CD4 Monoclonal Antibody (RM4-5), Qdot™ 605 | Invitrogen Q10092 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD4 Monoclonal Antibody (RM4-5), Qdot™ 605

catalog :

Q10092

quantity :

100 µL

price :

US 562.00

clonality :

monoclonal

host :

rat

conjugate :

Qdot 605

clone name :

RM4-5

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; fig 6	Navarathna D, Stein E, Lessey Morillon E, Nayak D, Martin Manso G, Roberts D. CD47 Promotes Protective Innate and Adaptive Immunity in a Mouse Model of Disseminated Candidiasis. PLoS ONE. 2015;10:e0128220 pubmed publisher
flow cytometry; mouse; fig 2	Au Yeung B, Melichar H, Ross J, Cheng D, Zikherman J, Shokat K, et al. Quantitative and temporal requirements revealed for Zap70 catalytic activity during T cell development. Nat Immunol. 2014;15:687-94 pubmed publisher
flow cytometry; mouse	Billich A, Baumruker T, Beerli C, Bigaud M, Bruns C, Calzascia T, et al. Partial deficiency of sphingosine-1-phosphate lyase confers protection in experimental autoimmune encephalomyelitis. PLoS ONE. 2013;8:e59630 pubmed publisher
flow cytometry; mouse	Atkinson S, Usher P, Kvist P, Markholst H, Haase C, Nansen A. Establishment and characterization of a sustained delayed-type hypersensitivity model with arthritic manifestations in C57BL/6J mice. Arthritis Res Ther. 2012;14:R134 pubmed publisher
flow cytometry; mouse	Golias J, Schwarzer M, Wallner M, Kverka M, Kozakova H, Srůtková D, et al. Heat-induced structural changes affect OVA-antigen processing and reduce allergic response in mouse model of food allergy. PLoS ONE. 2012;7:e37156 pubmed publisher
	Hagert C, Bohn A, Wittenborn T, Degn S. Seeing the Confetti Colors in a New Light Utilizing Flow Cytometry and Imaging Flow Cytometry. Cytometry A. 2020;97:811-823 pubmed publisher
	Navarathna D, Lionakis M, Roberts D. Endothelial nitric oxide synthase limits host immunity to control disseminated Candida albicans infections in mice. PLoS ONE. 2019;14:e0223919 pubmed publisher
	Chisolm D, Cheng W, Colburn S, Silva Sanchez A, Meza Perez S, Randall T, et al. Defining Genetic Variation in Widely Used Congenic and Backcrossed Mouse Models Reveals Varied Regulation of Genes Important for Immune Responses. Immunity. 2019;51:155-168.e5 pubmed publisher
	Lucinda N, Figueiredo M, Pessoa N, Santos B, Lima G, Freitas A, et al. Dendritic cells, macrophages, NK and CD8+ T lymphocytes play pivotal roles in controlling HSV-1 in the trigeminal ganglia by producing IL1-beta, iNOS and granzyme B. Virol J. 2017;14:37 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD4 Monoclonal Antibody (RM4-5), Qdot™ 605

Catalog # :

Q10092

Quantity :

100 µL

Price :

US 562.00

Clonality :

Monoclonal

Purity :

purified

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: Assay-dependent

Species :

Mouse

Clone :

RM4-5

Isotype :

IgG2a

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].

Immunogen :

Mouse CD4

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-dependent

Aliases :

Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen

more info or order :

Invitrogen product webpage