SSX2 Polyclonal Antibody | Invitrogen PA5-80074 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SSX2 Polyclonal Antibody

catalog :

PA5-80074

quantity :

100 ug

price :

US 404.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 5s6b	Murata K, Nakatsugawa M, Rahman M, Nguyen L, Millar D, Mulder D, et al. Landscape mapping of shared antigenic epitopes and their cognate TCRs of tumor-infiltrating T lymphocytes in melanoma. elife. 2020;9: pubmed publisher

product information

Product Type :

Antibody

Product Name :

SSX2 Polyclonal Antibody

Catalog # :

PA5-80074

Quantity :

100 ug

Price :

US 404.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 0.5-1 ug/mL, Western Blot: 0.1-0.5 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C

Description :

SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human SSX2 (157-184aa NREAQEKEERRGTAHRWSSQNTHNIGRF).

Format :

Lyophilized

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 0.5-1 ug/mL, Western Blot: 0.1-0.5 ug/mL

Aliases :

cancer/testis antigen 5.2; cancer/testis antigen family 5, member 2a; CT5.2; CT5.2A; CT52; HD21; HOM-MEL-40; LOC103690782; MGC119055; MGC15364; MGC3884; Protein SSX2; putative protein SSX10; sarcoma, synovial, X-chromosome-related 2; SSX; SSX family member 2; SSX2; SSX2A; SSX2B; Synovial sarcoma, X breakpoint 2; synovial sarcoma, X breakpoint 2B; tumor antigen HOM-MEL-40

more info or order :

Invitrogen product webpage