Caspase 3 Polyclonal Antibody | Invitrogen PA5-77887 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Caspase 3 Polyclonal Antibody

catalog :

PA5-77887

quantity :

100 uL

price :

US 470.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 12

Reference
Esp xed rito Santo S, da Silva T, Cogliati B, Barbisan L, Romualdo G. Panx1 knockout promotes preneoplastic aberrant crypt foci development in a chemically induced model of mouse colon carcinogenesis. Int J Exp Pathol. 2023;104:304-312 pubmed publisher
Ta x15f tan Bal T, Akaras N, Demir x, Ugan R. Protective effect of astaxanthin and metformin in the liver of rats in which the polycystic ovary syndrome model was formed by giving letrozole. Iran J Basic Med Sci. 2023;26:688-694 pubmed publisher
Kim H, Kang B, Park S, Park H, Kim C, Lee H, et al. Forkhead box protein D2 suppresses colorectal cancer by reprogramming enhancer interactions. Nucleic Acids Res. 2023;51:6143-6155 pubmed publisher
Singh R, Zahra W, Singh S, Birla H, Rathore A, Keshri P, et al. Oleuropein confers neuroprotection against rotenone-induced model of Parkinson's disease via BDNF/CREB/Akt pathway. Sci Rep. 2023;13:2452 pubmed publisher
Huang Q, Yang Y, Zhao T, Chen Q, Liu M, Ji S, et al. Passively-targeted mitochondrial tungsten-based nanodots for efficient acute kidney injury treatment. Bioact Mater. 2023;21:381-393 pubmed publisher
Liu P, Li X, Liu J, Zhang H, You Z, Zhang J. Cacna2d2 inhibits axonal regeneration following surgical decompression in a rat model of cervical spondylotic myelopathy. BMC Neurosci. 2022;23:42 pubmed publisher
Assar D, Mokhbatly A, Ghazy E, Elbialy Z, Gaber A, Hassan A, et al. Silver nanoparticles induced hepatoxicity via the apoptotic/antiapoptotic pathway with activation of TGFβ-1 and α-SMA triggered liver fibrosis in Sprague Dawley rats. Environ Sci Pollut Res Int. 2022;29:80448-80465 pubmed publisher
Sánchez Ramos C, Bonnin Arias C, Bl xe1 zquez S xe1 nchez V, Aguirre Vilacoro V, Cobo T, Garc xed a Suarez O, et al. Retinal Protection from LED-Backlit Screen Lights by Short Wavelength Absorption Filters. Cells. 2021;10: pubmed publisher
Sherif I, Al Shaalan N, Sabry D. Neuroprotective Potential of Bone Marrow-Derived Mesenchymal Stem Cells Following Chemotherapy. Biomedicines. 2021;9: pubmed publisher
Matuq Al Yasi H, El Shazly S, Ahmed E, Hasan Alamer K, Hessini K, Attia H, et al. Protective Effects of Taif Rosewater Against Testicular Impairment Induced By Lead Intoxication In Rats. Andrologia. 2021;53:e14045 pubmed publisher
Golosova D, Palygin O, Bohovyk R, Klemens C, Levchenko V, Spires D, et al. Role of opioid signaling in kidney damage during the development of salt-induced hypertension. Life Sci Alliance. 2020;3: pubmed publisher
Haddad Y, Said R, Kamel R, Morsy E, El Demerdash E. Phytoestrogen genistein hinders ovarian oxidative damage and apoptotic cell death-induced by ionizing radiation: co-operative role of ER-β, TGF-β, and FOXL-2. Sci Rep. 2020;10:13551 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Caspase 3 Polyclonal Antibody

Catalog # :

PA5-77887

Quantity :

100 uL

Price :

US 470.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Frozen): 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Immunoprecipitation: 1:100-1:500, Western Blot: 1:500-1:10,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

Immunogen :

Recombinant protein encompassing a sequence within the center region of human Caspase 3. The exact sequence is proprietary.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Frozen): 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Immunoprecipitation: 1:100-1:500, Western Blot: 1:500-1:10,000

Aliases :

A830040C14Rik; AC-3; Apopain; Apopain precursor; Casp3; CASP-3; caspase 3; Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis related cysteine protease; Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; Caspase3; caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; Caspase-3-like protein; CC3; Cpp32; CPP-32; CPP32B; CPP32beta; cysteine protease CPP32; cysteine protease; CPP32; apopain; ICE3; IRP; LICE; mldy; PARP cleavage protease; procaspase3; protein Yama; SCA-1; SREBP cleavage activity 1; Yama; yama protein