This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
protein
product name :
Human PHAP Synthetic Peptide
catalog :
PEP-0143
quantity :
50 ug
price :
US 167.00
product information
Product Type :
Peptide
Product Name :
Human PHAP Synthetic Peptide
Catalog # :
PEP-0143
Quantity :
50 ug
Price :
US 167.00
Clonality :
Synthetic
Purity :
purified
Reactivity :
Human
Applications :
Blocking Assay: Assay-dependent, Control: Assay-dependent
Species :
Human
Storage :
-20 C
Description :
Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.
Format :
Liquid
Applications w/Dilutions :
Blocking Assay: Assay-dependent, Control: Assay-dependent
Aliases :
2410015B15Rik; 2810018A15Rik; Acid nuclear phosphoprotein 32 (leucine rich); acidic (leucine-rich) nuclear phosphoprotein 32 family, member A; acidic (leucine-rich) nuclear phosphoprotein 32 family, member B; acidic (leucine-rich) nuclear phosphoprotein 32 family, member D; acidic (leucine-rich) nuclear phosphoprotein 32 family, member E; acidic leucine-rich nuclear phosphoprotein 32 family member A; Acidic leucine-rich nuclear phosphoprotein 32 family member B; acidic leucine-rich nuclear phosphoprotein 32 family member E; acidic nuclear phosphoprotein 32; acidic nuclear phosphoprotein 32 family member A; acidic nuclear phosphoprotein 32 family member B; acidic nuclear phosphoprotein 32 family member E; acidic nuclear phosphoprotein 32 family, member A; acidic nuclear phosphoprotein 32 family, member B; acidic nuclear phosphoprotein pp32; Acidic protein rich in leucines; AI047746; AI326868; Anp32; Anp32a; Anp32b; ANP32D; ANP32E; APRIL; C15orf1; cerebellar leucine rich acidic nuclear protein; cerebellar postnatal development protein 1; Cpd1; hepatopoietin Cn; HPPCn; hypothetical protein LOC509685; I1PP2A; inhibitor-1 of protein phosphatase-2A; LANP; LANPL; LANP-L; LANP-like protein; Leucine-rich acidic nuclear protein; leucine-rich acidic nuclear protein LANP; leucine-rich acidic nuclear protein like; MAPM; Mapmodulin; mLANP-L; Pal31; PHAP1; PHAPI; PHAPI2; PHAPI2a; Potent heat-stable protein phosphatase 2A inhibitor I1PP2A; PP32; proliferation related acidic leucine rich protein PAL31; proliferation-related acidic leucine-rich protein PAL31; Putative HLA-DR-associated protein I; putative HLA-DR-associated protein I-2; putative human HLA class II associated protein I; silver-stainable protein SSP29; SSP29; vacidic (leucine-rich) nuclear phosphoprotein 32 family, member A; W91701
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com81 Wyman Street
Waltham, MA USA 02451
800-678-5599
headquarters: USA
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