Human TIP47 Synthetic Peptide | Invitrogen PEP-0388 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Human TIP47 Synthetic Peptide

catalog :

PEP-0388

quantity :

50 ug

price :

US 167.00

product information

Product Type :

Peptide

Product Name :

Human TIP47 Synthetic Peptide

Catalog # :

PEP-0388

Quantity :

50 ug

Price :

US 167.00

Clonality :

Synthetic

Purity :

purified

Reactivity :

Human

Applications :

Blocking Assay: Assay-dependent, Control: Assay-dependent

Species :

Human

Storage :

-20 C

Description :

TIP47 has been described as cargo protein involved in the trafficking of the mannose-6-phosphate receptor between endosomes and the Golgi complex. Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs and is required for endosome to Golgi transport. This protein also binds directly to the GTPase RAB9, a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. TIP47 has been localized in milk fat globule membranes of human and bovine origin. It has been described as a placental protein, as well. Increased amounts of TIP47 are secreted into circulation of cervix carcinoma patients. Therefore, this protein is probably significant as an oncodevelopmental marker.

Format :

Liquid

Applications w/Dilutions :

Blocking Assay: Assay-dependent, Control: Assay-dependent

Aliases :

1300012C15Rik; 47 kDa mannose 6-phosphate receptor-binding protein; 47 kDa MPR-binding protein; 47 kDa tail interaction protein; cargo selection protein TIP47; M6prbp1; mannose 6 phosphate receptor binding protein 1; mannose-6-phosphate receptor binding protein 1; mannose-6-phosphate receptor-binding protein 1; MGC11117; MGC2012; perilipin 3; perilipin-3; Placental protein 17; Plin3; PP17; tail-interacting protein, 47 kD; testicular tissue protein Li 114; TIP47; Unknown (protein for MGC:128897)