Ubiquitin C Polyclonal Antibody | Invitrogen PA5-76144 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Ubiquitin C Polyclonal Antibody

catalog :

PA5-76144

quantity :

100 uL

price :

US 470.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 3

Reference
Li K, Huo Q, Dimmitt N, Qu G, Bao J, Pandya P, et al. Osteosarcoma-enriched transcripts paradoxically generate osteosarcoma-suppressing extracellular proteins. elife. 2023;12: pubmed publisher
Li K, Sun X, Li B, Yokota H. Conversion of Osteoclasts into Bone-Protective, Tumor-Suppressing Cells. Cancers (Basel). 2021;13: pubmed publisher
Liu S, Sun X, Li K, Zha R, Feng Y, Sano T, et al. Generation of the tumor-suppressive secretome from tumor cells. Theranostics. 2021;11:8517-8534 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Ubiquitin C Polyclonal Antibody

Catalog # :

PA5-76144

Quantity :

100 uL

Price :

US 470.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:1,000-1:2,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome.

Immunogen :

Synthetic peptide of human Poly-Ubiquitin.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:1,000-1:2,000

Aliases :

2700054O04Rik; AI194771; HMG20; polyubiquitin C; polyubiquitin-C; Rps27a; TI-225; Uba52; Ubb; Ubc; Ubiquitin; ubiquitin C; Ubiquitin-related; Ubiquitin-related 1; Ubiquitin-related 2