NFS1 Polyclonal Antibody | Invitrogen PA5-76984 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

NFS1 Polyclonal Antibody

catalog :

PA5-76984

quantity :

100 uL

price :

US 481.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Hackett P, Jia X, Li L, Ward D. Posttranslational regulation of mitochondrial frataxin and identification of compounds that increase frataxin levels in Friedreich's ataxia. J Biol Chem. 2022;298:101982 pubmed publisher

product information

Product Type :

Antibody

Product Name :

NFS1 Polyclonal Antibody

Catalog # :

PA5-76984

Quantity :

100 uL

Price :

US 481.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

NFS1 (nitrogen fixation 1), also known as NIFS or IscS (cysteine desulfurase), is a member of the class V pyridoxal-phosphate-dependent aminotransferase family. It localizes to the cytoplasm or mitochondrion depending on which form is generated based on cytosolic pH. Highest expression levels of NFS1 are found in heart and skeletal muscle. Lower levels of expression are also found in liver, brain and pancreas. NFS1 is responsible for catalyzing the removal of sulfur from cysteine to form alanine, thereby supplying the inorganic sulfur for iron-sulfur (Fe-S) clusters. Fe-S clusters function as essential cofactors in a wide variety of events, including facilitation of electron transfer processes in oxidative phosphorylation, catalysis of enzymatic reactions in aconitase and dehydratases and maintenance of structural integrity in the DNA repair enzyme endonuclease III.

Immunogen :

Recombinant full length Human NFS1.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2,000

Aliases :

AA987187; cysteine desulfurase, mitochondrial; Cysteine desulfurase, mitochondrial-like protein; HUSSY-08; IscS; LOW QUALITY PROTEIN: cysteine desulfurase, mitochondrial; m-Nfs1; m-Nfsl; Nfs1; NFS1 cysteine desulfurase; NFS1 nitrogen fixation 1 homolog; NFS1 nitrogen fixation 1 homolog (S. cerevisiae); NFS1, cysteine desulfurase; Nifs; nifS-like (sic); nitrogen fixation 1 (S. cerevisiae, homolog); nitrogen fixation gene 1; nitrogen fixation gene 1 (S. cerevisiae); nitrogen fixation gene, yeast homolog 1; nitrogen-fixing bacteria S-like protein