Caspase 3 p17 Polyclonal Antibody | Invitrogen PA5-78921 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Caspase 3 p17 Polyclonal Antibody

catalog :

PA5-78921

quantity :

100 ug

price :

US 404.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 2

Reference
Li Z, Chen L, Zhang D, Huang X, Yang J, Li W, et al. Intranasal 15d-PGJ2 inhibits the growth of rat lactotroph pituitary neuroendocrine tumors by inducing PPARγ-dependent apoptotic and autophagic cell death. Front Neurosci. 2023;17:1109675 pubmed publisher
El Boshy M, Refaat B, Almaimani R, Abdelghany A, Ahmad J, Idris S, et al. Vitamin D3 and calcium cosupplementation alleviates cadmium hepatotoxicity in the rat: Enhanced antioxidative and anti-inflammatory actions by remodeling cellular calcium pathways. J Biochem Mol Toxicol. 2020;34:e22440 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Caspase 3 p17 Polyclonal Antibody

Catalog # :

PA5-78921

Quantity :

100 ug

Price :

US 404.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Mouse, Rat

Applications :

Immunohistochemistry (Paraffin): 0.5-1 ug/mL, Western Blot: 0.1-0.5 ug/mL

Species :

Mouse, Rat

Isotype :

IgG

Storage :

-20 C

Description :

CASP3 (Caspase3 Apoptosis-Related Cysteine Protease), also known as YAMA, CPP32 or APOPAIN, is a caspase protein that interacts with caspase 8 and caspase 9. It is encoded by the CASP3 gene. The CASP3 protein is a member of the cysteine-aspartic acid protease (caspase) family. Tiso et al. (1996) used radiation hybrid mapping to localize the CPP32 gene to human chromosome 4q33-q35.1. Fernandes-Alnemri et al. (1994) found that overexpression of CPP32 in insect cells induced apoptosis. Coexpression of the 2 CPP32 subunits in insect cells also resulted in apoptosis. Tewari et al. (1995) showed that purified human ICE cleaved the Yama proenzyme into a proteolytically active form and that activated Yama cleaved PARP into the 85-kD apoptotic form.

Immunogen :

A synthetic peptide corresponding to a sequence at the N-terminus of mouse Caspase-3 (P17) (67-81aa TDVDAANLRETFMGL).

Format :

Lyophilized

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 0.5-1 ug/mL, Western Blot: 0.1-0.5 ug/mL

Aliases :

A830040C14Rik; AC-3; Apopain; Casp3; CASP-3; caspase 3; Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis related cysteine protease; Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease); caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; CC3; Cleaved Caspase 3; Cpp32; CPP-32; CPP32beta; cysteine protease CPP32; IRP; LICE; mldy; protein Yama; SCA-1; SREBP cleavage activity 1; Yama; yama protein