This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD68 Polyclonal Antibody
catalog :
PA5-78996
quantity :
100 ug
price :
US 410.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
mouse, rat
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 8
Reference
Yang A, Kim Y, Yan X, Abe H, Aslam M, Park K, et al. Fibroblast Activation Protein Activates Macrophages and Promotes Parenchymal Liver Inflammation and Fibrosis. Cell Mol Gastroenterol Hepatol. 2023;15:841-867 pubmed publisher
Remic T, Sersa G, Levpuscek K, Lampreht Tratar U, Ursic Valentinuzzi K, C xf6 r A, et al. Tumor cell-based vaccine contributes to local tumor irradiation by eliciting a tumor model-dependent systemic immune response. Front Immunol. 2022;13:974912 pubmed publisher
Ben X, Wang Y, Zheng H, Li D, Ren R, Ni P, et al. Construction of Exosomes that Overexpress CD47 and Evaluation of Their Immune Escape. Front Bioeng Biotechnol. 2022;10:936951 pubmed publisher
Ding X, Zhou J, Zhao L, Chen M, Wang S, Zhang M, et al. Intestinal Flora Composition Determines Microglia Activation and Improves Epileptic Episode Progress. Front Cell Infect Microbiol. 2022;12:835217 pubmed publisher
Chun C, Qi X, Wang F, Madrid K, Saldarriaga L, Fisch M, et al. Nicotine Exacerbates TAAD Formation Induced by Smooth Muscle-Specific Deletion of the TGF-β Receptor 2. J Immunol Res. 2021;2021:6880036 pubmed publisher
Zhang H, Lin S, McElroy C, Wang B, Jin D, Uteshev V, et al. Circulating Pro-Inflammatory Exosomes Worsen Stroke Outcomes in Aging. Circ Res. 2021;129:e121-e140 pubmed publisher
Qi X, Wang F, Chun C, Saldarriaga L, Jiang Z, Pruitt E, et al. A validated mouse model capable of recapitulating the protective effects of female sex hormones on ascending aortic aneurysms and dissections (AADs). Physiol Rep. 2020;8:e14631 pubmed publisher
Xu J, Moon H, Xu J, Lim J, Fischer T, McNally H, et al. One-Step Large-Scale Nanotexturing of Nonplanar PTFE Surfaces to Induce Bactericidal and Anti-inflammatory Properties. ACS Appl Mater Interfaces. 2020;12:26893-26904 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CD68 Polyclonal Antibody
Catalog # :
PA5-78996
Quantity :
100 ug
Price :
US 410.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Mouse, Rat
Applications :
Flow Cytometry: 1-3 ug/1x10^6 cells, Immunohistochemistry (Paraffin): 2-5 ug/mL, Immunohistochemistry: 5 ug/mL, Western Blot: 0.1-0.5 ug/mL
Species :
Mouse, Rat
Isotype :
IgG
Storage :
-20 C
Description :
CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.
Immunogen :
A synthetic peptide corresponding to a sequence in the middle region of mouse CD68 (312-326aa AFCITRRRQSTYQPL).
Format :
Lyophilized
Applications w/Dilutions :
Flow Cytometry: 1-3 ug/1x10^6 cells, Immunohistochemistry (Paraffin): 2-5 ug/mL, Immunohistochemistry: 5 ug/mL, Western Blot: 0.1-0.5 ug/mL
Aliases :
CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA