LECT1 Polyclonal Antibody | Invitrogen PA5-76974 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

LECT1 Polyclonal Antibody

catalog :

PA5-76974

quantity :

100 uL

price :

US 470.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry

citations: 2

Reference
Qian J, Zhu R, Yan R, Long X, Guo F. Isolation of mouse ovarian follicles for single-cell RNA-seq and in vitro culture. STAR Protoc. 2022;3:101537 pubmed publisher
Long X, Yang Q, Qian J, Yao H, Yan R, Cheng X, et al. Obesity modulates cell-cell interactions during ovarian folliculogenesis. iScience. 2022;25:103627 pubmed publisher

product information

Product Type :

Antibody

Product Name :

LECT1 Polyclonal Antibody

Catalog # :

PA5-76974

Quantity :

100 uL

Price :

US 470.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 1:50-1:100, Western Blot: 1:500-1:2,000

Species :

Human, Mouse

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

ChM-1 is a cartilage-specific matrix glycoprotein that stimulates the growth of chondrocytes. ChM-1 inhibits angiogenesis by disrupting the tube formation of endothelial cells and thus is responsible for the avascular nature of cartilage. ChM-1 is strongly expressed by the proliferating and hypertrophic zones in the epiphyseal plate of long bones. ChM-1 accumulates in the interterritorial matrix around the lacunae. During development, downregulation of ChM-1 permits angiogenesis and ultimately bone formation on the cartilage template. ChM-1 expression is downregulated in the presence of several growth factors including TGF 2, FGF2 and PTHLH. ChM-1 expression may also play a role in the hypovascularity and chondroid formation of pleomorphic adenomas. The gene encoding human ChM-1 maps to chromosome 13q14-q21.

Immunogen :

Recombinant full length Human LECT1.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:50-1:100, Western Blot: 1:500-1:2,000

Aliases :

BRICD3; BRICHOS domain containing 3; CHM1; Chm-1; Chmi; CHM-I; Chondromodulin; Chondromodulin 1; chondromodulin I; chondromodulin-1; Chondromodulin-I; Chondrosurfactant protein; CH-SP; Cnmd; LECT1; leukocyte cell derived chemotaxin 1; leukocyte cell-derived chemotaxin 1; multiple myeloma tumor suppressor 1; MYETS1