RUNX1T1 Polyclonal Antibody | Invitrogen PA5-79943 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RUNX1T1 Polyclonal Antibody

catalog :

PA5-79943

quantity :

100 ug

price :

US 410.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 1

Reference
Jiang N, Wang Z, Guo X, Peng Z, He Y, Wang Q, et al. Hepatic Runx1t1 improves body fat index after endurance exercise in obese mice. Sci Rep. 2023;13:19427 pubmed publisher

product information

Product Type :

Antibody

Product Name :

RUNX1T1 Polyclonal Antibody

Catalog # :

PA5-79943

Quantity :

100 ug

Price :

US 410.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

ELISA: 0.1-0.5 ug/mL, Flow Cytometry: 1-3 ug/1x10^6 cells, Immunocytochemistry: 2 ug/mL, Immunohistochemistry (Frozen): 0.5-1 ug/mL, Immunohistochemistry (Paraffin): 0.5-1 ug/mL, Western Blot: 0.1-0.5 ug/mL

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C

Description :

RUNX1T1 is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Several transcript variants encoding multiple isoforms have been found for this gene.

Immunogen :

E. coli-derived human RUNX1T1/ETO recombinant protein (Position: T335-D510).

Format :

Lyophilized

Applications w/Dilutions :

Aliases :

acute myelogenous leukemia 1 translocation 1 protein; acute myelogenous leukemia 1 translocation 1, cyclin-D related; AML1-MTG8; AML1T1; Cbfa2t1; CBFA2T1 identified gene homolog; CBFA2T1 isoform r1t1-11a61; CBFA2T1 isoform r1t1-11a62; CBFA2T1 isoform r1t1-11a63; CBFA2T1 isoform r1t1-11a64; CBFA2T1 isoform r1t1-11a65; CBFA2T1 isoform r1t1-7a47; CBFA2T1 isoform r1t1-7a48; CBFA2T1 isoform r1t1-7a49; CBFA2T1 isoform r1t1-7a50; CBFA2T1 isoform r1t1-7a51; CBFA2T1 isoform r1t1-7a52; CBFA2T1 isoform r1t1-7d53; CBFA2T1 isoform r1t1-7d54; CBFA2T1 isoform r1t1-7d55; CBFA2T1 isoform r1t1-7d56; CBFA2T1 isoform r1t1-8a57; CBFA2T1 isoform r1t1-8a58; CBFA2T1 isoform r1t1-8a59; CBFA2T1 isoform r1t1-8a60; Cbfa2t1h; CDR; core-binding factor, runt domain, alpha subunit 2, translocated to, 1; core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related; cyclin D-related; Cyclin-D-related protein; Eight twenty one protein; ETO; LOW QUALITY PROTEIN: protein CBFA2T1; MGC2796; MTG8; MTG8b; myeloid translocation gene on 8q22; protein CBFA2T1; protein CBFA2T1; LOW QUALITY PROTEIN: protein CBFA2T1; protein CBFA2T1-like; Protein ETO; Protein MTG8; runt related transcription factor 1; translocated to, 1 (cyclin D related); runt-related transcription factor 1; translocated to, 1 (cyclin D-related); RUNX1 partner transcriptional co-repressor 1; RUNX1 translocation partner 1; Runx1t1; si:ch211-232j17.1; translocated to, 1; wu:fi14b07; zgc:154044; zinc finger MYND domain-containing protein 2; ZMYND2