al. The intracellular DNA sensor IFI16 gene acts as restriction factor for human cytomegalovirus replication. PLoS Pathog. 2012;8:e1002498 pubmed publisher
|
Ohnuki H, Inoue H, Takemori N, Nakayama H, Sakaue T, Fukuda S, et al. BAZF, a novel component of cullin3-based E3 ligase complex, mediates VEGFR and Notch cross-signaling in angiogenesis. Blood. 2012;119:2688-98 pubmed publisher
|
Rivera T, Ghenoiu C, Rodr guez Corsino M, Mochida S, Funabiki H, Losada A. Xenopus Shugoshin 2 regulates the spindle assembly pathway mediated by the chromosomal passenger complex. EMBO J. 2012;31:1467-79 pubmed publisher
|
Delgado Olguin P, Huang Y, Li X, Christodoulou D, Seidman C, Seidman J, et al. Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis. Nat Genet. 2012;44:343-7 pubmed publisher
|
Palmieri D, Valentino T, De Martino I, Esposito F, Cappabianca P, Wierinckx A, et al. PIT1 upregulation by HMGA proteins has a role in pituitary tumorigenesis. Endocr Relat Cancer. 2012;19:123-35 pubmed publisher
|
Addis R, Hsu F, Wright R, Dichter M, Coulter D, Gearhart J. Efficient conversion of astrocytes to functional midbrain dopaminergic neurons using a single polycistronic vector. PLoS ONE. 2011;6:e28719 pubmed publisher
|
Westerman B, Braat A, Taub N, Potman M, Vissers J, Blom M, et al. A genome-wide RNAi screen in mouse embryonic stem cells identifies Mp1 as a key mediator of differentiation. J Exp Med. 2011;208:2675-89 pubmed publisher
|
Han S, Bahmanyar S, Zhang P, Grishin N, Oegema K, Crooke R, et al. Nuclear envelope phosphatase 1-regulatory subunit 1 (formerly TMEM188) is the metazoan Spo7p ortholog and functions in the lipin activation pathway. J Biol Chem. 2012;287:3123-37 pubmed publisher
|
Alibhoy A, Giardina B, Dunton D, Chiang H. Vid30 is required for the association of Vid vesicles and actin patches in the vacuole import and degradation pathway. Autophagy. 2012;8:29-46 pubmed publisher
|
Kett L, Boassa D, Ho C, Rideout H, Hu J, Terada M, et al. LRRK2 Parkinson disease mutations enhance its microtubule association. Hum Mol Genet. 2012;21:890-9 pubmed publisher
|
Ahmed N, Zeng M, Sinha I, Polin L, Wei W, Rathinam C, et al. The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammation. Nat Immunol. 2011;12:1176-83 pubmed publisher
|
Léveillé N, Elkon R, Davalos V, Manoharan V, Hollingworth D, Oude Vrielink J, et al. Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity. Nat Commun. 2011;2:513 pubmed publisher
|
Yuan H, Rossetto D, Mellert H, Dang W, Srinivasan M, JOHNSON J, et al. MYST protein acetyltransferase activity requires active site lysine autoacetylation. EMBO J. 2012;31:58-70 pubmed publisher
|
Rapicavoli N, Poth E, Zhu H, Blackshaw S. The long noncoding RNA Six3OS acts in trans to regulate retinal development by modulating Six3 activity. Neural Dev. 2011;6:32 pubmed publisher
|
Taylor R, Lubick K, Robertson S, Broughton J, Bloom M, Bresnahan W, et al. TRIM79α, an interferon-stimulated gene product, restricts tick-borne encephalitis virus replication by degrading the viral RNA polymerase. Cell Host Microbe. 2011;10:185-96 pubmed publisher
|
Aksaas A, Larsen A, Rogne M, Rosendal K, Kvissel A, Skålhegg B. G-patch domain and KOW motifs-containing protein, GPKOW; a nuclear RNA-binding protein regulated by protein kinase A. J Mol Signal. 2011;6:10 pubmed publisher
|
An H, Shin H, Jo S, Kim Y, Lee J, Paik S, et al. The survival effect of mitochondrial Higd-1a is associated with suppression of cytochrome C release and prevention of caspase activation. Biochim Biophys Acta. 2011;1813:2088-98 pubmed publisher
|
Taylor R, Best S. Assessing ubiquitination of viral proteins: Lessons from flavivirus NS5. Methods. 2011;55:166-71 pubmed publisher
|
Ochiai K, Watanabe M, Ueki H, Huang P, Fujii Y, Nasu Y, et al. Tumor suppressor REIC/Dkk-3 interacts with the dynein light chain, Tctex-1. Biochem Biophys Res Commun. 2011;412:391-5 pubmed publisher
|
Kigel B, Rabinowicz N, Varshavsky A, Kessler O, Neufeld G. Plexin-A4 promotes tumor progression and tumor angiogenesis by enhancement of VEGF and bFGF signaling. Blood. 2011;118:4285-96 pubmed publisher
|
Ding L, Forsburg S. Schizosaccharomyces pombe minichromosome maintenance-binding protein (MCM-BP) antagonizes MCM helicase. J Biol Chem. 2011;286:32918-30 pubmed publisher
|
