Human FGF-basic (FGF-2/bFGF) (aa 10-155) Recombinant Protein | Invitrogen PHG0026 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Human FGF-basic (FGF-2/bFGF) (aa 10-155) Recombinant Protein

catalog :

PHG0026

quantity :

50 ug

price :

US 526.00

citations: 7

Reference
Zhang S, Yang F, Huang Y, He L, Li Y, Wan Y, et al. ATF3 induction prevents precocious activation of skeletal muscle stem cell by regulating H2B expression. Nat Commun. 2023;14:4978 pubmed publisher
So K, Huang Y, Zhang S, Qiao Y, He L, Li Y, et al. seRNA PAM controls skeletal muscle satellite cell proliferation and aging through trans regulation of Timp2 expression synergistically with Ddx5. Aging Cell. 2022;21:e13673 pubmed publisher
Bauer U, Fiskum V, Nair R, van de Wijdeven R, Kentros C, Sandvig I, et al. Validation of Functional Connectivity of Engineered Neuromuscular Junction With Recombinant Monosynaptic Pseudotyped ΔG-Rabies Virus Tracing. Front Integr Neurosci. 2022;16:855071 pubmed publisher
Wang H, Gong P, Chen T, Gao S, Wu Z, Wang X, et al. Colorectal Cancer Stem Cell States Uncovered by Simultaneous Single-Cell Analysis of Transcriptome and Telomeres. Adv Sci (Weinh). 2021;8:2004320 pubmed publisher
Hunter S, McIntosh B, Shi Y, Sperberg R, Funatogawa C, Labanieh L, et al. An engineered ligand trap inhibits leukemia inhibitory factor as pancreatic cancer treatment strategy. Commun Biol. 2021;4:452 pubmed publisher
Ma S, Sun R, Jiang B, Gao J, Deng W, Liu P, et al. L2hgdh Deficiency Accumulates l-2-Hydroxyglutarate with Progressive Leukoencephalopathy and Neurodegeneration. Mol Cell Biol. 2017;37: pubmed publisher
Ahmadian Baghbaderani B, Tian X, Scotty Cadet J, Shah K, Walde A, Tran H, et al. A Newly Defined and Xeno-Free Culture Medium Supports Every-Other-Day Medium Replacement in the Generation and Long-Term Cultivation of Human Pluripotent Stem Cells. PLoS ONE. 2016;11:e0161229 pubmed publisher

product information

Product Type :

Protein

Product Name :

Human FGF-basic (FGF-2/bFGF) (aa 10-155) Recombinant Protein

Catalog # :

PHG0026

Quantity :

50 ug

Price :

US 526.00

Clonality :

Recombinant

Purity :

purified

Reactivity :

Human

Applications :

Control: Assay-dependent, ELISA: Assay-dependent, Functional Assay: Assay-dependent, Immunohistochemistry: Assay-dependent, Western Blot: Assay-dependent

Species :

Human

Storage :

4 C

Description :

FGF2 (FGFb, fibroblast growth factor basic) belongs to the fibroblast growth factor (FGF) family, and interacts with high-affinity transmembrane receptors to influence cell proliferation and tissue neovascularization. FGF2 exists as five isoforms with distinct intracellular localizations and functions. The 18 kDa isoform is predominantly cytosolic and acts through cell surface receptors, whereas the 22, 22.5, 24 and 34 kDa isoforms are nuclear and may signal independent of transmembrane receptor pathways. In humans, the gene is located on the q arm of chromosome 4. FGF2 has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for FGF2 contains multiple polyadenylation sites, and is alternatively translated from non-AUG and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. Diseases associated with FGF2 dysfunction include Kaposi Sarcoma and corneal neovascularization.

Format :

Lyophilized

Applications w/Dilutions :

Control: Assay-dependent, ELISA: Assay-dependent, Functional Assay: Assay-dependent, Immunohistochemistry: Assay-dependent, Western Blot: Assay-dependent

Aliases :

Basic fibroblast growth factor; basic fibroblast growth factor bFGF; bFGF; FGF; fgf basic; Fgf2; Fgf-2; Fgfb; FGF-b; Fibroblast growth factor; fibroblast growth factor 2; fibroblast growth factor 2 (basic); Fibroblast growth factor basic; HBGF-2; Heparin-binding growth factor 2; H-FGF-b-147; H-FGF-b-154; M-FGF-b; Prostatic growth factor; prostatropin