Factor XIII B Polyclonal Antibody | Invitrogen PA5-97725 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Factor XIII B Polyclonal Antibody

catalog :

PA5-97725

quantity :

100 ug

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA

product information

Product Type :

Antibody

Product Name :

Factor XIII B Polyclonal Antibody

Catalog # :

PA5-97725

Quantity :

100 ug

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Protein G

Host :

Rabbit

Reactivity :

Human

Applications :

ELISA: Assay-Dependent, Western Blot: 1:500-1:5,000

Species :

Human

Isotype :

IgG

Storage :

-20 C or -80 C if preferred

Description :

This gene encodes coagulation factor XIII B subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as a plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon activation by the cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion.

Immunogen :

Recombinant Human Coagulation factor XIII B chain protein (260-403AA)

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-Dependent, Western Blot: 1:500-1:5,000

Aliases :

coagulation factor XIII B chain; coagulation factor XIII, B polypeptide; F13B; Fibrin-stabilizing factor B subunit; FXIIIB; Protein-glutamine gamma-glutamyltransferase B chain; TGase; transglutaminase B chain