Cottam E, Maier H, Manifava M, Vaux L, Chandra Schoenfelder P, Gerner W, et al. Coronavirus nsp6 proteins generate autophagosomes from the endoplasmic reticulum via an omegasome intermediate. Autophagy. 2011;7:1335-47 pubmed publisher
|
Sánchez Morgan N, Kirsch K, Trackman P, Sonenshein G. The lysyl oxidase propeptide interacts with the receptor-type protein tyrosine phosphatase kappa and inhibits ?-catenin transcriptional activity in lung cancer cells. Mol Cell Biol. 2011;31:3286-97 pubmed publisher
|
Blanco F, Bernabeu C. Alternative splicing factor or splicing factor-2 plays a key role in intron retention of the endoglin gene during endothelial senescence. Aging Cell. 2011;10:896-907 pubmed publisher
|
Charvet C, Wissler M, Brauns Schubert P, Wang S, Tang Y, Sigloch F, et al. Phosphorylation of Tip60 by GSK-3 determines the induction of PUMA and apoptosis by p53. Mol Cell. 2011;42:584-96 pubmed publisher
|
Zhang Z, Norris J, Schwartz C, Alexov E. In silico and in vitro investigations of the mutability of disease-causing missense mutation sites in spermine synthase. PLoS ONE. 2011;6:e20373 pubmed publisher
|
Poliandri A, Gamsby J, Christian M, Spinella M, Loros J, Dunlap J, et al. Modulation of clock gene expression by the transcriptional coregulator receptor interacting protein 140 (RIP140). J Biol Rhythms. 2011;26:187-99 pubmed publisher
|
Yu W, Feng S, Dakhova O, Creighton C, Cai Y, Wang J, et al. FGFR-4 Arg³?? enhances prostate cancer progression via extracellular signal-related kinase and serum response factor signaling. Clin Cancer Res. 2011;17:4355-66 pubmed publisher
|
Yao T, Kim W, Yu D, Sharbeen G, McCaughan G, Choi K, et al. A novel role of dipeptidyl peptidase 9 in epidermal growth factor signaling. Mol Cancer Res. 2011;9:948-59 pubmed publisher
|
Li M, Hla T, Ferrer F. Sphingolipid modulation of angiogenic factor expression in neuroblastoma. Cancer Prev Res (Phila). 2011;4:1325-32 pubmed publisher
|
Sato S, Trackman P, Maki J, Myllyharju J, Kirsch K, Sonenshein G. The Ras signaling inhibitor LOX-PP interacts with Hsp70 and c-Raf to reduce Erk activation and transformed phenotype of breast cancer cells. Mol Cell Biol. 2011;31:2683-95 pubmed publisher
|
Laederich M, Degnin C, Lunstrum G, Holden P, Horton W. Fibroblast growth factor receptor 3 (FGFR3) is a strong heat shock protein 90 (Hsp90) client: implications for therapeutic manipulation. J Biol Chem. 2011;286:19597-604 pubmed publisher
|
Rakovic A, Grünewald A, Kottwitz J, Brüggemann N, Pramstaller P, Lohmann K, et al. Mutations in PINK1 and Parkin impair ubiquitination of Mitofusins in human fibroblasts. PLoS ONE. 2011;6:e16746 pubmed publisher
|
Zhang S, Xia Y, Kim B, Keyhani N. Two hydrophobins are involved in fungal spore coat rodlet layer assembly and each play distinct roles in surface interactions, development and pathogenesis in the entomopathogenic fungus, Beauveria bassiana. Mol Microbiol. 2011;80:811-26 pubmed publisher
|
Pruunsild P, Sepp M, Orav E, Koppel I, Timmusk T. Identification of cis-elements and transcription factors regulating neuronal activity-dependent transcription of human BDNF gene. J Neurosci. 2011;31:3295-308 pubmed publisher
|
Fuhs S, Insel P. Caveolin-3 undergoes SUMOylation by the SUMO E3 ligase PIASy: sumoylation affects G-protein-coupled receptor desensitization. J Biol Chem. 2011;286:14830-41 pubmed publisher
|
Chen X, Zhang H, Aravindakshan J, Gotlieb W, Sairam M. Anti-proliferative and pro-apoptotic actions of a novel human and mouse ovarian tumor-associated gene OTAG-12: downregulation, alternative splicing and drug sensitization. Oncogene. 2011;30:2874-87 pubmed publisher
|
Finkbeiner E, Haindl M, Muller S. The SUMO system controls nucleolar partitioning of a novel mammalian ribosome biogenesis complex. EMBO J. 2011;30:1067-78 pubmed publisher
|
Stulemeijer I, Pike B, Faber A, Verzijlbergen K, van Welsem T, Frederiks F, et al. Dot1 binding induces chromatin rearrangements by histone methylation-dependent and -independent mechanisms. Epigenetics Chromatin. 2011;4:2 pubmed publisher
|
Ding Z, Wu C, Chu G, Xiao Y, Ho D, Zhang J, et al. SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression. Nature. 2011;470:269-73 pubmed publisher
|
Nawaz M, Merriman E, Yang X, Schimmel P. p23H implicated as cis/trans regulator of AlaXp-directed editing for mammalian cell homeostasis. Proc Natl Acad Sci U S A. 2011;108:2723-8 pubmed publisher
|
Lu W, Lee N, Kaul S, Lan F, Poon R, Wadhwa R, et al. Mortalin-p53 interaction in cancer cells is stress dependent and constitutes a selective target for cancer therapy. Cell Death Differ. 2011;18:1046-56 pubmed publisher
|
Waschk D, Fabian A, Budde T, Schwab A. Dual-color quantum dot detection of a heterotetrameric potassium channel (hKCa3.1). Am J Physiol Cell Physiol. 2011;300:C843-9 pubmed publisher
|
Boonyaratanakornkit J, Bartlett E, Schomacker H, Surman S, Akira S, Bae Y, et al. The C proteins of human parainfluenza virus type 1 limit double-stranded RNA accumulation that would otherwise trigger activation of MDA5 and protein kinase R. J Virol. 2011;85:1495-506 pubmed publisher
|
Cervenka I, Wolf J, Masek J, Krejci P, Wilcox W, Kozubik A, et al. Mitogen-activated protein kinases promote WNT/beta-catenin signaling via phosphorylation of LRP6. Mol Cell Biol. 2011;31:179-89 pubmed publisher
|
Hewer R, Sala Newby G, Wu Y, Newby A, Bond M. PKA and Epac synergistically inhibit smooth muscle cell proliferation. J Mol Cell Cardiol. 2011;50:87-98 pubmed publisher
|
Zhang W, Du J, Yu K, Wang T, Yong X, Yu X. Association of potent human antiviral cytidine deaminases with 7SL RNA and viral RNP in HIV-1 virions. J Virol. 2010;84:12903-13 pubmed publisher
|
Li Y, Cao H, Jiao Z, Pakala S, Sirigiri D, Li W, et al. Carcinoembryonic antigen interacts with TGF-{beta} receptor and inhibits TGF-{beta} signaling in colorectal cancers. Cancer Res. 2010;70:8159-68 pubmed publisher
|
Kuny C, Chinchilla K, Culbertson M, Kalejta R. Cyclin-dependent kinase-like function is shared by the beta- and gamma- subset of the conserved herpesvirus protein kinases. PLoS Pathog. 2010;6:e1001092 pubmed publisher
|
Schjoldager K, Vester Christensen M, Bennett E, Levery S, Schwientek T, Yin W, et al. O-glycosylation modulates proprotein convertase activation of angiopoietin-like protein 3: possible role of polypeptide GalNAc-transferase-2 in regulation of concentrations of plasma lipids. J Biol Chem. 2010;285:36293-303 pubmed publisher
|
Tower C, Fu L, Gill R, Prichard M, Lesort M, Sztul E. Human cytomegalovirus UL97 kinase prevents the deposition of mutant protein aggregates in cellular models of Huntington's disease and ataxia. Neurobiol Dis. 2011;41:11-22 pubmed publisher
|
Huang X, Morse L, Xu Y, Zahradka J, Sychrova H, Stashenko P, et al. Mutational analysis of NHAoc/NHA2 in Saccharomyces cerevisiae. Biochim Biophys Acta. 2010;1800:1241-7 pubmed publisher
|
Perocchi F, Gohil V, Girgis H, Bao X, McCombs J, Palmer A, et al. MICU1 encodes a mitochondrial EF hand protein required for Ca(2+) uptake. Nature. 2010;467:291-6 pubmed publisher
|
Heldens L, Dirks R, Hensen S, Onnekink C, van Genesen S, Rustenburg F, et al. Co-chaperones are limiting in a depleted chaperone network. Cell Mol Life Sci. 2010;67:4035-48 pubmed publisher
|
Maitra M, Wang Y, Gerard R, Mendelson C, Garcia C. Surfactant protein A2 mutations associated with pulmonary fibrosis lead to protein instability and endoplasmic reticulum stress. J Biol Chem. 2010;285:22103-13 pubmed publisher
|
Song G, Kim H, Woo K, Baek J, Kim G, Choi J, et al. Molecular consequences of the ACVR1(R206H) mutation of fibrodysplasia ossificans progressiva. J Biol Chem. 2010;285:22542-53 pubmed publisher
|
Fusco D, Vargiolu M, Vidone M, Mariani E, Pennisi L, Bonora E, et al. The RET51/FKBP52 complex and its involvement in Parkinson disease. Hum Mol Genet. 2010;19:2804-16 pubmed publisher
|
Katsuno M, Adachi H, Minamiyama M, Waza M, Doi H, Kondo N, et al. Disrupted transforming growth factor-beta signaling in spinal and bulbar muscular atrophy. J Neurosci. 2010;30:5702-12 pubmed publisher
|
Patterson K, Brummer T, Daly R, O Brien P. DUSP26 negatively affects the proliferation of epithelial cells, an effect not mediated by dephosphorylation of MAPKs. Biochim Biophys Acta. 2010;1803:1003-12 pubmed publisher
|
Kuhr F, Zhang Y, Brovkovych V, Skidgel R. Beta-arrestin 2 is required for B1 receptor-dependent post-translational activation of inducible nitric oxide synthase. FASEB J. 2010;24:2475-83 pubmed publisher
|
Masuda M, Maruyama T, Ohta T, Ito A, Hayashi T, Tsukasaki K, et al. CADM1 interacts with Tiam1 and promotes invasive phenotype of human T-cell leukemia virus type I-transformed cells and adult T-cell leukemia cells. J Biol Chem. 2010;285:15511-22 pubmed publisher
|
Yamanaka T, Tosaki A, Miyazaki H, Kurosawa M, Furukawa Y, Yamada M, et al. Mutant huntingtin fragment selectively suppresses Brn-2 POU domain transcription factor to mediate hypothalamic cell dysfunction. Hum Mol Genet. 2010;19:2099-112 pubmed publisher
