KHDRBS2 Polyclonal Antibody | Invitrogen PA5-96508 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

KHDRBS2 Polyclonal Antibody

catalog :

PA5-96508

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Sun R, Pan Y, Mu L, Ma Y, Shen H, Long Y. Development of a 3 RNA Binding Protein Signature for Predicting Prognosis and Treatment Response for Glioblastoma Multiforme. Front Genet. 2021;12:768930 pubmed publisher

product information

Product Type :

Antibody

Product Name :

KHDRBS2 Polyclonal Antibody

Catalog # :

PA5-96508

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Affinity Chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

ELISA: 1 ug/mL, Immunohistochemistry (Paraffin): 1:100-1:200, Western Blot: 1:500-1:1,000

Species :

Human, Mouse

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. Can regulate alternative splicing of NRXN1 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4) involved in neurexin selective targeting to postsynaptic partners. Regulates cell-type specific alternative splicing of NRXN1 at AS4 and acts synergistically with SAM68 in exon skipping. In contrast acts antagonistically with SAM68 in NRXN3 exon skipping at AS4. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. May function as an adapter protein for Src kinases during mitosis.

Immunogen :

A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human KHDRBS2 (NP_6899012)

Format :

Liquid

Applications w/Dilutions :

ELISA: 1 ug/mL, Immunohistochemistry (Paraffin): 1:100-1:200, Western Blot: 1:500-1:1,000

Aliases :

6330586C16Rik; hSLM-1; KH domain containing, RNA binding, signal transduction associated 2; KH domain-containing, RNA-binding, signal transduction-associated protein 2; KH RNA binding domain containing, signal transduction associated 2; Khdrbs2; mSLM-1; rSLM-1; Sam68-like mammalian protein 1; Slim1; SLM1; SLM-1