CD34 Polyclonal Antibody | Invitrogen PA5-85917 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD34 Polyclonal Antibody

catalog :

PA5-85917

quantity :

100 uL

price :

US 460.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 8

Reference
Xu L, Zhang L, Xiang Y, Zhang X. Therapeutic role of adipose-derived mesenchymal stem cells-derived extracellular vesicles in rats with obstructive sleep apnea hypopnea syndrome. Regen Ther. 2023;22:210-223 pubmed publisher
Zhou M, Hui J, Gao L, Liang J, Wang C, Xu J. Extracellular vesicles from bone marrow mesenchymal stem cells alleviate acute rejection injury after liver transplantation by carrying miR-22-3p and inducing M2 polarization of Kupffer cells. J Gene Med. 2023;25:e3497 pubmed publisher
Yin G, Wang J, Zhong Y, Wu W. Propofol suppresses adipose-derived stem cell progression via PI3K/AKT-Wnt signaling pathway. BMC Anesthesiol. 2022;22:65 pubmed publisher
Chang P, Li S, Sun Q, Guo K, Wang H, Li S, et al. Fully Reduced HMGB1-Containing Peptide-Based Polyurethane Scaffold with Minimal Functional Unit of Skin (MFUS) Enhances Large and Deep Wounded Skin Healing. Macromol Biosci. 2022;22:e2100403 pubmed publisher
Rocha L, Barbosa G, Pimentel Neto J, Jacob C, Knudsen A, Watanabe I, et al. Aquatic Training after Joint Immobilization in Rats Promotes Adaptations in Myotendinous Junctions. Int J Mol Sci. 2021;22: pubmed publisher
Zhu J, Fu Q, Shao J, Peng J, Qian Q, Zhou Y, et al. Over-expression of MEG3 promotes differentiation of bone marrow mesenchymal stem cells into chondrocytes by regulating miR-129-5p/RUNX1 axis. Cell Cycle. 2021;20:96-111 pubmed publisher
Pimentel Neto J, Rocha L, Barbosa G, Jacob C, Krause Neto W, Watanabe I, et al. Myotendinous junction adaptations to ladder-based resistance training: identification of a new telocyte niche. Sci Rep. 2020;10:14124 pubmed publisher
Zou L, Ma X, Lin S, Wu B, Chen Y, Peng C. Bone marrow mesenchymal stem cell-derived exosomes protect against myocardial infarction by promoting autophagy. Exp Ther Med. 2019;18:2574-2582 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD34 Polyclonal Antibody

Catalog # :

PA5-85917

Quantity :

100 uL

Price :

US 460.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Flow Cytometry: 1:1,000, Immunocytochemistry: 1:250, Immunohistochemistry (Paraffin): 1:2,000-1:3,000, Western Blot: 1:1,000-1:2,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

CD34 is a highly glycosylated monomeric with a molecular weight range of 111-115 kDa surface protein that is present on many stem cell populations. CD34 is a stem cell marker although its expression on human hematopoietic stem cells is reversible. CD34 may serve as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions. CD34 is possibly an adhesion molecule with a putative role for mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Further, CD34 could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is thought to have a role in presenting carbohydrate ligands to selectins. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C suggesting a putative role in signal transduction. Diseases associated with CD34 dysfunction include dermatofibrosarcoma and neurofibroma.

Immunogen :

Synthetic peptide within Human CD34 aa 336-385

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:1,000, Immunocytochemistry: 1:250, Immunohistochemistry (Paraffin): 1:2,000-1:3,000, Western Blot: 1:1,000-1:2,000

Aliases :

(E3-independent) E2 ubiquitin-conjugating enzyme R1; AU040960; CD34; CD34 antigen; CD34 molecule; CDC34; cell division cycle 34; cell division cycle 34 homolog; cluster designation 34; cluster of differentiation antigen 34; E2 ubiquitin-conjugating enzyme R1; E2-CDC34; hematopoietic progenitor cell antigen CD34; hematopoietic progenitor cell marker CD34; Mucosialin; RP11-328D5.2; sialomucin protein; type 1 transmembrane protein; UBC3; UBCH3; UBE2R1; ubiquitin carrier protein; ubiquitin conjugating enzyme E2 R1; ubiquitin-conjugating enzyme E2 R1; Ubiquitin-conjugating enzyme E2-32 kDa complementing; ubiquitin-conjugating enzyme E2-CDC34; Ubiquitin-protein ligase R1