|
Däubner T, Fink A, Seitz A, Tenzer S, Müller J, Strand D, et al. A novel transmembrane domain mediating retention of a highly motile herpesvirus glycoprotein in the endoplasmic reticulum. J Gen Virol. 2010;91:1524-34 pubmed publisher
|
He S, McPhaul C, Li J, Garuti R, Kinch L, Grishin N, et al. A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis. J Biol Chem. 2010;285:6706-15 pubmed publisher
|
Fan L, Briese T, Lipkin W. Z proteins of New World arenaviruses bind RIG-I and interfere with type I interferon induction. J Virol. 2010;84:1785-91 pubmed publisher
|
Holden P, Horton W. Crude subcellular fractionation of cultured mammalian cell lines. BMC Res Notes. 2009;2:243 pubmed publisher
|
Zhen A, Wang T, Zhao K, Xiong Y, Yu X. A single amino acid difference in human APOBEC3H variants determines HIV-1 Vif sensitivity. J Virol. 2010;84:1902-11 pubmed publisher
|
Robinson J, Vanbrocklin M, Guilbeault A, Signorelli D, Brandner S, Holmen S. Activated BRAF induces gliomas in mice when combined with Ink4a/Arf loss or Akt activation. Oncogene. 2010;29:335-44 pubmed publisher
|
Sekimata M, Pérez Melgosa M, Miller S, Weinmann A, Sabo P, Sandstrom R, et al. CCCTC-binding factor and the transcription factor T-bet orchestrate T helper 1 cell-specific structure and function at the interferon-gamma locus. Immunity. 2009;31:551-64 pubmed publisher
|
Wang L, Liu R, Li W, Chen C, Katoh H, Chen G, et al. Somatic single hits inactivate the X-linked tumor suppressor FOXP3 in the prostate. Cancer Cell. 2009;16:336-46 pubmed publisher
|
O Farrell C, Martin K, Hutton M, Delatycki M, Cookson M, Lockhart P. Mutant torsinA interacts with tyrosine hydroxylase in cultured cells. Neuroscience. 2009;164:1127-37 pubmed publisher
|
Jin Q, Gao G, Mulder K. Requirement of a dynein light chain in TGFbeta/Smad3 signaling. J Cell Physiol. 2009;221:707-15 pubmed publisher
|
Skube S, Chaverri J, Goodson H. Effect of GFP tags on the localization of EB1 and EB1 fragments in vivo. Cytoskeleton (Hoboken). 2010;67:1-12 pubmed publisher
|
Schwartz V, Lue H, Kraemer S, Korbiel J, Krohn R, Ohl K, et al. A functional heteromeric MIF receptor formed by CD74 and CXCR4. FEBS Lett. 2009;583:2749-57 pubmed publisher
|
Campeau E, Ruhl V, Rodier F, Smith C, Rahmberg B, FUSS J, et al. A versatile viral system for expression and depletion of proteins in mammalian cells. PLoS ONE. 2009;4:e6529 pubmed publisher
|
Chen G, He Z, Wang T, Xu R, Yu X. A patch of positively charged amino acids surrounding the human immunodeficiency virus type 1 Vif SLVx4Yx9Y motif influences its interaction with APOBEC3G. J Virol. 2009;83:8674-82 pubmed publisher
|
Wong J, Weickert C. Transcriptional interaction of an estrogen receptor splice variant and ErbB4 suggests convergence in gene susceptibility pathways in schizophrenia. J Biol Chem. 2009;284:18824-32 pubmed publisher
|
Etchegaray J, Machida K, Noton E, Constance C, Dallmann R, Di Napoli M, et al. Casein kinase 1 delta regulates the pace of the mammalian circadian clock. Mol Cell Biol. 2009;29:3853-66 pubmed publisher
|
Li S, Yen T, Endo Y, Klauzinska M, Baljinnyam B, Macher B, et al. Loss-of-function point mutations and two-furin domain derivatives provide insights about R-spondin2 structure and function. Cell Signal. 2009;21:916-25 pubmed
|
Wörter V, Schweigreiter R, Kinzel B, Mueller M, Barske C, Böck G, et al. Inhibitory activity of myelin-associated glycoprotein on sensory neurons is largely independent of NgR1 and NgR2 and resides within Ig-Like domains 4 and 5. PLoS ONE. 2009;4:e5218 pubmed publisher
|
Schmuckli Maurer J, Casanova C, Schmied S, Affentranger S, Parvanova I, Kang a S, et al. Expression analysis of the Theileria parva subtelomere-encoded variable secreted protein gene family. PLoS ONE. 2009;4:e4839 pubmed publisher
|
Lee S, Ou D, Lee C, Juan L. Gene-specific transcriptional activation mediated by the p150 subunit of the chromatin assembly factor 1. J Biol Chem. 2009;284:14040-9 pubmed publisher
|
Rambaud J, Desroches J, Balsalobre A, Drouin J. TIF1beta/KAP-1 is a coactivator of the orphan nuclear receptor NGFI-B/Nur77. J Biol Chem. 2009;284:14147-56 pubmed publisher
|
