PCNA Monoclonal Antibody (PC10), FITC | Invitrogen PCNA01 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PCNA Monoclonal Antibody (PC10), FITC

catalog :

PCNA01

quantity :

500 uL

price :

US 368.00

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

PC10

reactivity :

human, rat

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 3c	Morris K, Khan H, Ahmad A, Weston L, Nofchissey R, Pinchuk I, et al. G-CSF and G-CSFR are highly expressed in human gastric and colon cancers and promote carcinoma cell proliferation and migration. Br J Cancer. 2014;110:1211-20 pubmed publisher
flow cytometry; human; fig 4	Jiang N, Kham S, Koh G, Suang Lim J, Ariffin H, Chew F, et al. Identification of prognostic protein biomarkers in childhood acute lymphoblastic leukemia (ALL). J Proteomics. 2011;74:843-57 pubmed publisher
flow cytometry; human; fig 1	Naora H, Gougeon M. Enhanced survival and potent expansion of the natural killer cell population of HIV-infected individuals by exogenous interleukin-15. Immunol Lett. 1999;68:359-67 pubmed
	Rydell TÃ¶rmÃ¤nen K, AndrÃ©asson K, Hesselstrand R, Westergren Thorsson G. Absence of fibromodulin affects matrix composition, collagen deposition and cell turnover in healthy and fibrotic lung parenchyma. Sci Rep. 2014;4:6383 pubmed publisher
	Striedter G, Charvet C. Developmental origins of species differences in telencephalon and tectum size: morphometric comparisons between a parakeet (Melopsittacus undulatus) and a quail (Colinus virgianus). J Comp Neurol. 2008;507:1663-75 pubmed publisher

product information

Product Type :

Antibody

Product Name :

PCNA Monoclonal Antibody (PC10), FITC

Catalog # :

PCNA01

Quantity :

500 uL

Price :

US 368.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human, Rat

Applications :

Flow Cytometry: Assay-Dependent

Species :

Human, Rat

Clone :

PC10

Isotype :

IgG2a

Storage :

4 C, store in dark

Description :

PCNA (polymerase delta auxiliary protein) is essential for DNA replication and is involved in DNA excision and mismatch repair pathways. PCNA binds to the CDK inhibitor p21, the structure-specific endonucleases Fen1 and XPG, and DNA cytosine 5-methyltransferase (MCMT). PCNA is a potentially useful marker of cells with proliferative potential and for identifying the proliferation status of tumor tissue (i.e. relevant to prognosis). PCNA is a marker for cells in early G1 phase and S phase of the cell cycle. PCNA is found in the nucleus and is a cofactor of DNA polymerase delta, and acts as a homotrimer and helps increase the processing of leading strand synthesis during DNA replication. In response to DNA damage, PCNA is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for PCNA. Pseudogenes of PCNA have been described on chromosome 4 and on the X chromosome.

Immunogen :

Rat recombinant PCNA polypeptides

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-Dependent

Aliases :

ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; hypothetical protein LOC515499; MGC8367; Pcna; pcna protein; Pcna/cyclin; PCNAR; POL30; Proliferating cell nuclear antigen; wu:fa28e03; wu:fb36g03; YBR0811; YBR088C

more info or order :

Invitrogen product webpage