MMRN1 Polyclonal Antibody | Invitrogen PA5-76977 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MMRN1 Polyclonal Antibody

catalog :

PA5-76977

quantity :

100 uL

price :

US 481.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry

product information

Product Type :

Antibody

Product Name :

MMRN1 Polyclonal Antibody

Catalog # :

PA5-76977

Quantity :

100 uL

Price :

US 481.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 1:50-1:100, Western Blot: 1:500-1:2,000

Species :

Human, Mouse

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Multimerin-1, also known as MMRN1, EMILIN-4 or ECM (endothelial cell multimerin), is a 1,228 amino acid secreted protein that contains one C1q domain, one EMI domain and one EGF-like domain. Synthesized in megakaryocytes and endothelial cells and present in liver, lung and placenta, Multimerin-1 exists as a multimeric structure composed of varying disulfide-linked multimers and functions as a carrier protein for platelet factors (specifically platelet factor V), playing a role in the stabilization and storage of factor V in platelets. In addition, Multimerin-1 acts as a ligand for select Integrins and may participate in extracellular matrix adhesion. Defects in the gene encoding Multimerin-1 that lead to Multimerin-1 deficiency are associated with autosomal dominant bleeding disorders due to platelet factor malfunction. Multiple isoforms of Multimerin-1 exist due to alternative splicing events.

Immunogen :

Recombinant fusion protein containing a sequence corresponding to amino acids 1083-1228 of human MMRN1.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:50-1:100, Western Blot: 1:500-1:2,000

Aliases :

155 kDa platelet multimerin; 4921530G03Rik; ECM; Elastin microfibril interface located protein 4; elastin microfibril interfacer 4; EMILIN4; EMILIN-4; Endothelial cell multimerin; glycoprotein Ia*; GPIa*; MMRN; mmrn1; multimerin 1; multimerin-1; p155; p-155; Platelet glycoprotein Ia*