This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
APC5 Polyclonal Antibody
catalog :
PA5-96581
quantity :
100 uL
price :
US 464.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
APC5 Polyclonal Antibody
Catalog # :
PA5-96581
Quantity :
100 uL
Price :
US 464.00
Clonality :
Polyclonal
Purity :
Affinity Chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
ELISA: 1 ug/mL, Immunohistochemistry (Paraffin): 1:50-1:200, Immunoprecipitation: 0.5 ug-4 ug antibody for 200 ug-400 ug extracts of, Western Blot: 1:500-1:1,000
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome, a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein, compared to isoform a.
Immunogen :
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ANAPC5 (NP_0573212)
Format :
Liquid
Applications w/Dilutions :
ELISA: 1 ug/mL, Immunohistochemistry (Paraffin): 1:50-1:200, Immunoprecipitation: 0.5 ug-4 ug antibody for 200 ug-400 ug extracts of, Western Blot: 1:500-1:1,000
Aliases :
2510006G12Rik; AA408751; AA536819; AA986414; ANAPC5; anaphase promoting complex subunit 5; anaphase-promoting complex subunit 5; Anpc5; APC5; cyclosome subunit 5; MNCb-2778
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA