This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
protein
product name :
Human beta-Arrestin 2 (aa 384-397) Synthetic Peptide
catalog :
PEP-156
quantity :
50 µg
price :
US 140.00
product information
Product Type :
Peptide
Product Name :
Human beta-Arrestin 2 (aa 384-397) Synthetic Peptide
Catalog # :
PEP-156
Quantity :
50 µg
Price :
US 140.00
Clonality :
Synthetic
Purity :
purified
Reactivity :
Human
Applications :
Control: Assay-dependent
Species :
Human
Storage :
-20° C, Avoid Freeze/Thaw Cycles
Description :
Beta-arrestin-2, or ARRB2, is an adaptor protein belonging to the arrestin family with an N- arrestin domain and a C- arrestin domain. ARRB2 is a regulatory protein involved in heterotrimeric G protein-coupled receptor desensitization and is known to regulate beta2-adrenergic receptor (beta2AR) function by enhancing beta2AR mediated nuclear translocation of ERK. ARRB2 binds to phosphorylated beta2ARs, thereby causing a significant impairment of their capacity to activate G(S) proteins. Along with AIP4, ARRB2 acts as an endosomal sorting molecule that mediates CXCR4 entry into a degradative pathway. It may also be involved in hormone-specific desensitization of TSH receptors. ARRB2 is a Ca2+ binding protein of the retinal outer segments and binds to P-rhodopsin and is also involved in synaptic transmission in photoreceptor cells. It is widely expressed in most of the tissues, especially neuronal tissues and spleen.
Format :
Lyophilized
Applications w/Dilutions :
Control: Assay-dependent
Aliases :
AI326910; ARB2; ARR2; ARRB2; arrestin; arrestin 3; arrestin beta 2; arrestin beta-2; arrestin, beta 2; arrestin-3; AW122872; BARR2; BARRES; beta arr2; beta-arrestin 2; beta-arrestin 2 long isoform; beta-arrestin 2 short isoform; beta-arrestin2; beta-arrestin-2; DKFZp686L0365; HGNC:712; Non-visual arrestin-3; SAG; S-Arrestin
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA