FBXO32 Polyclonal Antibody | Invitrogen PA5-91959 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

FBXO32 Polyclonal Antibody

catalog :

PA5-91959

quantity :

100 uL

price :

US 454.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunocytochemistry

citations: 3

Reference
Wang P, Kang S, Kim S, Park Y, Jung H. Monotropein Improves Dexamethasone-Induced Muscle Atrophy via the AKT/mTOR/FOXO3a Signaling Pathways. Nutrients. 2022;14: pubmed publisher
Wang P, Liu Y, Zhang T, Yin C, Kang S, Kim S, et al. Effects of Root Extract of Morinda officinalis in Mice with High-Fat-Diet/Streptozotocin-Induced Diabetes and C2C12 Myoblast Differentiation. ACS Omega. 2021;6:26959-26968 pubmed publisher
Weng S, Gao F, Wang J, Li X, Chu B, Wang J, et al. Improvement of muscular atrophy by AAV-SaCas9-mediated myostatin gene editing in aged mice. Cancer Gene Ther. 2020;: pubmed publisher

product information

Product Type :

Antibody

Product Name :

FBXO32 Polyclonal Antibody

Catalog # :

PA5-91959

Quantity :

100 uL

Price :

US 454.00

Clonality :

Polyclonal

Purity :

Affinity Chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

ELISA: 1 ug/mL, Immunocytochemistry: 1:50-1:200, Western Blot: 1:500-1:1,000

Species :

Human, Mouse

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs, which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing of this gene results in two transcript variants encoding two isoforms of different sizes.

Immunogen :

Recombinant fusion protein containing a sequence corresponding to amino acids 206-355 of human Fbx32/FBOX32 (NP_4781361)

Format :

Liquid

Applications w/Dilutions :

ELISA: 1 ug/mL, Immunocytochemistry: 1:50-1:200, Western Blot: 1:500-1:1,000

Aliases :

4833442G10Rik; AI430017; atrogin 1; atrogin1; atrogin-1; atrophy gene 1; F-box only protein 32; F-box protein 32; Fbx32; fbxo25; FBXO32; FLJ32424; Gm20361; MAFbx; MGC108443; MGC137646; MGC33610; Muscle atrophy F-box protein; similar to F-box only protein 32 isoform 1; zgc:56479