This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
protein
product name :
Human FGF-basic (FGF-2/bFGF) (aa 1-155) Recombinant Protein
catalog :
PHG0264
quantity :
10 ug
price :
US 145.00
citations: 34
Reference
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Wu C, Hu B, Wang L, Wu X, Gu H, Dong H, et al. Assessment of stromal SCD-induced drug resistance of PDAC using 3D-printed zPDX model chips. iScience. 2023;26:105723 pubmed publisher
Leong E, Khaing N, Cadot B, Hong W, Kozlov S, Werner H, et al. Nesprin-1 LINC complexes recruit microtubule cytoskeleton proteins and drive pathology in Lmna-mutant striated muscle. Hum Mol Genet. 2023;32:177-191 pubmed publisher
Borkowska P, Morys J, Zielińska A, Sadlocha M, Kowalski J. Survival and Neurogenesis-Promoting Effects of the Co-Overexpression of BCLXL and BDNF Genes on Wharton's Jelly-Derived Mesenchymal Stem Cells. Life (Basel). 2022;12: pubmed publisher
Mazurek S, Oleksiewicz U, Czerwińska P, Wroblewska J, Klimczak M, Wiznerowicz M. Disruption of RING and PHD Domains of TRIM28 Evokes Differentiation in Human iPSCs. Cells. 2021;10: pubmed publisher
Borkowska P, Zielińska A, Paul Samojedny M, Stojko R, Kowalski J. Synergistic Effect of the Long-Term Overexpression of Bcl-2 and BDNF Lentiviral in Cell Protecting against Death and Generating TH Positive and CHAT Positive Cells from MSC. Int J Mol Sci. 2021;22: pubmed publisher
Ucuncu E, Rajamani K, Wilson M, Medina Cano D, Altin N, David P, et al. MINPP1 prevents intracellular accumulation of the chelator inositol hexakisphosphate and is mutated in Pontocerebellar Hypoplasia. Nat Commun. 2020;11:6087 pubmed publisher
Glorieux C, Xia X, He Y, Hu Y, Cremer K, Robert A, et al. Regulation of PD-L1 expression in K-ras-driven cancers through ROS-mediated FGFR1 signaling. Redox Biol. 2021;38:101780 pubmed publisher
Li J, Shang Y, Wang L, Zhao B, Sun C, Li J, et al. Genome integrity and neurogenesis of postnatal hippocampal neural stem/progenitor cells require a unique regulator Filia. Sci Adv. 2020;6: pubmed publisher
Cowan C, Renner M, De Gennaro M, Gross Scherf B, Goldblum D, Hou Y, et al. Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution. Cell. 2020;182:1623-1640.e34 pubmed publisher
Chennakrishnaiah S, Tsering T, Gregory C, Tawil N, Spinelli C, Montermini L, et al. Extracellular vesicles from genetically unstable, oncogene-driven cancer cells trigger micronuclei formation in endothelial cells. Sci Rep. 2020;10:8532 pubmed publisher
Sharma Y, Saha S, Joseph A, Krishnan H, Raghu P. In vitro human stem cell derived cultures to monitor calcium signaling in neuronal development and function. Wellcome Open Res. 2020;5:16 pubmed publisher
Datta D, Vasudevan A. Migration, Chemo-Attraction, and Co-Culture Assays for Human Stem Cell-Derived Endothelial Cells and GABAergic Neurons. J Vis Exp. 2020;: pubmed publisher
Dong C, Beltcheva M, Gontarz P, Zhang B, Popli P, Fischer L, et al. Derivation of trophoblast stem cells from naïve human pluripotent stem cells. elife. 2020;9: pubmed publisher
Bendriem R, Singh S, Aleem A, Antonetti D, Ross M. Tight junction protein occludin regulates progenitor Self-Renewal and survival in developing cortex. elife. 2019;8: pubmed publisher
Wang X, Williams D, Muller I, Lemieux M, Dukart R, Maia I, et al. Tau interactome analyses in CRISPR-Cas9 engineered neuronal cells reveal ATPase-dependent binding of wild-type but not P301L Tau to non-muscle myosins. Sci Rep. 2019;9:16238 pubmed publisher
Su W, Han H, Wang Y, Zhang B, Zhou B, Cheng Y, et al. The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression. Cancer Cell. 2019;36:139-155.e10 pubmed publisher
Akutsu H, Nasu M, Morinaga S, Motoyama T, Homma N, Machida M, et al. In vivo maturation of human embryonic stem cell-derived teratoma over time. Regen Ther. 2016;5:31-39 pubmed publisher
Akutsu H, Machida M, Kanzaki S, Sugawara T, Ohkura T, Nakamura N, et al. Xenogeneic-free defined conditions for derivation and expansion of human embryonic stem cells with mesenchymal stem cells. Regen Ther. 2015;1:18-29 pubmed publisher
Teow S, Liew K, Che Mat M, Marzuki M, Abdul Aziz N, Chu T, et al. Development of a luciferase/luciferin cell proliferation (XenoLuc) assay for real-time measurements of Gfp-Luc2-modified cells in a co-culture system. BMC Biotechnol. 2019;19:34 pubmed publisher
Wang H, Xiao Z, Zheng J, Wu J, Hu X, Yang X, et al. ZEB1 Represses Neural Differentiation and Cooperates with CTBP2 to Dynamically Regulate Cell Migration during Neocortex Development. Cell Rep. 2019;27:2335-2353.e6 pubmed publisher
MacArthur C, Pradhan S, Wetton N, Zarrabi A, Dargitz C, Sridharan M, et al. Generation and comprehensive characterization of induced pluripotent stem cells for translational research. Regen Med. 2019;14:505-524 pubmed publisher
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product information
Product Type :
Protein
Product Name :
Human FGF-basic (FGF-2/bFGF) (aa 1-155) Recombinant Protein
Catalog # :
PHG0264
Quantity :
10 ug
Price :
US 145.00
Clonality :
Recombinant
Purity :
purified
Reactivity :
Human
Applications :
Control: Assay-dependent, ELISA: Assay-dependent, Functional Assay: Assay-dependent, Immunohistochemistry: Assay-dependent, Western Blot: Assay-dependent
Species :
Human
Storage :
4 C
Description :
FGF2 (FGFb, fibroblast growth factor basic) belongs to the fibroblast growth factor (FGF) family, and interacts with high-affinity transmembrane receptors to influence cell proliferation and tissue neovascularization. FGF2 exists as five isoforms with distinct intracellular localizations and functions. The 18 kDa isoform is predominantly cytosolic and acts through cell surface receptors, whereas the 22, 22.5, 24 and 34 kDa isoforms are nuclear and may signal independent of transmembrane receptor pathways. In humans, the gene is located on the q arm of chromosome 4. FGF2 has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for FGF2 contains multiple polyadenylation sites, and is alternatively translated from non-AUG and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. Diseases associated with FGF2 dysfunction include Kaposi Sarcoma and corneal neovascularization.
Format :
Lyophilized
Applications w/Dilutions :
Control: Assay-dependent, ELISA: Assay-dependent, Functional Assay: Assay-dependent, Immunohistochemistry: Assay-dependent, Western Blot: Assay-dependent
Aliases :
Basic fibroblast growth factor; basic fibroblast growth factor bFGF; bFGF; FGF; fgf basic; Fgf2; Fgf-2; Fgfb; FGF-b; Fibroblast growth factor; fibroblast growth factor 2; fibroblast growth factor 2 (basic); Fibroblast growth factor basic; HBGF-2; Heparin-binding growth factor 2; H-FGF-b-147; H-FGF-b-154; M-FGF-b; Prostatic growth factor; prostatropin
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA