This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
protein
product name :
Human Heat Stable bFGF Recombinant Protein
catalog :
PHG0367
quantity :
5 ug
price :
US 112.00
citations: 17
Reference
Luan Y, Zhang H, Ma K, Liu Y, Lu H, Chen X, et al. CCN3/NOV Regulates Proliferation and Neuronal Differentiation in Mouse Hippocampal Neural Stem Cells via the Activation of the Notch/PTEN/AKT Pathway. Int J Mol Sci. 2023;24: pubmed publisher
Mukherjee A, Dianatdar A, G x142 adysz M, Hemmatpour H, Hendriksen M, Rudolf P, et al. Electrically Conductive and Highly Stretchable Piezoresistive Polymer Nanocomposites via Oxidative Chemical Vapor Deposition. ACS Appl Mater Interfaces. 2023;15:31899-31916 pubmed publisher
Monaco C, Plewes M, Przygrodzka E, George J, Qiu F, Xiao P, et al. Basic fibroblast growth factor induces proliferation and collagen production by fibroblasts derived from the bovine corpus luteum†. Biol Reprod. 2023;109:367-380 pubmed publisher
Barisas D, Kabir A, Wu J, Krchma K, Kim M, Subramanian M, et al. Tumor-derived interleukin-1α and leukemia inhibitory factor promote extramedullary hematopoiesis. PLoS Biol. 2023;21:e3001746 pubmed publisher
Slota J, Wang X, Lusansky D, Medina S, Booth S. Differentiated cultures of an immortalized human neural progenitor cell line do not replicate prions despite PrPC overexpression. Prion. 2023;17:116-132 pubmed publisher
Hong Y, Dong X, Chang L, Xie C, Chang M, Aguilar J, et al. Microglia-containing cerebral organoids derived from induced pluripotent stem cells for the study of neurological diseases. iScience. 2023;26:106267 pubmed publisher
Murphy C, Naderlinger E, Mater A, Kluin R, Wilmes A. Comparison of human recombinant protein coatings and fibroblast-ECM to Matrigel for induced pluripotent stem cell culture and renal podocyte differentiation. ALTEX. 2023;40:141-159 pubmed publisher
Kanno S, Okubo Y, Kageyama T, Yan L, Kitajima S, Fukuda J. Establishment of a developmental toxicity assay based on human iPSC reporter to detect FGF signal disruption. iScience. 2022;25:103770 pubmed publisher
Xu E, Hu M, Ge R, Tong D, Fan Y, Ren X, et al. LncRNA-42060 Regulates Tamoxifen Sensitivity and Tumor Development via Regulating the miR-204-5p/SOX4 Axis in Canine Mammary Gland Tumor Cells. Front Vet Sci. 2021;8:654694 pubmed publisher
Mutukula N, Man Z, Takahashi Y, Iniesta Martínez F, Morales M, Carreón Guarnizo E, et al. Generation of RRMS and PPMS specific iPSCs as a platform for modeling Multiple Sclerosis. Stem Cell Res. 2021;53:102319 pubmed publisher
Chen G, An N, Ye W, Huang S, Chen Y, Hu Z, et al. bFGF alleviates diabetes-associated endothelial impairment by downregulating inflammation via S-nitrosylation pathway. Redox Biol. 2021;41:101904 pubmed publisher
Deng M, Xie P, Chen Z, Zhou Y, Liu J, Ming J, et al. Mash-1 modified neural stem cells transplantation promotes neural stem cells differentiation into neurons to further improve locomotor functional recovery in spinal cord injury rats. Gene. 2021;781:145528 pubmed publisher
Schädli G, Vetsch J, Baumann R, de Leeuw A, Wehrle E, Rubert M, et al. Time-lapsed imaging of nanocomposite scaffolds reveals increased bone formation in dynamic compression bioreactors. Commun Biol. 2021;4:110 pubmed publisher
Feng X, Chen P, Zhao X, Wang J, Wang H. Transplanted embryonic retinal stem cells have the potential to repair the injured retina in mice. BMC Ophthalmol. 2021;21:26 pubmed publisher
Rakipovski G, Rolin B, Barascuk N, Lund H, Bjørn Bonde M, Djordjevic D, et al. A neutralizing antibody against DKK1 does not reduce plaque formation in classical murine models of atherosclerosis: Is the therapeutic potential lost in translation?. Atherosclerosis. 2020;314:1-9 pubmed publisher
Liang Y, Deng X, Lin X, Jiang L, Huang X, Mo Z, et al. RASSF1A inhibits PDGFB-driven malignant phenotypes of nasopharyngeal carcinoma cells in a YAP1-dependent manner. Cell Death Dis. 2020;11:855 pubmed publisher
Saito K, Okamoto M, Watanabe Y, Noguchi N, Nagasaka A, Nishina Y, et al. Dorsal-to-Ventral Cortical Expansion Is Physically Primed by Ventral Streaming of Early Embryonic Preplate Neurons. Cell Rep. 2019;29:1555-1567.e5 pubmed publisher
product information
Product Type :
Protein
Product Name :
Human Heat Stable bFGF Recombinant Protein
Catalog # :
PHG0367
Quantity :
5 ug
Price :
US 112.00
Clonality :
Recombinant
Purity :
purified
Reactivity :
Human
Applications :
Control: Assay-dependent, ELISA: Assay-dependent, Functional Assay: Assay-dependent, Immunohistochemistry: Assay-dependent, Western Blot: Assay-dependent
Species :
Human
Storage :
-20 C
Description :
FGF2 (FGFb, fibroblast growth factor basic) belongs to the fibroblast growth factor (FGF) family, and interacts with high-affinity transmembrane receptors to influence cell proliferation and tissue neovascularization. FGF2 exists as five isoforms with distinct intracellular localizations and functions. The 18 kDa isoform is predominantly cytosolic and acts through cell surface receptors, whereas the 22, 22.5, 24 and 34 kDa isoforms are nuclear and may signal independent of transmembrane receptor pathways. In humans, the gene is located on the q arm of chromosome 4. FGF2 has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for FGF2 contains multiple polyadenylation sites, and is alternatively translated from non-AUG and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. Diseases associated with FGF2 dysfunction include Kaposi Sarcoma and corneal neovascularization.
Format :
Lyophilized
Applications w/Dilutions :
Control: Assay-dependent, ELISA: Assay-dependent, Functional Assay: Assay-dependent, Immunohistochemistry: Assay-dependent, Western Blot: Assay-dependent
Aliases :
Basic fibroblast growth factor; basic fibroblast growth factor bFGF; bFGF; FGF; fgf basic; Fgf2; Fgf-2; Fgfb; FGF-b; Fibroblast growth factor; fibroblast growth factor 2; fibroblast growth factor 2 (basic); Fibroblast growth factor basic; HBGF-2; Heparin-binding growth factor 2; H-FGF-b-147; H-FGF-b-154; M-FGF-b; Prostatic growth factor; prostatropin
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA