This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
protein
product name :
Human IL-2 Recombinant Protein
catalog :
PHC0021
quantity :
100 ug
price :
US 892.00
citations: 7
Reference
Peng W, Ye L, Xue Q, Wei X, Wang Z, Xiang X, et al. Silencing of circCRIM1 Drives IGF2BP1-Mediated NSCLC Immune Evasion. Cells. 2023;12: pubmed publisher
Liu M, Wu C, Luo S, Hua Q, Chen H, Weng Y, et al. PERK reprograms hematopoietic progenitor cells to direct tumor-promoting myelopoiesis in the spleen. J Exp Med. 2022;219: pubmed publisher
Wang Y, Gu T, Tian X, Li W, Zhao R, Yang W, et al. A Small Molecule Antagonist of PD-1/PD-L1 Interactions Acts as an Immune Checkpoint Inhibitor for NSCLC and Melanoma Immunotherapy. Front Immunol. 2021;12:654463 pubmed publisher
Valle S, Alcala S, Martin Hijano L, Cabezas Sainz P, Navarro D, Muñoz E, et al. Exploiting oxidative phosphorylation to promote the stem and immunoevasive properties of pancreatic cancer stem cells. Nat Commun. 2020;11:5265 pubmed publisher
Wang C, Weng M, Xia S, Zhang M, Chen C, Tang J, et al. Distinct roles of programmed death ligand 1 alternative splicing isoforms in colorectal cancer. Cancer Sci. 2021;112:178-193 pubmed publisher
Ding N, Hua J, He J, Lu D, Wei W, Zhang Y, et al. The Role of MiR-5094 as a Proliferation Suppressor during Cellular Radiation Response via Downregulating STAT5b. J Cancer. 2020;11:2222-2233 pubmed publisher
Liao Z, Muth D, Eitan E, Travers M, Learman L, Lehrmann E, et al. Serum extracellular vesicle depletion processes affect release and infectivity of HIV-1 in culture. Sci Rep. 2017;7:2558 pubmed publisher
product information
Product Type :
Protein
Product Name :
Human IL-2 Recombinant Protein
Catalog # :
PHC0021
Quantity :
100 ug
Price :
US 892.00
Clonality :
Recombinant
Purity :
purified
Reactivity :
Human
Applications :
Control: Assay-dependent, ELISA: Assay-dependent, Functional Assay: Assay-dependent, Immunohistochemistry: Assay-dependent, Western Blot: Assay-dependent
Species :
Human
Storage :
4 C
Description :
Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.
Format :
Lyophilized
Applications w/Dilutions :
Control: Assay-dependent, ELISA: Assay-dependent, Functional Assay: Assay-dependent, Immunohistochemistry: Assay-dependent, Western Blot: Assay-dependent
Aliases :
aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA