PHLDA1 Polyclonal Antibody | Invitrogen PA5-84598 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PHLDA1 Polyclonal Antibody

catalog :

PA5-84598

quantity :

100 uL

price :

US 474.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

immunocytochemistry

product information

Product Type :

Antibody

Product Name :

PHLDA1 Polyclonal Antibody

Catalog # :

PA5-84598

Quantity :

100 uL

Price :

US 474.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Immunocytochemistry: 0.25-2 ug/mL

Species :

Human

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Cytotoxic T lymphocyte (CTL)-mediated cytotoxicity constitutes an important component of specific effector mechanisms in immunosurveillance against virus-infected or -transformed cells. Two mechanisms appear to account for this activity, one of which is the perforin-based process. Independently, a FAS-based mechanism involves the transducing molecule FAS (APO-1) and its ligand (FAS-L). The human FAS (APO-1) protein is a 48 kDa cell surface glycoprotein that belongs to a family of receptors that includes CD40, nerve growth factor receptors and tumor necrosis factor receptors. The FAS antigen is expressed on a broad range of lymphoid cell lines, and is expressed at high levels in T cells subsequent to crosslinking of the T cell receptor (TCR). A previously undescribed protein, TDAG51, restores activation- induced apoptosis in cells that have lost the ability to display Fas in response to activation.

Immunogen :

Recombinant protein corresponding to Human PHLDA1. Recombinant protein control fragment (Product # RP-107243 ).

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 0.25-2 ug/mL

Aliases :

apoptosis-associated nuclear protein; DT1P1B11; PHLDA1; PHRIP; pleckstrin homology like domain family A member 1; pleckstrin homology-like domain family A member 1; pleckstrin homology-like domain, family A, member 1; PQR protein; PQ-rich protein; proline- and glutamine-rich protein; Proline- and histidine-rich protein; proline-histidine rich protein; T-cell death associated; T-cell death-associated gene 51 protein; Tdag; TDAG51