Cytokeratin 14/16 Polyclonal Antibody | Invitrogen PA5-99310 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Cytokeratin 14/16 Polyclonal Antibody

catalog :

PA5-99310

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
De Vargas Roditi L, Jacobs A, Rueschoff J, Bankhead P, Chevrier S, Jackson H, et al. Single-cell proteomics defines the cellular heterogeneity of localized prostate cancer. Cell Rep Med. 2022;3:100604 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Cytokeratin 14/16 Polyclonal Antibody

Catalog # :

PA5-99310

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C

Description :

In Bowen's disease, the characteristic malignancy of the epidermis exhibits distinct expression patterns of Cytokeratin 14. Mutations in the gene encoding human Cytokeratin 14 lead to epidermolysis bullosa simplex, an inheritied skin disorder characterized by skin blistering due to basal keratinocyte fragility.Cytokeratin 16 is expressed in benign stratified squamous epithelium and squamous cell carcinoma of the head and neck, as well as luminal cells of mammary gland and sweat ducts. It is absent in noninvasive breast carcinomas and normal breast tissue. Mutations in the Cytokeratin 16 gene cause various diseases, including pachyonychia congenita type 1 (PC1), nonepidermolytic palmoplantar keratoderma (NEPPK) and unilateral palmoplantar verrucous nevus (UPVN).

Immunogen :

A synthesized peptide derived from human KRT14(Accession P02533), corresponding to amino acid residues M1-A36.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2,000

Aliases :

AI324768; AI626930; CK 14; CK 16; CK14; CK-14; CK16; CK-16; cytokeratin 14; cytokeratin 16; Cytokeratin14; cytokeratin-14; Cytokeratin16; Cytokeratin-16; EBS3; EBS4; epidermolysis bullosa simplex, Dowling-Meara, Koebner; FNEPPK; focal non-epidermolytic palmoplantar keratoderma; K14; K16; K1CP; Ka14; Ka16; keratin 14; keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner); keratin 14, type I; keratin 16; keratin 16, type I; keratin complex 1, acidic, gene 14; keratin complex 1, acidic, gene 16; keratin intermediate filament 16a; keratin intermediate filament 16b; keratin, type I cytoskeletal 14; Keratin, type I cytoskeletal 16; keratin-14; Keratin-16; Krt-1.14; Krt1-14; Krt1-16; Krt14; KRT16; KRT16A; NEPPK; NFJ; PC1; Type I keratin Ka14; type I keratin KA16