Human EGFR (ErbB1) [L858R], GST Tag Recombinant Protein | Invitrogen PR7447A product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Human EGFR (ErbB1) [L858R], GST Tag Recombinant Protein

catalog :

PR7447A

quantity :

100 ug

price :

US 2060.00

product information

Product Type :

Protein

Product Name :

Human EGFR (ErbB1) [L858R], GST Tag Recombinant Protein

Catalog # :

PR7447A

Quantity :

100 ug

Price :

US 2060.00

Clonality :

Recombinant

Purity :

purified

Reactivity :

Human

Applications :

Kinase Assay: Assay-dependent

Species :

Human

Storage :

-80 C, Avoid Freeze/Thaw Cycles

Description :

EGFR, epidermal growth factor receptor, is a receptor tyrosine kinases that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. EGFR is encoded by the EGFR gene located on chromosome 7 in humans. EGFR belongs to the HER/ERbB family of proteins that includes three other receptor tyrosine kinases, ERbB2, ERbB3, ERbB4. EGFR is a transmembrane receptor and binding of its cognate ligands such as EGF (Epidermal Growth Factor) and TGF alpha (Transforming Growth Factor alpha) to the extracellular domain leads to EGFR dimerization followed by autophosphorylation of the tyrosine residues in the cytoplasmic domain. Overexpression is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.

Format :

Liquid

Applications w/Dilutions :

Kinase Assay: Assay-dependent

Aliases :

EGFR; Erbb1