PGRP-1a Polyclonal Antibody | Invitrogen PA5-98055 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PGRP-1a Polyclonal Antibody

catalog :

PA5-98055

quantity :

100 ug

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA

product information

Product Type :

Antibody

Product Name :

PGRP-1a Polyclonal Antibody

Catalog # :

PA5-98055

Quantity :

100 ug

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Protein G

Host :

Rabbit

Reactivity :

Human

Applications :

ELISA: Assay-Dependent, Western Blot: 1:500-1:5,000

Species :

Human

Isotype :

IgG

Storage :

-20 C or -80 C if preferred

Description :

Primary immune recognition is based on structures common among invading pathogens. Bacterial surface molecules, such as lipopolysaccharide (LPS) and peptidoglycan (PGN), are known to elicit immune reactions ranging from cytokine release to fever. Recently, a family of proteins called peptidoglycan recognition protein (PGRP) has been identified in mouse and human that binds to peptidoglycans expressed on Gram-positive bacteria. Peptidoglycan (PGN) is an essential cell wall component of virtually all bacteria (1, 2) and, thus, it is an excellent target for recognition by the eukaryotic innate immune system. The PGRPs (PGRP-L, PGRP-S, PGRP-Ia, and PGRP-I beta) define a new family of human pattern recognition molecules (3). PGRP-L is primarily expressed in the liver. Although liver is not considered a primary immune organ, liver participates in host defenses by producing acute phase proteins (by hepatocytes) in response to infections and by clearing microorganisms from blood (4). PGRP-1a mRNA is highly expressed in esophagus, tonsils and thymus and to lesser extent in the stomach, rectum, and brain.

Immunogen :

Recombinant Human Peptidoglycan recognition protein 3 protein (90-222AA)

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-Dependent, Western Blot: 1:500-1:5,000

Aliases :

Gm420; MGC149197; Peptidoglycan recognition protein 3; peptidoglycan recognition protein I alpha; peptidoglycan recognition protein I-alpha; Peptidoglycan recognition protein intermediate alpha; PGLYRP3; PGLYRPIalpha; PGRPIA; PGRP-Ialpha; PGRP-I-alpha