This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
SOX1 Polyclonal Antibody
catalog :
PA5-73017
quantity :
100µg
price :
US 345
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
western clawed frog, human, mouse, rat, dogs
application :
western blot
product information
Product Type :
Antibody
Product Name :
SOX1 Polyclonal Antibody
Catalog # :
PA5-73017
Quantity :
100µg
Price :
US 345
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Canine, Human, Mouse, Non-human primate, Rat, Rodent, Xenopus laevis
Applications :
Western Blot: 1:100-1:1000
Species :
Canine, Human, Mouse, Non-human primate, Rat, Rodent, Xenopus laevis
Isotype :
IgG
Storage :
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Description :
SOX1, also known as SRY (sex determining region Y)-box 1, is a transcription factor belonging to the SRY-related HMG box family of transcription factors with a HMG box DNA-binding domain. SOX1 works through multiple independent pathways to promote neuronal cell fate determination and differentiation. This nuclear protein acts as a modulator of LINE retroposons promoter activity and is also involved in the development of the central nervous system, mainly neural and lens development. Transcriptional activator SOX1 binds directly to the HES1 promoter and suppresses HES1 transcription, thus attenuating Notch signaling. It also binds to beta-catenin and suppresses beta-catenin-mediated TCF/LEF signaling, thus potentially attenuating the WNT signaling pathway. Expression of SOX1 is seen mostly in embryonic tissues and moderately in brain.
Immunogen :
Sox1 antibody against the amino acid sequence 196 RAVHMkEYPDYkYRPRRk 213 was used as the immunogen.
Format :
Liquid
Applications w/Dilutions :
Western Blot: 1:100-1:1000
Aliases :
SRY-related HMG-box gene 1, transcription factor SOX-1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA