Hemoglobin gamma A Polyclonal Antibody | Invitrogen PA5-77998 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Hemoglobin gamma A Polyclonal Antibody

catalog :

PA5-77998

quantity :

100 uL

price :

US 514.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

citations: 1

Reference
Simbula M, Manchinu M, Mingoia M, Pala M, Asunis I, Caria C, et al. miR-365-3p mediates BCL11A and SOX6 erythroid-specific coregulation: A new player in HbF activation. Mol Ther Nucleic Acids. 2023;34:102025 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Hemoglobin gamma A Polyclonal Antibody

Catalog # :

PA5-77998

Quantity :

100 uL

Price :

US 514.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Western Blot: 1:500-1:3,000

Species :

Human

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon - gamma-G - gamma-A - delta - beta-3'.

Immunogen :

Full length human Hemoglobin gamma A Recombinant protein.

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:500-1:3,000

Aliases :

A-gamma globin; epsilon 3 globin; gamma A hemoglobin; gamma globin; gamma-1-globin; Hb F Agamma; Hbb-y; Hbe1; Hbg1; HBGA; HBGR; HBG-T2; Hemoglobin gamma-1 chain; hemoglobin gamma-a chain; hemoglobin subunit gamma 1; hemoglobin subunit gamma-1; hemoglobin Y beta-like embryonic chain; hemoglobin Y, beta-like embryonic chain; hemoglobin, epsilon 1; hemoglobin, gamma A; hemoglobin, gamma, regulator of; HSGGL1; PRO2979