Human IL-3 Recombinant Protein | Invitrogen PHC0031 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Human IL-3 Recombinant Protein

catalog :

PHC0031

quantity :

100 ug

price :

US 1224.00

citations: 6

Reference
Benito Kwiecinski S, Giandomenico S, Sutcliffe M, Riis E, Freire Pritchett P, Kelava I, et al. An early cell shape transition drives evolutionary expansion of the human forebrain. Cell. 2021;184:2084-2102.e19 pubmed publisher
Datta I, Jagtap S, Sowmithra -, Yadav R, Pal P. Generation of induced pluripotent stem cells (NIMHi002-A and NIMHi003-A) from two sporadic Parkinson's disease patient of East Indian ethnicity. Stem Cell Res. 2020;49:101995 pubmed publisher
Grubman A, Vandekolk T, Schröder J, Sun G, Hatwell Humble J, Chan J, et al. A CX3CR1 Reporter hESC Line Facilitates Integrative Analysis of In-Vitro-Derived Microglia and Improved Microglia Identity upon Neuron-Glia Co-culture. Stem Cell Reports. 2020;14:1018-1032 pubmed publisher
Datta I, Sowmithra -, Jagtap S, Potdar C, Yadav R, Pal P. Generation of induced pluripotent stem cells (NIMHi001-A) from a Parkinson's disease patient of East Indian ethnicity carrying LRRK2 I1371V variant. Stem Cell Res. 2020;44:101768 pubmed publisher
Künzel U, Grieve A, Meng Y, Sieber B, Cowley S, Freeman M. FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex. elife. 2018;7: pubmed publisher
Abud E, Ramirez R, Martinez E, Healy L, Nguyen C, Newman S, et al. iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases. Neuron. 2017;94:278-293.e9 pubmed publisher

product information

Product Type :

Protein

Product Name :

Human IL-3 Recombinant Protein

Catalog # :

PHC0031

Quantity :

100 ug

Price :

US 1224.00

Clonality :

Recombinant

Purity :

purified

Reactivity :

Human

Applications :

Control: Assay-dependent, ELISA: Assay-dependent, Functional Assay: Assay-dependent, Immunohistochemistry: Assay-dependent, Western Blot: Assay-dependent

Species :

Human

Storage :

4 C

Description :

Interleukin 3 (IL-3), also called Mast Cell Growth Factor (MCGF), Multi-Colony Stimulating Factor (multi-CSF), or Eosinophil-CSF (E-CSF), is produced by activated T cells, mast cells and eosinophils. IL-3 is a hematopoietic growth factor that stimulates colony formation of erythroid, megakaryocyte, neutrophil, eosinophil, basophil, mast cell and monocytic lineages. Most of these functions are enhanced or dependent on co-stimulation with other cytokines. Human and mouse IL-3 share only 29% sequence identity at the amino acid level. The bioactivity of IL-3 is highly species specific. For example, human IL-3 has no activity on mouse cells. IL-3 is a potent growth promoting cytokine. IL-3 is capable of supporting the proliferation of a broad range of hematopoietic cell types, and is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.

Format :

Lyophilized

Applications w/Dilutions :

Control: Assay-dependent, ELISA: Assay-dependent, Functional Assay: Assay-dependent, Immunohistochemistry: Assay-dependent, Western Blot: Assay-dependent

Aliases :

BP/BPA; BPA; Colony stimulating factor multiple; colony-stimulating factor, multiple; Csfmu; Eo-CSF; HCGF; hematopoietic growth factor; Il3; Il-3; ILN; Interleukin; interleukin 3; Interleukin 3 (colony stimulating factor; Interleukin3; interleukin-3; Mast cell growth factor; mast-cell growth factor; MCGF; MGC79398; MGC79399; MGF; Multi CSF; MULTI-CSF; Multilineage colony stimulating factor; multilineage-colony-stimulating factor; multiple); multipotential colony-stimulating factor; P cell stimulating factor; P-cell stimulating factor; P-cell-stimulating factor; PCSA; PSF