ZIC1/ZIC2/ZIC3 Polyclonal Antibody | Invitrogen PA5-99208 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ZIC1/ZIC2/ZIC3 Polyclonal Antibody

catalog :

PA5-99208

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

ZIC1/ZIC2/ZIC3 Polyclonal Antibody

Catalog # :

PA5-99208

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:3,000

Species :

Human, Mouse

Isotype :

IgG

Storage :

-20 C

Description :

Zic1 encodes a zinc finger protein expressed in the developing or matured central nervous system in a highly restricted manner. Zic is expressed in granule cells that make synaptic contact with Purkinje cells. Zic1 is a gene critical to cerebellar pattern formation. The expression of Zic genes is first detected at gastrulation and at neurulation, becoming restricted to the dorsal neural ectoderm and the dorsal paraxial mesoderm. The Zic1 gene has been mapped to chromosome 9 in mouse. The 5' flanking region of the Zic1 gene contains a region-specific enhancer determined to be essential in in-vivo and in-vitro deletion analysis. The temporal profile of mRNA expression differs for each of the Zic gene products. The Drosophila odd-paired gene is highly homologous to the Zic gene family. Zic2 and Zic3 are highly similar genes. Zic2 is essential for the formation of the brain and Zic-3 is important for right and left axis formation.

Immunogen :

A synthesized peptide derived from human ZIC1(Accession Q15915), corresponding to amino acid residues G328-R378.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:3,000

Aliases :

Bn; CRS6; GENA 29; heterotaxy 1; HPE5; HTX; HTX1; Ka; Ku; kumba; odd-paired homolog; RGD1561261; VACTERLX; Zic; Zic family member 1; Zic family member 1 (odd-paired homolog, Drosophila); Zic family member 2; Zic family member 2 (odd-paired homolog, Drosophila); Zic family member 3; Zic family member 3 (odd-paired homolog, Drosophila); zic protein member 1; Zic1; Zic2; Zic3; Zinc finger protein 201; zinc finger protein 203; Zinc finger protein of the cerebellum 1; zinc finger protein of the cerebellum 2; Zinc finger protein of the cerebellum 3; zinc finger protein ZIC 1; Zinc finger protein ZIC 2; zinc finger protein ZIC 3; ZNF201; ZNF203