Claudin 5 Polyclonal Antibody | Invitrogen PA5-99415 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Claudin 5 Polyclonal Antibody

catalog :

PA5-99415

quantity :

100 uL

price :

US 494.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, bovine, pigs

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 4

Reference
Gong Z, Lao D, Wu Y, Li T, Lv S, Mo X, et al. Inhibiting PI3K/Akt-Signaling Pathway Improves Neurobehavior Changes in Anti-NMDAR Encephalitis Mice by Ameliorating Blood-Brain Barrier Disruption and Neuronal Damage. Cell Mol Neurobiol. 2023;43:3623-3637 pubmed publisher
Hammer S, Dorweiler T, McFarland D, Adu Agyeiwaah Y, Mast N, El Darzi N, et al. Cholesterol crystal formation is a unifying pathogenic mechanism in the development of diabetic retinopathy. Diabetologia. 2023;66:1705-1718 pubmed publisher
Bonato J, de Mattos B, Oliveira D, Milani H, Prickaerts J, de Oliveira R. Blood-Brain Barrier Rescue by Roflumilast After Transient Global Cerebral Ischemia in Rats. Neurotox Res. 2023;41:311-323 pubmed publisher
Zhu X, Ma T, Li Y, Zhang M, Zhao L, Liang J, et al. Fingolimod protects against neurovascular unit injury in a rat model of focal cerebral ischemia/reperfusion injury. Neural Regen Res. 2023;18:869-874 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Claudin 5 Polyclonal Antibody

Catalog # :

PA5-99415

Quantity :

100 uL

Price :

US 494.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Bovine, Human, Mouse, Non-human primate, Porcine, Rat

Applications :

Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2,000

Species :

Bovine, Human, Mouse, Non-human primate, Porcine, Rat

Isotype :

IgG

Storage :

-20 C

Description :

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc. Alternatively spliced transcript variants encoding different isoforms have been found.

Immunogen :

A synthesized peptide derived from human CLDN5(Accession O00501), corresponding to amino acid residues L181-V218.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2,000

Aliases :

AI854493; AWAL; BEC1; Brain endothelial cell clone 1 protein; claudin 5; claudin 5 (transmembrane protein deleted in velocardiofacial syndrome); claudin-5; claudin-5 protein; Cldn5; CPETRL1; lung-specific membrane protein; MBEC1; TMDVCF; TMVCF; Transmembrane protein deleted in VCFS; transmembrane protein deleted in velocardiofacial syndrome; Unknown (protein for MGC:138054)