Jinawath N, Vasoontara C, Yap K, Thiaville M, Nakayama K, Wang T, et al. NAC-1, a potential stem cell pluripotency factor, contributes to paclitaxel resistance in ovarian cancer through inactivating Gadd45 pathway. Oncogene. 2009;28:1941-8 pubmed publisher
|
Maier B, Wendt S, Vanselow J, Wallach T, Reischl S, Oehmke S, et al. A large-scale functional RNAi screen reveals a role for CK2 in the mammalian circadian clock. Genes Dev. 2009;23:708-18 pubmed publisher
|
Reindl C, Quentmeier H, Petropoulos K, Greif P, Benthaus T, Argiropoulos B, et al. CBL exon 8/9 mutants activate the FLT3 pathway and cluster in core binding factor/11q deletion acute myeloid leukemia/myelodysplastic syndrome subtypes. Clin Cancer Res. 2009;15:2238-47 pubmed publisher
|
Dasgupta A, Raychaudhuri B, Haqqi T, Prayson R, Van Meir E, Vogelbaum M, et al. Stat3 activation is required for the growth of U87 cell-derived tumours in mice. Eur J Cancer. 2009;45:677-84 pubmed publisher
|
Mungrue I, Pagnon J, Kohannim O, Gargalovic P, Lusis A. CHAC1/MGC4504 is a novel proapoptotic component of the unfolded protein response, downstream of the ATF4-ATF3-CHOP cascade. J Immunol. 2009;182:466-76 pubmed
|
Wang Y, Kuan P, Xing C, Cronkhite J, Torres F, Rosenblatt R, et al. Genetic defects in surfactant protein A2 are associated with pulmonary fibrosis and lung cancer. Am J Hum Genet. 2009;84:52-9 pubmed publisher
|
Zhang W, Chen G, Niewiadomska A, Xu R, Yu X. Distinct determinants in HIV-1 Vif and human APOBEC3 proteins are required for the suppression of diverse host anti-viral proteins. PLoS ONE. 2008;3:e3963 pubmed publisher
|
Lee S, Bahn J, Choi C, Whitlock N, English A, Safe S, et al. ESE-1/EGR-1 pathway plays a role in tolfenamic acid-induced apoptosis in colorectal cancer cells. Mol Cancer Ther. 2008;7:3739-50 pubmed publisher
|
Miller S, Huang A, Miazgowicz M, Brassil M, Weinmann A. Coordinated but physically separable interaction with H3K27-demethylase and H3K4-methyltransferase activities are required for T-box protein-mediated activation of developmental gene expression. Genes Dev. 2008;22:2980-93 pubmed publisher
|
Bao X, Cai W, Deng H, Zhang W, Krencik R, Girton J, et al. The COOH-terminal domain of the JIL-1 histone H3S10 kinase interacts with histone H3 and is required for correct targeting to chromatin. J Biol Chem. 2008;283:32741-50 pubmed publisher
|
Lim Y, McLaughlin T, Sung T, Santiago A, Lee K, O Leary D. p75(NTR) mediates ephrin-A reverse signaling required for axon repulsion and mapping. Neuron. 2008;59:746-58 pubmed publisher
|
Li Y, Xu W, McBurney M, Longo V. SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons. Cell Metab. 2008;8:38-48 pubmed publisher
|
Caldon C, Swarbrick A, Lee C, Sutherland R, Musgrove E. The helix-loop-helix protein Id1 requires cyclin D1 to promote the proliferation of mammary epithelial cell acini. Cancer Res. 2008;68:3026-36 pubmed publisher
|
Chandramohan V, Mineva N, Burke B, Jeay S, Wu M, Shen J, et al. c-Myc represses FOXO3a-mediated transcription of the gene encoding the p27(Kip1) cyclin dependent kinase inhibitor. J Cell Biochem. 2008;104:2091-106 pubmed publisher
|
Yamanaka T, Miyazaki H, Oyama F, Kurosawa M, Washizu C, Doi H, et al. Mutant Huntingtin reduces HSP70 expression through the sequestration of NF-Y transcription factor. EMBO J. 2008;27:827-39 pubmed publisher
|
Battaglino R, Pham L, Morse L, Vokes M, Sharma A, Odgren P, et al. NHA-oc/NHA2: a mitochondrial cation-proton antiporter selectively expressed in osteoclasts. Bone. 2008;42:180-92 pubmed
|
Haberkant P, Schmitt O, Contreras F, Thiele C, Hanada K, Sprong H, et al. Protein-sphingolipid interactions within cellular membranes. J Lipid Res. 2008;49:251-62 pubmed
|
Nitta R, Smith C, Kennedy B. Evidence that proteasome-dependent degradation of the retinoblastoma protein in cells lacking A-type lamins occurs independently of gankyrin and MDM2. PLoS ONE. 2007;2:e963 pubmed
|
Golks A, Tran T, Goetschy J, Guerini D. Requirement for O-linked N-acetylglucosaminyltransferase in lymphocytes activation. EMBO J. 2007;26:4368-79 pubmed
|
McLaughlin B, Chon J, MacGurn J, Carlsson F, Cheng T, Cox J, et al. A mycobacterium ESX-1-secreted virulence factor with unique requirements for export. PLoS Pathog. 2007;3:e105 pubmed
|
Ursini Siegel J, Rajput A, Lu H, Sanguin Gendreau V, Zuo D, Papavasiliou V, et al. Elevated expression of DecR1 impairs ErbB2/Neu-induced mammary tumor development. Mol Cell Biol. 2007;27:6361-71 pubmed
|
Nachury M, Loktev A, Zhang Q, Westlake C, Peranen J, Merdes A, et al. A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis. Cell. 2007;129:1201-13 pubmed
|
Driskell R, Goodheart M, Neff T, Liu X, Luo M, Moothart C, et al. Wnt3a regulates Lef-1 expression during airway submucosal gland morphogenesis. Dev Biol. 2007;305:90-102 pubmed
|
Chan W, Poon R. The p53 Isoform Deltap53 lacks intrinsic transcriptional activity and reveals the critical role of nuclear import in dominant-negative activity. Cancer Res. 2007;67:1959-69 pubmed
|
Weaver I, D Alessio A, Brown S, Hellstrom I, Dymov S, Sharma S, et al. The transcription factor nerve growth factor-inducible protein a mediates epigenetic programming: altering epigenetic marks by immediate-early genes. J Neurosci. 2007;27:1756-68 pubmed
|
Hao L, ElShamy W. BRCA1-IRIS activates cyclin D1 expression in breast cancer cells by downregulating the JNK phosphatase DUSP3/VHR. Int J Cancer. 2007;121:39-46 pubmed
|
Morgan K, Rowley M, Wiesner S, Hasz D, Van Ness B, Largaespada D. The GAP-related domain of neurofibromin attenuates proliferation and downregulates N- and K-Ras activation in Nf1-negative AML cells. Leuk Res. 2007;31:1107-13 pubmed
|
Hock T, Liby K, Wright M, McConnell S, Schorpp Kistner M, Ryan T, et al. JunB and JunD regulate human heme oxygenase-1 gene expression in renal epithelial cells. J Biol Chem. 2007;282:6875-86 pubmed
|
Barfod L, Bernasconi N, Dahlbäck M, Jarrossay D, Andersen P, Salanti A, et al. Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA. Mol Microbiol. 2007;63:335-47 pubmed
|
Dahlbäck M, Rask T, Andersen P, Nielsen M, Ndam N, Resende M, et al. Epitope mapping and topographic analysis of VAR2CSA DBL3X involved in P. falciparum placental sequestration. PLoS Pathog. 2006;2:e124 pubmed
|
Illman S, Lehti K, Keski Oja J, Lohi J. Epilysin (MMP-28) induces TGF-beta mediated epithelial to mesenchymal transition in lung carcinoma cells. J Cell Sci. 2006;119:3856-65 pubmed
|
Ivanova I, Dagnino L. Activation of p38- and CRM1-dependent nuclear export promotes E2F1 degradation during keratinocyte differentiation. Oncogene. 2007;26:1147-54 pubmed
|
Kim J, Yang C, Stallcup M. Downstream signaling mechanism of the C-terminal activation domain of transcriptional coactivator CoCoA. Nucleic Acids Res. 2006;34:2736-50 pubmed
|
Yan H, Cheng C. Laminin alpha 3 forms a complex with beta3 and gamma3 chains that serves as the ligand for alpha 6beta1-integrin at the apical ectoplasmic specialization in adult rat testes. J Biol Chem. 2006;281:17286-303 pubmed
|
Hamada S, Satoh K, Kimura K, Kanno A, Masamune A, Shimosegawa T. MSX2 overexpression inhibits gemcitabine-induced caspase-3 activity in pancreatic cancer cells. World J Gastroenterol. 2005;11:6867-70 pubmed
|
Lu J, Piazza T, Schuler L. Proteasomes mediate prolactin-induced receptor down-regulation and fragment generation in breast cancer cells. J Biol Chem. 2005;280:33909-16 pubmed
|
Polgar D, Leisser C, Maier S, Strasser S, Rüger B, Dettke M, et al. Truncated ALK derived from chromosomal translocation t(2;5)(p23;q35) binds to the SH3 domain of p85-PI3K. Mutat Res. 2005;570:9-15 pubmed
|
Kim J, Stallcup M. Role of the coiled-coil coactivator (CoCoA) in aryl hydrocarbon receptor-mediated transcription. J Biol Chem. 2004;279:49842-8 pubmed
|
Powell D, Weaver C, Jennings J, McAfee K, He Y, Weil P, et al. Cluster analysis of mass spectrometry data reveals a novel component of SAGA. Mol Cell Biol. 2004;24:7249-59 pubmed
|
Mak S, Kültz D. Gadd45 proteins induce G2/M arrest and modulate apoptosis in kidney cells exposed to hyperosmotic stress. J Biol Chem. 2004;279:39075-84 pubmed
|
Hu X, Yagi Y, Tanji T, Zhou S, Ip Y. Multimerization and interaction of Toll and Spätzle in Drosophila. Proc Natl Acad Sci U S A. 2004;101:9369-74 pubmed
|
Grabar T, Cain B. Genetic complementation between mutant b subunits in F1F0 ATP synthase. J Biol Chem. 2004;279:31205-11 pubmed
|
Hewett J, Kamm C, Boston H, Beauchamp R, Naismith T, Ozelius L, et al. TorsinB--perinuclear location and association with torsinA. J Neurochem. 2004;89:1186-94 pubmed
|
Huitema K, van den Dikkenberg J, Brouwers J, Holthuis J. Identification of a family of animal sphingomyelin synthases. EMBO J. 2004;23:33-44 pubmed
|
Maeda O, Usami N, Kondo M, Takahashi M, Goto H, Shimokata K, et al. Plakoglobin (gamma-catenin) has TCF/LEF family-dependent transcriptional activity in beta-catenin-deficient cell line. Oncogene. 2004;23:964-72 pubmed
|
Rao K, He Y, Kalyanasundaram R. Expression of a 28-kilodalton glutathione S-transferase antigen of Schistosoma mansoni on the surface of filamentous phages and evaluation of its vaccine potential. Clin Diagn Lab Immunol. 2003;10:536-41 pubmed
|
Ito T, Niwa J, Hishikawa N, Ishigaki S, Doyu M, Sobue G. Dorfin localizes to Lewy bodies and ubiquitylates synphilin-1. J Biol Chem. 2003;278:29106-14 pubmed
|
Wu C, Wu F, Pan J, Morser J, Wu Q. Furin-mediated processing of Pro-C-type natriuretic peptide. J Biol Chem. 2003;278:25847-52 pubmed
|
Place R, Haspeslagh D, Giardina C. Induced stabilization of IkappaBalpha can facilitate its re-synthesis and prevent sequential degradation. J Cell Physiol. 2003;195:470-8 pubmed
|
Danilkovitch Miagkova A, Duh F, Kuzmin I, Angeloni D, Liu S, Miller A, et al. Hyaluronidase 2 negatively regulates RON receptor tyrosine kinase and mediates transformation of epithelial cells by jaagsiekte sheep retrovirus. Proc Natl Acad Sci U S A. 2003;100:4580-5 pubmed
|
Vespa A, Darmon A, Turner C, D Souza S, Dagnino L. Ca2+-dependent localization of integrin-linked kinase to cell junctions in differentiating keratinocytes. J Biol Chem. 2003;278:11528-35 pubmed
|
Tang Q, Staub C, Gao G, Jin Q, Wang Z, Ding W, et al. A novel transforming growth factor-beta receptor-interacting protein that is also a light chain of the motor protein dynein. Mol Biol Cell. 2002;13:4484-96 pubmed
|
Sasaki Y, Cheng C, Uchida Y, Nakajima O, Ohshima T, Yagi T, et al. Fyn and Cdk5 mediate semaphorin-3A signaling, which is involved in regulation of dendrite orientation in cerebral cortex. Neuron. 2002;35:907-20 pubmed
|
Langley B, Thomas M, Bishop A, Sharma M, Gilmour S, Kambadur R. Myostatin inhibits myoblast differentiation by down-regulating MyoD expression. J Biol Chem. 2002;277:49831-40 pubmed
|
Blagoev B, Kratchmarova I, Nielsen M, Fernandez M, Voldby J, Andersen J, et al. Inhibition of adipocyte differentiation by resistin-like molecule alpha. Biochemical characterization of its oligomeric nature. J Biol Chem. 2002;277:42011-6 pubmed
|
Cavarec L, Kamphausen T, Dubourg B, Callebaut I, Lemeunier F, Metivier D, et al. Identification and characterization of Moca-cyp. A Drosophila melanogaster nuclear cyclophilin. J Biol Chem. 2002;277:41171-82 pubmed
|
Zhang Y, Dufau M. Silencing of transcription of the human luteinizing hormone receptor gene by histone deacetylase-mSin3A complex. J Biol Chem. 2002;277:33431-8 pubmed
|
Perelygin A, Scherbik S, Zhulin I, Stockman B, Li Y, Brinton M. Positional cloning of the murine flavivirus resistance gene. Proc Natl Acad Sci U S A. 2002;99:9322-7 pubmed
|
Reeve I, Hummel D, Nelson N, Voss J, Hummell D. Overexpression, purification, and site-directed spin labeling of the Nramp metal transporter from Mycobacterium leprae. Proc Natl Acad Sci U S A. 2002;99:8608-13 pubmed
|
Vainauskas S, Maeda Y, Kurniawan H, Kinoshita T, Menon A. Structural requirements for the recruitment of Gaa1 into a functional glycosylphosphatidylinositol transamidase complex. J Biol Chem. 2002;277:30535-42 pubmed
|
Chen Y, Cai J, Murphy T, Jones D. Overexpressed human mitochondrial thioredoxin confers resistance to oxidant-induced apoptosis in human osteosarcoma cells. J Biol Chem. 2002;277:33242-8 pubmed
|
Scott M, Zappacosta F, Kim E, Annan R, Miller W. Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1. J Biol Chem. 2002;277:28238-46 pubmed
|
Stacey M, Chang G, Sanos S, Chittenden L, Stubbs L, Gordon S, et al. EMR4, a novel epidermal growth factor (EGF)-TM7 molecule up-regulated in activated mouse macrophages, binds to a putative cellular ligand on B lymphoma cell line A20. J Biol Chem. 2002;277:29283-93 pubmed
|
Cavanaugh A, Hirschler Laszkiewicz I, Hu Q, Dundr M, Smink T, Misteli T, et al. Rrn3 phosphorylation is a regulatory checkpoint for ribosome biogenesis. J Biol Chem. 2002;277:27423-32 pubmed
|
Conti L, Radeke C, Vandenberg C. Membrane targeting of ATP-sensitive potassium channel. Effects of glycosylation on surface expression. J Biol Chem. 2002;277:25416-22 pubmed
|
Yang Y, Li L, Wong G, Krilis S, Madhusudhan M, Sali A, et al. RasGRP4, a new mast cell-restricted Ras guanine nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs. Identification of defective variants of this signaling protein in asthma, mastocytosis, and mast cell leukemia patients and . J Biol Chem. 2002;277:25756-74 pubmed
|
Trivier E, Ganesan T. RYK, a catalytically inactive receptor tyrosine kinase, associates with EphB2 and EphB3 but does not interact with AF-6. J Biol Chem. 2002;277:23037-43 pubmed
|
Bennin D, Don A, Brake T, McKenzie J, Rosenbaum H, Ortiz L, et al. Cyclin G2 associates with protein phosphatase 2A catalytic and regulatory B' subunits in active complexes and induces nuclear aberrations and a G1/S phase cell cycle arrest. J Biol Chem. 2002;277:27449-67 pubmed
|
Vulin A, Stanley F. A Forkhead/winged helix-related transcription factor mediates insulin-increased plasminogen activator inhibitor-1 gene transcription. J Biol Chem. 2002;277:20169-76 pubmed
|
Kumar A, Agarwal S, Heyman J, Matson S, Heidtman M, Piccirillo S, et al. Subcellular localization of the yeast proteome. Genes Dev. 2002;16:707-19 pubmed
|
Wu F, Yan W, Pan J, Morser J, Wu Q. Processing of pro-atrial natriuretic peptide by corin in cardiac myocytes. J Biol Chem. 2002;277:16900-5 pubmed
|
Xie Z, Ho W, Spellman R, Cai S, Exton J. Mechanisms of regulation of phospholipase D1 and D2 by the heterotrimeric G proteins G13 and Gq. J Biol Chem. 2002;277:11979-86 pubmed
|
Segade F, Trask B, Broekelmann T, Pierce R, Mecham R. Identification of a matrix-binding domain in MAGP1 and MAGP2 and intracellular localization of alternative splice forms. J Biol Chem. 2002;277:11050-7 pubmed
|
Leboulle G, Crippa M, Decrem Y, Mejri N, Brossard M, Bollen A, et al. Characterization of a novel salivary immunosuppressive protein from Ixodes ricinus ticks. J Biol Chem. 2002;277:10083-9 pubmed
|
Malakhov M, Malakhova O, Kim K, Ritchie K, Zhang D. UBP43 (USP18) specifically removes ISG15 from conjugated proteins. J Biol Chem. 2002;277:9976-81 pubmed
|
Elagoz A, Benjannet S, Mammarbassi A, Wickham L, Seidah N. Biosynthesis and cellular trafficking of the convertase SKI-1/S1P: ectodomain shedding requires SKI-1 activity. J Biol Chem. 2002;277:11265-75 pubmed
|
Vargas L, Nore B, Berglof A, Heinonen J, Mattsson P, Smith C, et al. Functional interaction of caveolin-1 with Bruton's tyrosine kinase and Bmx. J Biol Chem. 2002;277:9351-7 pubmed
|
Tan C, Mui A, Dedhar S. Integrin-linked kinase regulates inducible nitric oxide synthase and cyclooxygenase-2 expression in an NF-kappa B-dependent manner. J Biol Chem. 2002;277:3109-16 pubmed
|
Gubitz A, Mourelatos Z, Abel L, Rappsilber J, Mann M, Dreyfuss G. Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins. J Biol Chem. 2002;277:5631-6 pubmed
|
Wang H, Kazanietz M. Chimaerins, novel non-protein kinase C phorbol ester receptors, associate with Tmp21-I (p23): evidence for a novel anchoring mechanism involving the chimaerin C1 domain. J Biol Chem. 2002;277:4541-50 pubmed
|
Horng T, Medzhitov R. Drosophila MyD88 is an adapter in the Toll signaling pathway. Proc Natl Acad Sci U S A. 2001;98:12654-8 pubmed
|
Dreger M, Bengtsson L, Schoneberg T, Otto H, Hucho F. Nuclear envelope proteomics: novel integral membrane proteins of the inner nuclear membrane. Proc Natl Acad Sci U S A. 2001;98:11943-8 pubmed
|
Furge K, Kiewlich D, Le P, Vo M, Faure M, Howlett A, et al. Suppression of Ras-mediated tumorigenicity and metastasis through inhibition of the Met receptor tyrosine kinase. Proc Natl Acad Sci U S A. 2001;98:10722-7 pubmed
|
Kaminker P, Kim S, Taylor R, Zebarjadian Y, Funk W, Morin G, et al. TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression. J Biol Chem. 2001;276:35891-9 pubmed
|
Jackson M, Lindstrom M, Berberich S. MdmX binding to ARF affects Mdm2 protein stability and p53 transactivation. J Biol Chem. 2001;276:25336-41 pubmed
|
Dai K, Liew C. A novel human striated muscle RING zinc finger protein, SMRZ, interacts with SMT3b via its RING domain. J Biol Chem. 2001;276:23992-9 pubmed
|
Yan W, Wu F, Morser J, Wu Q. Corin, a transmembrane cardiac serine protease, acts as a pro-atrial natriuretic peptide-converting enzyme. Proc Natl Acad Sci U S A. 2000;97:8525-9 pubmed
|
Lee J, Collins K, Brown A, Lee C, Chung J. hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response. Nature. 2000;404:201-4 pubmed
|
Herrmann B, Koschorz B, Wertz K, Mclaughlin K, Kispert A. A protein kinase encoded by the t complex responder gene causes non-mendelian inheritance. Nature. 1999;402:141-6 pubmed
|
Wilson W, Mahrenholz A, Roach P. Substrate targeting of the yeast cyclin-dependent kinase Pho85p by the cyclin Pcl10p. Mol Cell Biol. 1999;19:7020-30 pubmed
|