This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
YAP1 Polyclonal Antibody
catalog :
PA5-87568
quantity :
100 uL
price :
US 470.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 1
Reference
Qin Y, Pei Z, Feng Z, Lin P, Wang S, Li Y, et al. Oncogenic Activation of YAP Signaling Sensitizes Ferroptosis of Hepatocellular Carcinoma via ALOXE3-Mediated Lipid Peroxidation Accumulation. Front Cell Dev Biol. 2021;9:751593 pubmed publisher
product information
Product Type :
Antibody
Product Name :
YAP1 Polyclonal Antibody
Catalog # :
PA5-87568
Quantity :
100 uL
Price :
US 470.00
Clonality :
Polyclonal
Purity :
Affinity Chromatography
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
ELISA: 1 ug/mL, Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Paraffin): 1:500-1:1,000, Immunoprecipitation: 0.5 ug-4 ug antibody for 200 ug-400 ug extracts of, Western Blot: 1:2,000-1:20,000
Species :
Human, Mouse
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
YAP (Yes-Associated Protein) is a founding member of the WW domain family of proteins, transcriptional co-activator and oncogene. Its gene is transcriptionally activated in squamous cell carcinoma cells. YAP can act both as a coactivator and corepressor and is the critical downstream regulatory target in the Hippo signaling pathway. The Hippo signaling pathway plays a pivotal role in organ size control and tumour suppression by restricting proliferation and promoting apoptosis. Also plays key roles in tissue tension, 3D tissue shape, cell proliferation, cell death, and cell migration. Mutations in the IRF5 gene results in coloboma.
Immunogen :
Recombinant fusion protein containing a sequence corresponding to amino acids 155-504 of human YAP1 (NP_0011236171)
Format :
Liquid
Applications w/Dilutions :
ELISA: 1 ug/mL, Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Paraffin): 1:500-1:1,000, Immunoprecipitation: 0.5 ug-4 ug antibody for 200 ug-400 ug extracts of, Western Blot: 1:2,000-1:20,000
Aliases :
65 kDa Yes-associated protein; AI325207; cb194; CH211-181P1.5-001; COB1; Protein yorkie homolog; sb:cb194; si:ch211-181p1.5; si:dkey-3b8.3; transcriptional coactivator YAP1; wu:fc18c04; yap; Yap1; YAP2; Yap65; Yes associated protein 1; Yes1 associated transcriptional regulator; yes-associated protein 1; yes-associated protein 2; yes-associated protein YAP65 homolog; yes-associated protein, 65 kDa; Yki; Yorkie; yorkie homolog; zgc:158380; zYAP
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA