Human EPO (Erythropoietin) Recombinant Protein | Invitrogen PHC2054 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Human EPO (Erythropoietin) Recombinant Protein

catalog :

PHC2054

quantity :

500 IU

price :

US 694.00

citations: 5

Reference
Mirmiran A, Poli A, Ged C, Schmitt C, Lefebvre T, Manceau H, et al. Phlebotomy as an efficient long-term treatment of congenital erythropoietic porphyria. Haematologica. 2021;106:913-917 pubmed publisher
Jennbacken K, Wagberg F, Karlsson U, Eriksson J, Magnusson L, Chimienti M, et al. Phenotypic Screen with the Human Secretome Identifies FGF16 as Inducing Proliferation of iPSC-Derived Cardiac Progenitor Cells. Int J Mol Sci. 2019;20: pubmed publisher
Schulz V, Yan H, Lezon Geyda K, An X, Hale J, Hillyer C, et al. A Unique Epigenomic Landscape Defines Human Erythropoiesis. Cell Rep. 2019;28:2996-3009.e7 pubmed publisher
Xu M, Luk W, Bi C, Liu E, Wu K, Yao P, et al. Erythropoietin regulates the expression of dimeric form of acetylcholinesterase during differentiation of erythroblast. J Neurochem. 2018;146:390-402 pubmed publisher
Inlay M, Serwold T, Mosley A, Fathman J, Dimov I, Seita J, et al. Identification of multipotent progenitors that emerge prior to hematopoietic stem cells in embryonic development. Stem Cell Reports. 2014;2:457-72 pubmed publisher

product information

Product Type :

Protein

Product Name :

Human EPO (Erythropoietin) Recombinant Protein

Catalog # :

PHC2054

Quantity :

500 IU

Price :

US 694.00

Clonality :

Recombinant

Purity :

purified

Reactivity :

Human

Applications :

Control: Assay-dependent, ELISA: Assay-dependent, Functional Assay: Assay-dependent, Immunohistochemistry: Assay-dependent, Western Blot: Assay-dependent

Species :

Human

Storage :

-20 C

Description :

Erythropoietin (EPO) protein is a growth factor essential for the survival, proliferation, and differentiation of erythroid precursors. EPO is not responsible for early commitment to the lineage, and instead induces the final maturation of partially differentiated erythroid cells and the production of red cell-specific proteins, such as hemoglobin. The EPO receptor (EPOR) is present in higher levels on precursor cells, and expression diminishes with cell maturation.Hepatocytes are the main source of EPO in the fetus, followed by interstitial cells of the kidney after birth and through adulthood. EPO expression is upregulated during hypoxia, and low levels of transcription have also been detected in lung and brain tissue under these conditions. Recent data suggest that EPO may also play a role in the protection of neuronal tissue from damage and initiation of repair.

Format :

Lyophilized

Applications w/Dilutions :

Control: Assay-dependent, ELISA: Assay-dependent, Functional Assay: Assay-dependent, Immunohistochemistry: Assay-dependent, Western Blot: Assay-dependent

Aliases :

EP; EPO; Epoetin; erythropoietin; MGC138142; MVCD2