TXK Polyclonal Antibody | Invitrogen PA5-90043 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TXK Polyclonal Antibody

catalog :

PA5-90043

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

rat

application :

western blot, ELISA

product information

Product Type :

Antibody

Product Name :

TXK Polyclonal Antibody

Catalog # :

PA5-90043

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Affinity Chromatography

Host :

Rabbit

Reactivity :

Rat

Applications :

ELISA: 1 ug/mL, Western Blot: 1:500-1:2,000

Species :

Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

TXK, along with the close relatives BMS, ITK, and BTK, signal downstream of antigen receptors and other types of receptors. All members of the family contain SH3 and SH2 domains and, with the exception of Txk and Dsrc28C, also contain a pleckstrin homology (PH) and a Tec homology (TH) domain in their amino termini. Four alternatively spliced forms of Tec are found to be expressed broadly in cells of hematopoietic lineage and hepatocytes. The Emt gene product associates with CD28 and becomes activated subsequent to CD28 ligation. Btk is necessary for proper B cell development, and mutations in the gene encoding Btk have been associated with families suffering from X-linked agammaglobulinemia, also referred to as Bruton's disease. The Bmx protein shares a high degree of homology with Btk and seems to be expressed at highest levels in the heart. Txk expression is T cell-specific, while expression of the Drosophila Tec homolog, Dsrc28C, is developmentally regulated.

Immunogen :

Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human TXK (NP_0033192)

Format :

Liquid

Applications w/Dilutions :

ELISA: 1 ug/mL, Western Blot: 1:500-1:2,000

Aliases :

A130089B16Rik; BTKL; Protein-tyrosine kinase 4; PSCTK5; PTK4; PTK4 protein tyrosine kinase 4; PTK-RL-18; resting lymphocyte kinase; Rlk; TKL; TXK; TXK tyrosine kinase; tyrosine kinase; tyrosine-protein kinase TXK