This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
LIN7A Polyclonal Antibody
catalog :
PA5-97927
quantity :
100 ug
price :
US 464.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA
product information
Product Type :
Antibody
Product Name :
LIN7A Polyclonal Antibody
Catalog # :
PA5-97927
Quantity :
100 ug
Price :
US 464.00
Clonality :
Polyclonal
Purity :
Protein G
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
ELISA: Assay-Dependent, Western Blot: 1:1,000-1:5,000
Species :
Human, Mouse
Isotype :
IgG
Storage :
-20 C or -80 C if preferred
Description :
Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
Immunogen :
Recombinant Human Protein lin-7 homolog A protein (1-233AA)
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-Dependent, Western Blot: 1:1,000-1:5,000
Aliases :
AI848705; hLin-7; lin 7 homolog a; LIN7; lin-7 homolog A (C. elegans); lin-7 homolog A, crumbs cell polarity complex component; Lin7a; lin-7A; lin-7-Ba; Mals1; MALS-1; mammalian LIN-7 1; mammalian lin-seven protein 1; mLin-7; protein lin-7 homolog A; Tax interaction protein 33; TIP-33; Veli; Veli1; veli-1; veli-1 protein; vertebrate homolog of C. elegans Lin-7 type 1; vertebrate LIN7 homolog 1; vertebrate lin-7 homolog 1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA