EED Polyclonal Antibody | Invitrogen PA5-92427 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

EED Polyclonal Antibody

catalog :

PA5-92427

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation

citations: 1

Reference
Lee M, Geitgey D, Hamilton J, Boss J, Scharer C, Spangle J, et al. Adipocyte-mediated epigenomic instability in human T-ALL cells is cytotoxic and phenocopied by epigenetic-modifying drugs. Front Cell Dev Biol. 2022;10:909557 pubmed publisher

product information

Product Type :

Antibody

Product Name :

EED Polyclonal Antibody

Catalog # :

PA5-92427

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Affinity Chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

ELISA: 1 ug/mL, Immunocytochemistry: 1:50-1:200, Immunoprecipitation: 0.5 ug-4 ug antibody for 200 ug-400 ug extracts of, Western Blot: 1:500-1:2,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

The EED protein (WAIT-1 or WD protein associated with integrin cytoplasmic tails-1), also called embryonic ectoderm development, is a member of the superfamily of WD-40 repeat proteins and widely conserved polycomb group (PcG) family of proteins. The polycomb group (PcG) is a large and evolutionarily conserved set of genes whose products act in multimeric complexes to modify histones, which are then thought to cause stable and heritable states of transcriptional repression. EED shuttles between the nucleus and the plasma membrane and can interact with the cytoplasmic tail of integrin Beta-7 subunit. EED exerted an antiviral activity at the late stage of HIV-1 replication.

Immunogen :

Recombinant fusion protein containing a sequence corresponding to amino acids 1-400 of human EED (NP_6945361)

Format :

Liquid

Applications w/Dilutions :

ELISA: 1 ug/mL, Immunocytochemistry: 1:50-1:200, Immunoprecipitation: 0.5 ug-4 ug antibody for 200 ug-400 ug extracts of, Western Blot: 1:500-1:2,000

Aliases :

EED; embryonic ectoderm development; Embryonic ectoderm development protein; ENSMUSG00000039373; HEED; l(7)5Rn; l7Rn5; lethal, Chr 7, Rinchik 5; lusk; Polycomb protein EED; WAIT1; WAIT-1; WD protein associating with integrin cytoplasmic tails 1