CD14 Monoclonal Antibody (TuK4), Qdot™ 800 | Invitrogen Q10064 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD14 Monoclonal Antibody (TuK4), Qdot™ 800

catalog :

Q10064

quantity :

100 µL

price :

US 688.00

clonality :

monoclonal

host :

mouse

conjugate :

Qdot 800

clone name :

TUK4

reactivity :

human

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Deng N, Mosmann T. Optimization of the cytokine secretion assay for human IL-2 in single and combination assays. Cytometry A. 2015;87:777-83 pubmed publisher
flow cytometry; human	Kobie J, Treanor J, Ritchlin C. Transient decrease in human peripheral blood myeloid dendritic cells following influenza vaccination correlates with induction of serum antibody. Immunol Invest. 2014;43:606-15 pubmed publisher
flow cytometry; human; fig 1	Li X, Miao H, Henn A, Topham D, Wu H, Zand M, et al. Ki-67 expression reveals strong, transient influenza specific CD4 T cell responses after adult vaccination. Vaccine. 2012;30:4581-4 pubmed publisher
flow cytometry; human; fig 1	Scheible K, Zhang G, Baer J, Azadniv M, Lambert K, Pryhuber G, et al. CD8+ T cell immunity to 2009 pandemic and seasonal H1N1 influenza viruses. Vaccine. 2011;29:2159-68 pubmed publisher
	Rouers A, Chng M, Lee B, Rajapakse M, Kaur K, Toh Y, et al. Immune cell phenotypes associated with disease severity and long-term neutralizing antibody titers after natural dengue virus infection. Cell Rep Med. 2021;2:100278 pubmed publisher
	Kreutmair S, Unger S, Núñez N, Ingelfinger F, Alberti C, De Feo D, et al. Distinct immunological signatures discriminate severe COVID-19 from non-SARS-CoV-2-driven critical pneumonia. Immunity. 2021;54:1578-1593.e5 pubmed publisher
	Ong S, Hadadi E, Dang T, Yeap W, Tan C, Ng T, et al. The pro-inflammatory phenotype of the human non-classical monocyte subset is attributed to senescence. Cell Death Dis. 2018;9:266 pubmed publisher
	Zaal A, Dieker M, Oudenampsen M, Turksma A, Lissenberg Thunnissen S, Wouters D, et al. Anaphylatoxin C5a Regulates 6-Sulfo-LacNAc Dendritic Cell Function in Human through Crosstalk with Toll-Like Receptor-Induced CREB Signaling. Front Immunol. 2017;8:818 pubmed publisher
	Newell E, Yun L. Mass cytometry analysis of human T cell phenotype and function. Methods Mol Biol. 2014;1193:55-68 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD14 Monoclonal Antibody (TuK4), Qdot™ 800

Catalog # :

Q10064

Quantity :

100 µL

Price :

US 688.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: Assay-dependent

Species :

Human

Clone :

TuK4

Isotype :

IgG2a

Storage :

4° C, store in dark

Description :

CD14 is a 55 kDa GPI-anchored glycoprotein that is constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils. CD14 also serves as a multifunctional lipopolysaccharide receptor, and is released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 can discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. Further, CD14 has been shown to bind apoptotic cells, and can affect allergic, inflammatory and infectious processes. Alternative splicing results in multiple transcript variants encoding the same CD14 isoform. Diseases associated with CD14 dysfunction include mycobacterium chelonae infection and Croup.

Immunogen :

Tthe CD14 antigen

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-dependent

Aliases :

CD 14; CD14; CD14 antigen; CD14 molecule; cd14 monocyte; lipopolysaccharide receptor; lipoprotein receptor; LPSR antibody; monocyte differentiation antigen CD14; Monocyte differentiation antigen CD14, membrane-bound form; Monocyte differentiation antigen CD14, urinary form; monocyte differentiation antigen CD14; LOW QUALITY PROTEIN: monocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein; myeloid membrane glycoprotein precursor; sCD14; soluble CD14

more info or order :

Invitrogen product webpage