XPA Polyclonal Antibody | Invitrogen PA5-86265 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

XPA Polyclonal Antibody

catalog :

PA5-86265

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Bariani M, Cui Y, Ali M, Bai T, Grimm S, Coarfa C, et al. TGFβ signaling links early life endocrine-disrupting chemicals exposure to suppression of nucleotide excision repair in rat myometrial stem cells. Cell Mol Life Sci. 2023;80:288 pubmed publisher

product information

Product Type :

Antibody

Product Name :

XPA Polyclonal Antibody

Catalog # :

PA5-86265

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry (Paraffin): 1:50-1:200

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

The XPA (xeroderma pigmentosumgroup A) protein specifically recognizes the UV-orchemically damaged DNA lesions, and triggers thenucleotide excision repair process. XPA binds to thereplication protein A (RPA) or the excision repaircross complementing 1 protein (ERCC 1). In the absence of nucleotide excision repair persisting (unrepaired) DNA lesions (adducts) may lead to the accumulation of gene mutations and ultimately to cancer. Xeroderma pigmentosum patients have a >2000 fold increased risk to develop skin cancer atsun-exposed areas.

Immunogen :

Synthetic peptide, corresponding to amino acids 215-260 of Human XPA.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:50-1:200

Aliases :

AI573865; DNA repair protein complementing XP-A cells; DNA repair protein complementing XP-A cells homolog; excision repair-controlling; mutant xeroderma pigmentosum complementation group A; xeroderma pigmentosum group A-complementing protein; Xeroderma pigmentosum group A-complementing protein homolog; xeroderma pigmentosum, complementation group A; XP1; XPA; XPA, DNA damage recognition and repair factor; Xpac