This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
ECD Polyclonal Antibody
catalog :
PA5-81542
quantity :
100 uL
price :
US 319.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
mouse
application :
immunohistochemistry, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
ECD Polyclonal Antibody
Catalog # :
PA5-81542
Quantity :
100 uL
Price :
US 319.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography, Protein A
Host :
Rabbit
Reactivity :
Mouse
Applications :
Immunohistochemistry (Paraffin): 1:200-1:1,000
Species :
Mouse
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
Regulator of p53/TP53 stability and function. Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP (PubMed:16849563, PubMed:23880345). May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes (PubMed:19919181, PubMed:9928932). Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins (PubMed:19640839). The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex (PubMed:26711270). May play a role in regulation of pre-mRNA splicing (PubMed:24722212). [UniProt]
Immunogen :
A synthetic peptide corresponding to the center region of the Mouse ECD/Ecdysoneless homolog
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:200-1:1,000
Aliases :
5730461K03Rik; Ecd; ecdysoneless cell cycle regulator; ecdysoneless homolog; ecdysoneless homolog (Drosophila); GCR2; HSGT1; Human suppressor of GCR two; protein ecdysoneless homolog; protein SGT1; protein SGT1 homolog; SGT1; SGT1 protein; suppressor of GCR2; suppressor of S. cerevisiae gcr2
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA