This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
MUC5B Polyclonal Antibody
catalog :
PA5-82342
quantity :
100 uL
price :
US 514.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 3
Reference
Prescott R, Pankow A, de Vries M, Crosse K, Patel R, Alu M, et al. A comparative study of in vitro air-liquid interface culture models of the human airway epithelium evaluating cellular heterogeneity and gene expression at single cell resolution. Respir Res. 2023;24:213 pubmed publisher
Albers S, Allen E, Bharti N, Davyt M, Joshi D, Perez Garcia C, et al. Engineered tRNAs suppress nonsense mutations in cells and in vivo. Nature. 2023;618:842-848 pubmed publisher
Groiss S, Somvilla I, Daxb xf6 ck C, Fuchs J, Lang Olip I, Stiegler P, et al. Quantification of increased MUC5AC expression in airway mucus of smoker using an automated image-based approach. Microsc Res Tech. 2022;85:5-18 pubmed publisher
product information
Product Type :
Antibody
Product Name :
MUC5B Polyclonal Antibody
Catalog # :
PA5-82342
Quantity :
100 uL
Price :
US 514.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human
Applications :
Immunocytochemistry: 0.25-2 ug/mL, Immunohistochemistry (Paraffin): 1:500-1:1,000
Species :
Human
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
Mucins (MUCs) are heavily glycosylated glycoproteins that are synthesized either as membrane-bound or secreted proteins. Mucins are noteworthy because they have an aberrant expression profile in various malignancies. Mucins normally play a protective role for epithelial tissues and are expressed in the gastrointestinal, respiratory, and genito-urinary tracts. Mucins may also be involved in the renewal and differentiation of the epithelium, and the modulation of cell adhesion and cell signaling. MUC5B is thought to play a vital role in maintaining oral health, and may also be involved in respiratory and oral disease.2 MUC5B expression has been studied in gastric carcinoma as well as chronic obstructive pulmonary disease.
Immunogen :
Recombinant protein corresponding to Human MUC5B. Recombinant protein control fragment (Product # RP-88563 ).
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 0.25-2 ug/mL, Immunohistochemistry (Paraffin): 1:500-1:1,000
Aliases :
Cervical mucin; cervical mucin MUC5B; high molecular weight salivary mucin MG1; MG1; MUC5; MUC5B; MUC-5B; MUC9; mucin 5, subtype B, tracheobronchial; mucin 5B, oligomeric mucus/gel-forming; Mucin-5 subtype B, tracheobronchial; Mucin-5B; sublingual gland mucin
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA